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Kevin James Metcalf
Kevin James Metcalf
在 ucsf.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Concepts of extracellular matrix remodelling in tumour progression and metastasis
J Winkler, A Abisoye-Ogunniyan, KJ Metcalf, Z Werb
Nature communications 11 (1), 5120, 2020
13942020
Type III secretion as a generalizable strategy for the production of full‐length biopolymer‐forming proteins
A Azam, C Li, KJ Metcalf, D Tullman‐Ercek
Biotechnology and bioengineering 113 (11), 2313-2320, 2016
472016
Directed evolution of brain-derived neurotrophic factor for improved folding and expression in Saccharomyces cerevisiae
ML Burns, TM Malott, KJ Metcalf, BJ Hackel, JR Chan, EV Shusta
Applied and environmental microbiology 80 (18), 5732-5742, 2014
362014
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
K Pedram, DJ Shon, GS Tender, NR Mantuano, JJ Northey, KJ Metcalf, ...
Nature biotechnology 42 (4), 597-607, 2024
302024
Leveraging microenvironmental synthetic lethalities to treat cancer
KJ Metcalf, A Alazzeh, Z Werb, VM Weaver
The Journal of Clinical Investigation 131 (6), 2021
252021
Using transcriptional control to increase titers of secreted heterologous proteins by the type III secretion system
KJ Metcalf, C Finnerty, A Azam, E Valdivia, D Tullman-Ercek
Applied and Environmental Microbiology 80 (19), 5927-5934, 2014
222014
Long-Range Energy Transfer in Protein Megamolecules
EL Taylor, KJ Metcalf, B Carlotti, CT Lai, JA Modica, GC Schatz, M Mrksich, ...
Journal of the American Chemical Society 140 (46), 15731-15743, 2018
162018
Proteins adopt functionally active conformations after type III secretion
KJ Metcalf, JL Bevington, SL Rosales, LA Burdette, E Valdivia, ...
Microbial Cell Factories 15, 1-10, 2016
162016
Photoactivatable reaction for covalent nanoscale patterning of multiple proteins
S Zhou, KJ Metcalf, P Bugga, J Grant, M Mrksich
ACS applied materials & interfaces 10 (47), 40452-40459, 2018
122018
Synthetic Tuning of Domain Stoichiometry in Nanobody–Enzyme Megamolecules
KJ Metcalf, BR Kimmel, DJ Sykora, JA Modica, KA Parker, E Berens, ...
Bioconjugate chemistry 32 (1), 143-152, 2020
82020
A machine learning strategy for the identification of key in silico descriptors and prediction models for IgG monoclonal antibody developability properties
AB Waight, D Prihoda, R Shrestha, K Metcalf, M Bailly, M Ancona, ...
MAbs 15 (1), 2248671, 2023
72023
Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression
KJ Metcalf, MK Hayward, E Berens, AJ Ironside, C Stashko, ES Hwang, ...
Matrix Biology Plus 14, 100105, 2022
62022
Role of lipopolysaccharide in protecting OmpT from autoproteolysis during in vitro refolding
G Sinsinbar, S Gudlur, KJ Metcalf, M Mrksich, M Nallani, B Liedberg
Biomolecules 10 (6), 922, 2020
62020
Pro‐region engineering for improved yeast display and secretion of brain derived neurotrophic factor
ML Burns, TM Malott, KJ Metcalf, A Puguh, JR Chan, EV Shusta
Biotechnology Journal 11 (3), 425-436, 2016
62016
An estimate is worth about a thousand experiments: using order-of-magnitude estimates to identify cellular engineering targets
KJ Metcalf, MF Slininger Lee, CM Jakobson, D Tullman-Ercek
Microbial Cell Factories 17, 1-10, 2018
12018
Use of transcriptional control to increase secretion of heterologous proteins in T3S systems
KJ Metcalf, D Tullman-Ercek
Type 3 Secretion Systems: Methods and Protocols, 71-79, 2017
12017
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