SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness KS Corbett, DK Edwards, SR Leist, OM Abiona, S Boyoglu-Barnum, ... Nature 586 (7830), 567-571, 2020 | 1486 | 2020 |
Higher-Order Organization Principles of Pre-translational mRNPs M Metkar, H Ozadam, BR Lajoie, M Imakaev, LA Mirny, J Dekker, ... Molecular Cell 72 (4), P715-726.E3, 2018 | 63 | 2018 |
Coronavirus rna vaccines M Metkar, V Presnyak, G Stewart-Jones US Patent App. 17/000,215, 2021 | 35 | 2021 |
Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved alternative splicing nonsense-mediated decay pathways C Kovalak, S Donovan, AA Bicknell, M Metkar, MJ Moore Genome biology 22, 1-21, 2021 | 17 | 2021 |
Tailor made: the art of therapeutic mRNA design M Metkar, CS Pepin, MJ Moore Nature Reviews Drug Discovery 23 (1), 67-83, 2024 | 13 | 2024 |
Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay AA Bicknell, DW Reid, MC Licata, AK Jones, YM Cheng, M Li, CJ Hsiao, ... Cell Reports 43 (4), 2024 | 2 | 2024 |
Coronavirus rna vaccines G Stewart-Jones, E Narayanan, H Bennett, A Carfi, M Metkar, V Presnyak US Patent App. 17/796,208, 2023 | 2 | 2023 |
Coronavirus rna vaccines M Metkar, V Presnyak US Patent App. 17/518,542, 2022 | 1 | 2022 |
RIPPLiT and ChimeraTie: High throughput tools for understanding higher order RNP structures M Metkar | 1 | 2018 |
mRNA secondary structure prediction using utility-scale quantum computers D Alevras, M Metkar, T Yamamoto, V Kumar, T Friedhoff, JE Park, ... arXiv preprint arXiv:2405.20328, 2024 | | 2024 |
Multi-proline-substituted coronavirus spike protein vaccines G Stewart-Jones, M Metkar, V Presnyak US Patent App. 18/028,126, 2023 | | 2023 |
Sars-cov-2 mrna domain vaccines G Stewart-Jones, A Carfi, SM Elbashir, M Metkar US Patent App. 17/797,784, 2023 | | 2023 |
Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved AS-NMD pathways [preprint] C Kovalak, M Metkar, MJ Moore | | 2019 |
Higher-Order Organization Principles of Pre-translational mRNPs [preprint] M Metkar, H Ozadam, BR Lajoie, M Imakaev, LA Mirny, J Dekker, ... | | 2018 |