Concepts of extracellular matrix remodelling in tumour progression and metastasis J Winkler, A Abisoye-Ogunniyan, KJ Metcalf, Z Werb Nature communications 11 (1), 5120, 2020 | 1394 | 2020 |
Type III secretion as a generalizable strategy for the production of full‐length biopolymer‐forming proteins A Azam, C Li, KJ Metcalf, D Tullman‐Ercek Biotechnology and bioengineering 113 (11), 2313-2320, 2016 | 47 | 2016 |
Directed evolution of brain-derived neurotrophic factor for improved folding and expression in Saccharomyces cerevisiae ML Burns, TM Malott, KJ Metcalf, BJ Hackel, JR Chan, EV Shusta Applied and environmental microbiology 80 (18), 5732-5742, 2014 | 36 | 2014 |
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins K Pedram, DJ Shon, GS Tender, NR Mantuano, JJ Northey, KJ Metcalf, ... Nature biotechnology 42 (4), 597-607, 2024 | 30 | 2024 |
Leveraging microenvironmental synthetic lethalities to treat cancer KJ Metcalf, A Alazzeh, Z Werb, VM Weaver The Journal of Clinical Investigation 131 (6), 2021 | 25 | 2021 |
Using transcriptional control to increase titers of secreted heterologous proteins by the type III secretion system KJ Metcalf, C Finnerty, A Azam, E Valdivia, D Tullman-Ercek Applied and Environmental Microbiology 80 (19), 5927-5934, 2014 | 22 | 2014 |
Long-Range Energy Transfer in Protein Megamolecules EL Taylor, KJ Metcalf, B Carlotti, CT Lai, JA Modica, GC Schatz, M Mrksich, ... Journal of the American Chemical Society 140 (46), 15731-15743, 2018 | 16 | 2018 |
Proteins adopt functionally active conformations after type III secretion KJ Metcalf, JL Bevington, SL Rosales, LA Burdette, E Valdivia, ... Microbial Cell Factories 15, 1-10, 2016 | 16 | 2016 |
Photoactivatable reaction for covalent nanoscale patterning of multiple proteins S Zhou, KJ Metcalf, P Bugga, J Grant, M Mrksich ACS applied materials & interfaces 10 (47), 40452-40459, 2018 | 12 | 2018 |
Synthetic Tuning of Domain Stoichiometry in Nanobody–Enzyme Megamolecules KJ Metcalf, BR Kimmel, DJ Sykora, JA Modica, KA Parker, E Berens, ... Bioconjugate chemistry 32 (1), 143-152, 2020 | 8 | 2020 |
A machine learning strategy for the identification of key in silico descriptors and prediction models for IgG monoclonal antibody developability properties AB Waight, D Prihoda, R Shrestha, K Metcalf, M Bailly, M Ancona, ... MAbs 15 (1), 2248671, 2023 | 7 | 2023 |
Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression KJ Metcalf, MK Hayward, E Berens, AJ Ironside, C Stashko, ES Hwang, ... Matrix Biology Plus 14, 100105, 2022 | 6 | 2022 |
Role of lipopolysaccharide in protecting OmpT from autoproteolysis during in vitro refolding G Sinsinbar, S Gudlur, KJ Metcalf, M Mrksich, M Nallani, B Liedberg Biomolecules 10 (6), 922, 2020 | 6 | 2020 |
Pro‐region engineering for improved yeast display and secretion of brain derived neurotrophic factor ML Burns, TM Malott, KJ Metcalf, A Puguh, JR Chan, EV Shusta Biotechnology Journal 11 (3), 425-436, 2016 | 6 | 2016 |
An estimate is worth about a thousand experiments: using order-of-magnitude estimates to identify cellular engineering targets KJ Metcalf, MF Slininger Lee, CM Jakobson, D Tullman-Ercek Microbial Cell Factories 17, 1-10, 2018 | 1 | 2018 |
Use of transcriptional control to increase secretion of heterologous proteins in T3S systems KJ Metcalf, D Tullman-Ercek Type 3 Secretion Systems: Methods and Protocols, 71-79, 2017 | 1 | 2017 |