DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect T Ando, T Yoshida, S Enomoto, K Asada, M Tatematsu, M Ichinose, ... International Journal of Cancer 124 (10), 2367-2374, 2009 | 334 | 2009 |
Leptin‐mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats M Kitade, H Yoshiji, H Kojima, Y Ikenaka, R Noguchi, K Kaji, J Yoshii, ... Hepatology 44 (4), 983-991, 2006 | 203 | 2006 |
Methylation-associated silencing of heparan sulfate D-glucosaminyl 3-O-sulfotransferase-2 (3-OST-2) in human breast, colon, lung and pancreatic cancers K Miyamoto, K Asada, T Fukutomi, E Okochi, Y Yagi, T Hasegawa, ... Oncogene 22 (2), 274-280, 2003 | 181 | 2003 |
Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study K Asada, T Nakajima, T Shimazu, N Yamamichi, T Maekita, C Yokoi, I Oda, ... Gut 64 (3), 388-396, 2015 | 147 | 2015 |
Aberrant DNA methylation in contrast with mutations T Ushijima, K Asada Cancer science 101 (2), 300-305, 2010 | 134 | 2010 |
Incidence of and risk factors for metachronous gastric cancer after endoscopic resection and successful Helicobacter pylori eradication: results of a large-scale … G Mori, T Nakajima, K Asada, T Shimazu, N Yamamichi, T Maekita, ... Gastric cancer 19, 911-918, 2016 | 117 | 2016 |
Reduced expression of GNA11 and silencing of MCT1 in human breast cancers K Asada, K Miyamoto, T Fukutomi, H Tsuda, Y Yagi, K Wakazono, S Oishi, ... Oncology 64 (4), 380-388, 2003 | 95 | 2003 |
Amelioration of liver fibrogenesis by dual inhibition of PDGF and TGF-β with a combination of imatinib mesylate and ACE inhibitor in rats H Yoshiji, S Kuriyama, R Noguchi, Y Ikenaka, J Yoshii, K Yanase, ... International journal of molecular medicine 17 (5), 899-904, 2006 | 69 | 2006 |
Promoter hypermethylation and post-transcriptional mechanisms for reduced BRCA1 immunoreactivity in sporadic human breast cancers K Miyamoto, T Fukutomi, K Asada, K Wakazono, H Tsuda, T Asahara, ... Japanese journal of clinical oncology 32 (3), 79-84, 2002 | 65 | 2002 |
High impact of methylation accumulation on metachronous gastric cancer: 5-year follow-up of a multicentre prospective cohort study M Maeda, T Nakajima, I Oda, T Shimazu, N Yamamichi, T Maekita, ... Gut 66 (9), 1721-1723, 2017 | 63 | 2017 |
LINE‐1 hypomethylation in a choline‐deficiency‐induced liver cancer in rats: dependence on feeding period K Asada, Y Kotake, R Asada, D Saunders, RH Broyles, RA Towner, ... BioMed Research International 2006 (1), 017142, 2006 | 60 | 2006 |
FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the formation of an epigenetic field defect K Asada, T Ando, T Niwa, S Nanjo, N Watanabe, E Okochi-Takada, ... Oncogene 32 (17), 2140-2149, 2013 | 56 | 2013 |
Angiotensin-II and vascular endothelial growth factor interaction plays an important role in rat liver fibrosis development H Yoshiji, S Kuriyama, R Noguchi, Y Ikenaka, M Kitade, K Kaji, J Yoshii, ... Hepatology research 36 (2), 124-129, 2006 | 51 | 2006 |
Salvage effect of the vascular endothelial growth factor on chemically induced acute severe liver injury in rats T Namisaki, H Yoshiji, H Kojima, J Yoshii, Y Ikenaka, R Noguchi, ... Journal of hepatology 44 (3), 568-575, 2006 | 49 | 2006 |
Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities H Yoshiji, S Kuriyama, R Noguchi, J Yoshii, Y Ikenaka, K Yanase, ... Oncology Reports 15 (1), 155-159, 2006 | 49 | 2006 |
Ipragliflozin, a sodium–glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long–Evans Tokushima fatty rats N Nishimura, M Kitade, R Noguchi, T Namisaki, K Moriya, K Takeda, ... Journal of gastroenterology 51, 1141-1149, 2016 | 46 | 2016 |
Identification of gastric cancer risk markers that are informative in individuals with past H. pylori infection S Nanjo, K Asada, S Yamashita, T Nakajima, K Nakazawa, T Maekita, ... Gastric Cancer 15, 382-388, 2012 | 46 | 2012 |
Crosstalk between high-molecular-weight adiponectin and T-cadherin during liver fibrosis development in rats K Asada, H Yoshiji, R Noguchi, Y Ikenaka, M Kitade, K Kaji, J Yoshii, ... International journal of molecular medicine 20 (5), 725-729, 2007 | 46 | 2007 |
Hereditary diffuse gastric cancer in a Japanese family with a large deletion involving CDH1 M Yamada, T Fukagawa, T Nakajima, K Asada, S Sekine, S Yamashita, ... Gastric Cancer 17, 750-756, 2014 | 44 | 2014 |
Association between frequent CpG island methylation and HER2 amplification in human breast cancers K Terada, E Okochi-Takada, S Akashi-Tanaka, K Miyamoto, K Taniyama, ... Carcinogenesis 30 (3), 466-471, 2009 | 41 | 2009 |