Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, ... Nature Communications 7, 13128, 2016 | 177 | 2016 |
α, β-Unsaturated diazoketones as useful platforms in the synthesis of nitrogen heterocycles ACB Burtoloso, RMP Dias, B Bernardim Accounts of Chemical Research 48 (4), 921-934, 2015 | 77 | 2015 |
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, ... Angewandte Chemie International Edition 58 (20), 6640-6644, 2019 | 76 | 2019 |
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ... Nature Protocols 14 (1), 86-99, 2019 | 71 | 2019 |
LED lighting as a simple, inexpensive, and sustainable alternative for Wolff rearrangements B Bernardim, AM Hardman-Baldwin, ACB Burtoloso RSC Advances 5 (18), 13311-13314, 2015 | 56 | 2015 |
α, β-unsaturated diazoketones as platforms in the asymmetric synthesis of hydroxylated alkaloids. Total synthesis of 1-deoxy-8, 8a-diepicastanospermine and 1, 6 … B Bernardim, VD Pinho, ACB Burtoloso The Journal of Organic Chemistry 77 (21), 9926-9931, 2012 | 38 | 2012 |
Advances in the enantioselective metal-catalyzed NH and OH insertion reactions with diazocarbonyl compounds A CB Burtoloso, J V Santiago, B Bernardim, A G Talero Current Organic Synthesis 12 (5), 650-659, 2015 | 32 | 2015 |
Divergent roles of urea and phosphoric acid derived catalysts in reactions of diazo compounds B Bernardim, ED Couch, AM Hardman-Baldwin, ACB Burtoloso, ... Synthesis 48 (05), 677-686, 2016 | 26 | 2016 |
A Microfluidic Co‐Flow Route for Human Serum Albumin‐Drug–Nanoparticle Assembly TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, ... Chemistry–A European Journal 26 (27), 5965-5969, 2020 | 25 | 2020 |
Enhancement of the anti-aggregation activity of a molecular chaperone using a rationally designed post-translational modification PR Lindstedt, FA Aprile, MJ Matos, M Perni, JB Bertoldo, B Bernardim, ... ACS Central Science 5 (8), 1417-1424, 2019 | 18 | 2019 |
Precise installation of diazo-tagged side-chains on proteins to enable in vitro and in-cell site-specific labeling B Bernardim, L Dunsmore, H Li, B Hocking, R Nuñez-Franco, CD Navo, ... Bioconjugate Chemistry 31 (6), 1604-1610, 2020 | 17 | 2020 |
Sharpless asymmetric dihydroxylation on α, β-unsaturated diazoketones: a new entry for the synthesis of disubstituted furanones AG Talero, ACB Burtoloso Synlett 28 (14), 1748-1752, 2017 | 15 | 2017 |
A two-step synthesis of the bioprotective agent JP4-039 from N-Boc-L-leucinal B Bernardim, ACB Burtoloso Tetrahedron 70 (20), 3291-3296, 2014 | 10 | 2014 |
Saéz, IS Albuquerque, E B Bernardim, P Cal, MJ Matos, BL Oliveira, N Martínez Perkins, F. Corzana, B. Burtoloso, G. Jiménez-‐Osés and G. Bernardes, Nat …, 2016 | 9 | 2016 |
α, β-unsaturated diazoketones as versatile building blocks for the synthesis of hydroxylated piperidines, indolizidines and quinolizidines B Bernardim, L D. Lordello, A CB Burtoloso Current Topics in Medicinal Chemistry 13 (17), 2099-2103, 2013 | 9 | 2013 |
Sequential dual site-selective protein labelling enabled by lysine modification MJ Matos, L Brown, B Bernardim, A Guerreiro, G Jimenez-Oses, ... Bioorganic & Medicinal Chemistry 28 (22), 115783, 2020 | 5 | 2020 |
Synthesis of 5-substituted 2-pyrrolidinones by coupling of organozinc reagents with cyclic N-acyliminium ions I Zaragoza-Galicia, ZA Santos-Sánchez, YI Hidalgo-Mercado, HF Olivo, ... Synthesis 51 (24), 4650-4656, 2019 | 2 | 2019 |
Cathepsin B Processing Is Required for the In Vivo Efficacy of Albumin–Drug Conjugates B Bernardim, J Conde, T Hakala, JB Becher, M Canzano, AV Vasco, ... Bioconjugate Chemistry 35 (2), 132-139, 2024 | 1 | 2024 |
Synthesis of Aryl-Substituted 3, 3a, 4, 5-Tetrahydropyrrolo [1, 2-a] quinolin-1 (2H)-ones and 2, 3, 4, 4a, 5, 6-Hexahydro-1H-pyrido [1, 2-a] quinolin-1-ones FM Watts, RA Bunce Synthesis 51 (02), 564-572, 2019 | | 2019 |
Alfa, Beta-Unsaturated diazoketones as substrates for intramolecular [2+ 2] and [4+ 2] cycloadditions B Bernardim, ACB Burtoloso Proceedings, 2017 | | 2017 |