| Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates DM Stresser, AP Blanchard, SD Turner, JCL Erve, AA Dandeneau, ... Drug Metabolism and Disposition 28 (12), 1440-1448, 2000 | 346 | 2000 |
| Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity GL Henderson, MR Harkey, ME Gershwin, RM Hackman, JS Stern, ... Life sciences 65 (15), PL209-PL214, 1999 | 204 | 1999 |
| In vitro and pharmacophore insights into CYP3A enzymes S Ekins, DM Stresser, JA Williams Trends in pharmacological sciences 24 (4), 161-166, 2003 | 197 | 2003 |
| Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4. DM Stresser, SD Turner, AP Blanchard, VP Miller, CL Crespi Drug Metabolism and Disposition 30 (7), 845-852, 2002 | 197 | 2002 |
| In vitro drug metabolism using liver microsomes KM Knights, DM Stresser, JO Miners, CL Crespi Current protocols in pharmacology 74 (1), 7.8. 1-7.8. 24, 2016 | 191 | 2016 |
| Fluorometric screening for metabolism-based drug–drug interactions CL Crespi, DM Stresser Journal of pharmacological and toxicological methods 44 (1), 325-331, 2000 | 165 | 2000 |
| A high-throughput screen to identify inhibitors of aromatase (CYP19) DM Stresser, SD Turner, J McNamara, P Stocker, VP Miller, CL Crespi, ... Analytical biochemistry 284 (2), 427-430, 2000 | 161 | 2000 |
| Monospecific antipeptide antibody to cytochrome P-450 2B6 DM Stresser, D Kupfer Drug Metabolism and Disposition 27 (4), 517-525, 1999 | 159 | 1999 |
| Highly selective inhibition of human CYP3A in vitro by azamulin and evidence that inhibition is irreversible DM Stresser, MI Broudy, T Ho, CE Cargill, AP Blanchard, R Sharma, ... Drug Metabolism and Disposition 32 (1), 105-112, 2004 | 156 | 2004 |
| Indole-3-carbinol and beta-naphthoflavone induction of aflatoxin B1 metabolism and cytochromes P-450 associated with bioactivation and detoxication of aflatoxin B1 in the rat. DM Stresser, GS Bailey, DE Williams Drug metabolism and disposition 22 (3), 383-391, 1994 | 132 | 1994 |
| Mechanisms of tumor modulation by indole-3-carbinol. Disposition and excretion in male Fischer 344 rats. DM Stresser, DE Williams, DA Griffin, GS Bailey Drug metabolism and disposition 23 (9), 965-975, 1995 | 130 | 1995 |
| Fluorometric high‐throughput screening for inhibitors of cytochrome P450 VP Miller, DM Stresser, AP Blanchard, S Turner, CL Crespi Annals of the New York Academy of Sciences 919 (1), 26-32, 2000 | 125 | 2000 |
| Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG cells DF McGinnity, G Zhang, JR Kenny, GA Hamilton, S Otmani, KR Stams, ... Drug metabolism and disposition 37 (6), 1259-1268, 2009 | 121 | 2009 |
| Human cytochrome P450–catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen: Role of CYP2C19 and CYP1A2 inO-demethylation DM Stresser, D Kupfer Drug Metabolism and disposition 26 (9), 868-874, 1998 | 114 | 1998 |
| Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design ES Perloff, AK Mason, SS Dehal, AP Blanchard, L Morgan, T Ho, ... Xenobiotica 39 (2), 99-112, 2009 | 102 | 2009 |
| Indole-3-carbinol induces a rat liver glutathione transferase subunit (Yc2) with high activity toward aflatoxin B1 exo-epoxide. Association with reduced levels of hepatic … DM Stresser, DE Williams, LI McLellan, TM Harris, GS Bailey Drug metabolism and disposition 22 (3), 392-399, 1994 | 86 | 1994 |
| Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit. SE Shehin-Johnson, DE Williams, S Larsen-Su, DM Stresser, RN Hines Journal of Pharmacology and Experimental Therapeutics 272 (3), 1293-1299, 1995 | 85 | 1995 |
| The anticarcinogen 3, 3′‐diindolylmethane is an inhibitor of cytochrome P‐450 DM Stresser, GS Bailey, DE Williams, LF Bjeldanes Journal of biochemical toxicology 10 (4), 191-201, 1995 | 74 | 1995 |
| Concurrent flavin-containing monooxygenase down-regulation and cytochrome P-450 induction by dietary indoles in rat: implications for drug-drug interaction S Katchamart, DM Stresser, SS Dehal, D Kupfer, DE Williams Drug Metabolism and Disposition 28 (8), 930-936, 2000 | 70 | 2000 |
| The use of 3-[2-(N, N-diethyl-N-methylammonium) ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes N Chauret, B Dobbs, RL Lackman, K Bateman, DA Nicoll-Griffith, ... Drug metabolism and disposition 29 (9), 1196-1200, 2001 | 65 | 2001 |
