Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms SE Jones, JM Lane, AR Wood, VT van Hees, J Tyrrell, RN Beaumont, ... Nature communications 10 (1), 343, 2019 | 521 | 2019 |
Development and standardization of an improved type 1 diabetes genetic risk score for use in newborn screening and incident diagnosis SA Sharp, SS Rich, AR Wood, SE Jones, RN Beaumont, JW Harrison, ... Diabetes care 42 (2), 200-207, 2019 | 243 | 2019 |
Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour SE Jones, VT van Hees, DR Mazzotti, P Marques-Vidal, S Sabia, ... Nature communications 10 (1), 1585, 2019 | 238 | 2019 |
Using genetics to understand the causal influence of higher BMI on depression J Tyrrell, A Mulugeta, AR Wood, A Zhou, RN Beaumont, MA Tuke, ... International journal of epidemiology 48 (3), 834-848, 2019 | 206 | 2019 |
A type 1 diabetes genetic risk score predicts progression of islet autoimmunity and development of type 1 diabetes in individuals at risk MJ Redondo, S Geyer, AK Steck, S Sharp, JM Wentworth, MN Weedon, ... Diabetes care 41 (9), 1887-1894, 2018 | 137 | 2018 |
A combined risk score enhances prediction of type 1 diabetes among susceptible children LA Ferrat, K Vehik, SA Sharp, Å Lernmark, MJ Rewers, JX She, ... Nature medicine 26 (8), 1247-1255, 2020 | 101 | 2020 |
A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure TM Frayling, RN Beaumont, SE Jones, H Yaghootkar, MA Tuke, KS Ruth, ... Cell reports 23 (2), 327-336, 2018 | 92 | 2018 |
Genome-wide association study of microscopic colitis in the UK Biobank confirms immune-related pathogenesis HD Green, RN Beaumont, A Thomas, B Hamilton, AR Wood, S Sharp, ... Journal of Crohn's and Colitis 13 (12), 1578-1582, 2019 | 37 | 2019 |
Clinical and research uses of genetic risk scores in type 1 diabetes SA Sharp, MN Weedon, WA Hagopian, RA Oram Current opinion in genetics & development 50, 96-102, 2018 | 35 | 2018 |
Utility of diabetes type–specific genetic risk scores for the classification of diabetes type among multiethnic youth RA Oram, SA Sharp, C Pihoker, L Ferrat, G Imperatore, A Williams, ... Diabetes care 45 (5), 1124-1131, 2022 | 34 | 2022 |
Type 1 diabetes genetic risk score is discriminative of diabetes in non-Europeans: evidence from a study in India JW Harrison, DSP Tallapragada, A Baptist, SA Sharp, S Bhaskar, KS Jog, ... Scientific Reports 10 (1), 9450, 2020 | 31 | 2020 |
A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care SA Sharp, SE Jones, RA Kimmitt, MN Weedon, AM Halpin, AR Wood, ... Alimentary pharmacology & therapeutics 52 (7), 1165-1173, 2020 | 27 | 2020 |
The Common HNF1A Variant I27L Is a Modifier of Age at Diabetes Diagnosis in Individuals With HNF1A-MODY JM Locke, C Saint-Martin, TW Laver, KA Patel, AR Wood, SA Sharp, ... Diabetes 67 (9), 1903-1907, 2018 | 24 | 2018 |
Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease SE Jones, JM Lane, AR Wood, VT van Hees, J Tyrrell, RN Beaumont, ... BioRxiv, 303941, 2018 | 24 | 2018 |
Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes ALJ Carr, DJ Perry, AL Lynam, S Chamala, CS Flaxman, SA Sharp, ... Diabetic Medicine 37 (12), 2160-2168, 2020 | 20 | 2020 |
IgA nephropathy genetic risk score to estimate the prevalence of IgA nephropathy in UK Biobank K Sukcharoen, SA Sharp, NJ Thomas, RA Kimmitt, J Harrison, C Bingham, ... Kidney International Reports 5 (10), 1643-1650, 2020 | 17 | 2020 |
DR15-DQ6 remains dominantly protective against type 1 diabetes throughout the first five decades of life NJ Thomas, JM Dennis, SA Sharp, A Kaur, S Misra, HC Walkey, ... Diabetologia 64, 2258-2265, 2021 | 15 | 2021 |
Identifying type 1 and 2 diabetes in research datasets where classification biomarkers are unavailable: assessing the accuracy of published approaches NJ Thomas, A McGovern, KG Young, SA Sharp, MN Weedon, ... Journal of clinical epidemiology 153, 34-44, 2023 | 14 | 2023 |
Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour SE Jones, VT Hees, DR Mazzotti, P Marques-Vidal, S Sabia, A der Spek, ... bioRxiv, 303925, 2018 | 13 | 2018 |
Estimating disease prevalence in large datasets using genetic risk scores BD Evans, P Słowiński, AT Hattersley, SE Jones, S Sharp, RA Kimmitt, ... Nature communications 12 (1), 6441, 2021 | 7 | 2021 |