High serum concentrations of the acyclovir main metabolite 9‐carboxymethoxymethylguanine in renal failure patients with acyclovir‐related neuropsychiatric side effects: an … A Helldén, I Odar‐Cederlöf, P Diener, L Barkholt, C Medin, JO Svensson, ... Nephrology Dialysis Transplantation 18 (6), 1135-1141, 2003 | 127 | 2003 |
Adverse drug reactions and impaired renal function in elderly patients admitted to the emergency department: a retrospective study A Helldén, U Bergman, M von Euler, M Hentschke, I Odar-Cederlöf, ... Drugs & aging 26, 595-606, 2009 | 124 | 2009 |
The aciclovir metabolite CMMG is detectable in the CSF of subjects with neuropsychiatric symptoms during aciclovir and valaciclovir treatment A Helldén, J Lycke, T Vander, JO Svensson, I Odar-Cederlöf, L Ståhle Journal of Antimicrobial Chemotherapy 57 (5), 945-949, 2006 | 80 | 2006 |
Renal function estimations and dose recommendations for dabigatran, gabapentin and valaciclovir: a data simulation study focused on the elderly A Helldén, I Odar-Cederlöf, G Nilsson, S Sjöviker, A Söderström, ... BMJ open 3 (4), e002686, 2013 | 73 | 2013 |
Pulmonary embolism associated with the use of anabolic steroids S Liljeqvist, A Helldén, U Bergman, M Söderberg European Journal of Internal Medicine 19 (3), 214-215, 2008 | 47 | 2008 |
Lakemedelsbiverkan som orsak till inlaggning pa sjukhus: Vanliga medel star for merparten, visar tvarsnittsstudie I Odar-Cederlof, P Oskarsson, G Ohlen, Y Tesfa, A Bergendal, A Hellden, ... Lakartidningen 105 (12/13), 890, 2008 | 32 | 2008 |
Death delusion A Helldén, I Odar-Cederlöf, K Larsson, I Fehrman-Ekholm, T Lindén Bmj 335 (7633), 1305-1305, 2007 | 31 | 2007 |
Aciclovir induced posterior leucoencephalopathy D Mahad, J Jarvis, PF Chinnery, D Mitra, A Gholkar, A Helldén Journal of Neurology, Neurosurgery & Psychiatry 76 (9), 1308-1309, 2005 | 22 | 2005 |
Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9 A Helldén, U Bergman, K Engström Hellgren, M Masquelier, ... European journal of clinical pharmacology 66, 791-795, 2010 | 21 | 2010 |
Lower CYP2C9 activity in Turkish patients with Behçet’s disease compared to healthy subjects: a down-regulation due to inflammation? MT Goktaş, F Hatta, O Karaca, S Kalkisim, L Kilic, A Akdogan, ... European journal of clinical pharmacology 71, 1223-1228, 2015 | 19 | 2015 |
Development of a computerised decisions support system for renal risk drugs targeting primary healthcare A Helldén, F Al-Aieshy, P Bastholm-Rahmner, U Bergman, LL Gustafsson, ... BMJ open 5 (7), e006775, 2015 | 18 | 2015 |
Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A> T and the losartan metabolism phenotype in Swedes FHM Hatta, LK Teh, A Helldén, KE Hellgren, HK Roh, MZ Salleh, E Aklillu, ... European journal of clinical pharmacology 68, 1033-1042, 2012 | 17 | 2012 |
Rapid determination of acyclovir, its main metabolite 9‐carboxymethoxymethylguanine, ganciclovir, and penciclovir in human serum using LC–MS/MS A Ärlemalm, A Helldén, L Karlsson, B Carlsson Biomedical Chromatography 36 (4), e5315, 2022 | 13 | 2022 |
An unexpectedly high occurrence of aciclovir-induced neuropsychiatric symptoms in patients treated for herpesvirus CNS infection: a prospective observational study J Lindström, A Helldén, J Lycke, A Grahn, M Studahl Journal of Antimicrobial Chemotherapy 74 (12), 3565-3572, 2019 | 13 | 2019 |
Case report: subtherapeutic vancomycin and meropenem concentrations due to augmented renal clearance in a patient with intracranial infection caused by Streptococcus intermedius M Fransson, A Helldén, Å Östholm Balkhed, D Nezirević Dernroth, M Ha, ... Frontiers in Pharmacology 12, 728075, 2021 | 12 | 2021 |
Pregnancy and pharmacogenomics in the context of drug metabolism and response A Helldén, P Madadi Pharmacogenomics 14 (14), 1779-1791, 2013 | 12 | 2013 |
The dopaminergic stabilizer pridopidine is to a major extent N-depropylated by CYP2D6 in humans A Helldén, G Panagiotidis, P Johansson, N Waters, S Waters, J Tedroff, ... European journal of clinical pharmacology 68, 1281-1286, 2012 | 12 | 2012 |
Ganciclovir concentrations in the cerebral extracellular space after valganciclovir treatment; a case study I Peredo, A Helldén, N Wolmer-Solberg, A Pohanka, G Stragliotto, ... Case Reports 2015, bcr2014207694, 2015 | 10 | 2015 |
Differential diagnosis of central nervous system involvement in a patient treated with acyclovir M von Euler, G Axelsson, A Helldén Therapeutic drug monitoring 35 (4), 417-419, 2013 | 10 | 2013 |
The importance of correct estimation of renal function for drug treatment in hospitalized elderly patients, especially women: a prospective observational study A Helldén, U Bergman, I Odar-Cederlöf Clinical Nephrology 91 (4), 254, 2019 | 7 | 2019 |