Mechanisms and consequences of endothelial cell senescence SI Bloom, MT Islam, LA Lesniewski, AJ Donato Nature Reviews Cardiology 20 (1), 38-51, 2023 | 148 | 2023 |
Advanced age results in a diminished endothelial glycocalyx DR Machin, SI Bloom, RA Campbell, TTT Phuong, PE Gates, ... American Journal of Physiology-Heart and Circulatory Physiology 315 (3 …, 2018 | 101 | 2018 |
A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes LH Yuen, S Dana, Y Liu, SI Bloom, AG Thorsell, D Neri, AJ Donato, ... Journal of the American Chemical Society 141 (13), 5169-5181, 2019 | 95 | 2019 |
The role of senescence, telomere dysfunction and shelterin in vascular aging Y Liu, SI Bloom, AJ Donato Microcirculation 26 (2), e12487, 2019 | 68 | 2019 |
Effects of a combined protein and antioxidant supplement on recovery of muscle function and soreness following eccentric exercise SJ Ives, S Bloom, A Matias, N Morrow, N Martins, Y Roh, D Ebenstein, ... Journal of the International Society of Sports Nutrition 14, 1-10, 2017 | 50 | 2017 |
Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress RG Morgan, AE Walker, DW Trott, DR Machin, GD Henson, KD Reihl, ... Journal of molecular and cellular cardiology 127, 74-82, 2019 | 30 | 2019 |
Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments SI Bloom, Y Liu, JR Tucker, MT Islam, DR Machin, H Abdeahad, ... Aging Cell 22 (8), e13875, 2023 | 18 | 2023 |
Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions SI Bloom, JR Tucker, J Lim, TG Thomas, GJ Stoddard, LA Lesniewski, ... Geroscience 44 (6), 2741-2755, 2022 | 18 | 2022 |
Firefighting induces acute inflammatory responses that are not relieved by aspirin in older firefighters DL Smith, NMG Friedman, SI Bloom, WL Armero, BD Pence, MD Cook, ... Journal of occupational and environmental medicine 61 (7), 617-622, 2019 | 17 | 2019 |
Implications of endothelial shear stress on systemic sclerosis vasculopathy and treatment TM Frech, DR Machin, MA Murtaugh, GJ Stoddard, SI Bloom, JV Phibbs, ... Clinical and experimental rheumatology 36 (Suppl 113), 175, 2018 | 17 | 2018 |
High‐fat diet induced obesity and age influence the telomere shelterin complex and telomerase gene expression in mouse adipose tissue SI Bloom, A Tuluca, SJ Ives, TH Reynolds Physiological reports 8 (11), e14461, 2020 | 15 | 2020 |
T cells mediate cell non‐autonomous arterial ageing in mice DW Trott, DR Machin, TTT Phuong, ALO Adeyemo, SI Bloom, ... The Journal of physiology 599 (16), 3973-3991, 2021 | 14 | 2021 |
Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction DR Machin, DW Trott, VR Gogulamudi, MT Islam, SI Bloom, H Vink, ... Geroscience 45 (4), 2351-2365, 2023 | 12 | 2023 |
Endothelial cell‐specific reduction in mTOR ameliorates age‐related arterial and metabolic dysfunction MT Islam, SA Hall, T Dutson, SI Bloom, RC Bramwell, J Kim, JR Tucker, ... Aging Cell, e14040, 2023 | 4 | 2023 |
Reduction of double-strand DNA break repair exacerbates vascular aging SI Bloom, JR Tucker, DR Machin, H Abdeahad, ALO Adeyemo, ... Aging (Albany NY) 15 (19), 9913, 2023 | 2 | 2023 |
Hemostatic responses to multiple bouts of firefighting activity: Female vs. male differences in a high demand, high performance occupation DL Smith, GP Horn, SJ Petruzzello, GG Freund, SI Bloom, B Fernhall International journal of environmental research and public health 19 (4), 2124, 2022 | 2 | 2022 |
Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice MT Islam, J Cai, S Allen, DG Moreno, SI Bloom, RC Bramwell, J Mitton, ... Arteriosclerosis, Thrombosis, and Vascular Biology 44 (5), 1101-1113, 2024 | 1 | 2024 |
Senolytics reduce endothelial cell DNA damage and telomere dysfunction in old age S Bloom, E Tuday, MT Islam, V Gogulamudi, L Lesniewski, A Donato Physiology 38 (S1), 5733289, 2023 | 1 | 2023 |
Aging results in endothelial cell telomere uncapping that induces senescence and physiological dysfunction SI Bloom, JR Tucker, Y Liu, H Abdeahad, DR Machin, TG Thomas, ... The FASEB Journal 36, 2022 | 1 | 2022 |
Endothelial Cell Specific Deletion of mTOR Ameliorates Age-Related Arterial and Metabolic Dysfunction T Islam, SA Hall, SI Bloom, RCC Bramwell, T Dutson, JR Tucker, J Kim, ... Circulation 144 (Suppl_1), A12952-A12952, 2021 | 1 | 2021 |