The pathogenesis of lupus nephritis M Lech, HJ Anders Journal of the American Society of Nephrology 24 (9), 1357-1366, 2013 | 522 | 2013 |
Macrophages and fibrosis: How resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair M Lech, HJ Anders Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (7), 989-997, 2013 | 490 | 2013 |
Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation KM Jeltsch, D Hu, S Brenner, J Zöller, GA Heinz, D Nagel, KU Vogel, ... Nature immunology 15 (11), 1079-1089, 2014 | 296 | 2014 |
Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus RD Pawar, A Ramanjaneyulu, OP Kulkarni, M Lech, S Segerer, ... Journal of the American Society of Nephrology 18 (6), 1721-1731, 2007 | 258 | 2007 |
Macrophage phenotype controls long-term AKI outcomes—kidney regeneration versus atrophy M Lech, R Gröbmayr, M Ryu, G Lorenz, I Hartter, SR Mulay, HE Susanti, ... Journal of the American Society of Nephrology 25 (2), 292-304, 2014 | 226 | 2014 |
Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death K Neumann, M Castineiras-Vilarino, U Höckendorf, N Hannesschläger, ... Immunity 40 (3), 389-399, 2014 | 197 | 2014 |
Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice M Lech, A Avila-Ferrufino, V Skuginna, HE Susanti, HJ Anders International immunology 22 (9), 717-728, 2010 | 182 | 2010 |
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas (lpr) mice PS Patole, RD Pawar, M Lech, D Zecher, H Schmidt, S Segerer, A Ellwart, ... Nephrology Dialysis Transplantation 21 (11), 3062-3073, 2006 | 163 | 2006 |
Tob38, a novel essential component in the biogenesis of β‐barrel proteins of mitochondria T Waizenegger, SJ Habib, M Lech, D Mokranjac, SA Paschen, K Hell, ... EMBO reports 5 (7), 704-709, 2004 | 150 | 2004 |
Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens M Lech, OP Kulkarni, S Pfeiffer, E Savarese, A Krug, C Garlanda, ... The Journal of experimental medicine 205 (8), 1879-1888, 2008 | 135 | 2008 |
Ligands to nucleic acid–specific toll-like receptors and the onset of lupus nephritis RD Pawar, PS Patole, A Ellwart, M Lech, S Segerer, D Schlondorff, ... Journal of the American Society of Nephrology 17 (12), 3365-3373, 2006 | 128 | 2006 |
Loss of Roquin induces early death and immune deregulation but not autoimmunity A Bertossi, M Aichinger, P Sansonetti, M Lech, F Neff, M Pal, ... Journal of Experimental Medicine 208 (9), 1749-1756, 2011 | 116 | 2011 |
Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein M Lech, A Avila-Ferrufino, R Allam, S Segerer, A Khandoga, F Krombach, ... The Journal of Immunology 183 (6), 4109-4118, 2009 | 110 | 2009 |
Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury M Lech, C Römmele, R Gröbmayr, HE Susanti, OP Kulkarni, S Wang, ... Kidney international 83 (4), 647-661, 2013 | 100 | 2013 |
Tissues use resident dendritic cells and macrophages to maintain homeostasis and to regain homeostasis upon tissue injury: the immunoregulatory role of changing tissue environments M Lech, R Gröbmayr, M Weidenbusch, HJ Anders Mediators of inflammation 2012 (1), 951390, 2012 | 96 | 2012 |
Only hyperuricemia with crystalluria, but not asymptomatic hyperuricemia, drives progression of chronic kidney disease M Sellmayr, MRH Petzsche, Q Ma, N Krüger, H Liapis, A Brink, B Lenz, ... Journal of the American Society of Nephrology 31 (12), 2773-2792, 2020 | 95 | 2020 |
Assembly of the TOB complex of mitochondria SJ Habib, T Waizenegger, M Lech, W Neupert, D Rapaport Journal of Biological Chemistry 280 (8), 6434-6440, 2005 | 95 | 2005 |
Hyperoxaluria requires TNF receptors to initiate crystal adhesion and kidney stone disease SR Mulay, JN Eberhard, J Desai, JA Marschner, SVR Kumar, ... Journal of the American Society of Nephrology 28 (3), 761-768, 2017 | 94 | 2017 |
Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells M Lech, C Garlanda, A Mantovani, CJ Kirschning, D Schlöndorff, ... Kidney international 72 (2), 182-192, 2007 | 92 | 2007 |
NLRP3 and ASC suppress lupus-like autoimmunity by driving the immunosuppressive effects of TGF-β receptor signalling M Lech, G Lorenz, OP Kulkarni, MOO Grosser, N Stigrot, MN Darisipudi, ... Annals of the rheumatic diseases 74 (12), 2224-2235, 2015 | 91 | 2015 |