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David N Hauser
David N Hauser
Neurocrine Biosciences
在 neurocrine.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Dopamine: functions, signaling, and association with neurological diseases
MO Klein, DS Battagello, AR Cardoso, DN Hauser, JC Bittencourt, ...
Cellular and molecular neurobiology 39 (1), 31-59, 2019
8612019
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
D Narendra, LA Kane, DN Hauser, IM Fearnley, RJ Youle
Autophagy 6 (8), 1090-1106, 2010
8482010
Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism
DN Hauser, TG Hastings
Neurobiology of disease 51, 35-42, 2013
5202013
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
A Beilina, IN Rudenko, A Kaganovich, L Civiero, H Chau, SK Kalia, ...
Proceedings of the National Academy of Sciences 111 (7), 2626-2631, 2014
3782014
mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex
AA Dillman, DN Hauser, JR Gibbs, MA Nalls, MK McCoy, IN Rudenko, ...
Nature neuroscience 16 (4), 499-506, 2013
1502013
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation
IN Rudenko, A Kaganovich, DN Hauser, A Beylina, R Chia, J Ding, ...
Biochemical Journal 446 (1), 99-111, 2012
1312012
The road ahead for health and lifespan interventions
M Gonzalez-Freire, A Diaz-Ruiz, D Hauser, J Martinez-Romero, L Ferrucci, ...
Ageing research reviews 59, 101037, 2020
942020
Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4
DN Hauser, AA Dukes, AD Mortimer, TG Hastings
Free Radical Biology and Medicine 65, 419-427, 2013
902013
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice
L Pellegrini, DN Hauser, Y Li, A Mamais, A Beilina, R Kumaran, A Wetzel, ...
Human molecular genetics 27 (18), 3257-3271, 2018
622018
Hexokinases link DJ-1 to the PINK1/parkin pathway
DN Hauser, A Mamais, MM Conti, CT Primiani, R Kumaran, AA Dillman, ...
Molecular neurodegeneration 12, 1-17, 2017
532017
Arsenite stress down-regulates phosphorylation and 14-3-3 binding of leucine-rich repeat kinase 2 (LRRK2), promoting self-association and cellular redistribution
A Mamais, R Chia, A Beilina, DN Hauser, C Hall, PA Lewis, MR Cookson, ...
Journal of Biological Chemistry 289 (31), 21386-21400, 2014
512014
The Effects of Variants in the Parkin, PINK1, and DJ-1 Genes along with Evidence for their Pathogenicity
D N Hauser, C T Primiani, M R Cookson
Current Protein and Peptide Science 18 (7), 702-714, 2017
242017
The Polg mutator phenotype does not cause dopaminergic neurodegeneration in DJ-1-deficient mice
DN Hauser, CT Primiani, RG Langston, R Kumaran, MR Cookson
Eneuro 2 (1), 2015
222015
Astrocytes in Parkinson’s disease and DJ-1
D Hauser, MR Cookson
Journal of neurochemistry 117 (3), 357, 2011
222011
Use of cysteine‐reactive cross‐linkers to probe conformational flexibility of human DJ‐1 demonstrates that Glu18 mutations are dimers
J Prahlad, DN Hauser, NM Milkovic, MR Cookson, MA Wilson
Journal of neurochemistry 130 (6), 839-853, 2014
202014
Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain
DN Hauser, AA Dillman, J Ding, Y Li, MR Cookson
PLoS One 9 (4), e94646, 2014
172014
Differences in stability, activity and mutation effects between human and mouse leucine-rich repeat kinase 2
RG Langston, IN Rudenko, R Kumaran, DN Hauser, A Kaganovich, ...
Neurochemical research 44, 1446-1459, 2019
112019
Longitudinal characterization of transcriptomic, functional, and morphological features in human iPSC-derived neurons and their application to investigate translational …
G Robin, JC Evans, DN Hauser, P Wren, A Zembrzycki
Frontiers in Aging Neuroscience 12, 576678, 2020
52020
Generation of iPSC line from a Parkinson patient with PARK7 mutation and CRISPR-edited Gibco human episomal iPSC line to mimic PARK7 mutation
MC Mazza, A Beilina, DA Roosen, D Hauser, MR Cookson
Stem cell research 55, 102506, 2021
42021
Dopamine Oxidation and Quinone Modification of Proteins: Mechanisms of Toxicity and Implications for Parkinson’s Disease
TG Hastings, A Mortimer, D Hauser
Catecholamine Research in the 21st Century, 122, 2014
2014
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