关注
Samuel I. Bloom
Samuel I. Bloom
Postdoctoral Fellow at Salk Institute
在 salk.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Mechanisms and consequences of endothelial cell senescence
SI Bloom, MT Islam, LA Lesniewski, AJ Donato
Nature Reviews Cardiology 20 (1), 38-51, 2023
1482023
Advanced age results in a diminished endothelial glycocalyx
DR Machin, SI Bloom, RA Campbell, TTT Phuong, PE Gates, ...
American Journal of Physiology-Heart and Circulatory Physiology 315 (3 …, 2018
1012018
A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes
LH Yuen, S Dana, Y Liu, SI Bloom, AG Thorsell, D Neri, AJ Donato, ...
Journal of the American Chemical Society 141 (13), 5169-5181, 2019
952019
The role of senescence, telomere dysfunction and shelterin in vascular aging
Y Liu, SI Bloom, AJ Donato
Microcirculation 26 (2), e12487, 2019
682019
Effects of a combined protein and antioxidant supplement on recovery of muscle function and soreness following eccentric exercise
SJ Ives, S Bloom, A Matias, N Morrow, N Martins, Y Roh, D Ebenstein, ...
Journal of the International Society of Sports Nutrition 14, 1-10, 2017
502017
Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress
RG Morgan, AE Walker, DW Trott, DR Machin, GD Henson, KD Reihl, ...
Journal of molecular and cellular cardiology 127, 74-82, 2019
302019
Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments
SI Bloom, Y Liu, JR Tucker, MT Islam, DR Machin, H Abdeahad, ...
Aging Cell 22 (8), e13875, 2023
182023
Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions
SI Bloom, JR Tucker, J Lim, TG Thomas, GJ Stoddard, LA Lesniewski, ...
Geroscience 44 (6), 2741-2755, 2022
182022
Firefighting induces acute inflammatory responses that are not relieved by aspirin in older firefighters
DL Smith, NMG Friedman, SI Bloom, WL Armero, BD Pence, MD Cook, ...
Journal of occupational and environmental medicine 61 (7), 617-622, 2019
172019
Implications of endothelial shear stress on systemic sclerosis vasculopathy and treatment
TM Frech, DR Machin, MA Murtaugh, GJ Stoddard, SI Bloom, JV Phibbs, ...
Clinical and experimental rheumatology 36 (Suppl 113), 175, 2018
172018
High‐fat diet induced obesity and age influence the telomere shelterin complex and telomerase gene expression in mouse adipose tissue
SI Bloom, A Tuluca, SJ Ives, TH Reynolds
Physiological reports 8 (11), e14461, 2020
152020
T cells mediate cell non‐autonomous arterial ageing in mice
DW Trott, DR Machin, TTT Phuong, ALO Adeyemo, SI Bloom, ...
The Journal of physiology 599 (16), 3973-3991, 2021
142021
Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction
DR Machin, DW Trott, VR Gogulamudi, MT Islam, SI Bloom, H Vink, ...
Geroscience 45 (4), 2351-2365, 2023
122023
Endothelial cell‐specific reduction in mTOR ameliorates age‐related arterial and metabolic dysfunction
MT Islam, SA Hall, T Dutson, SI Bloom, RC Bramwell, J Kim, JR Tucker, ...
Aging Cell, e14040, 2023
42023
Reduction of double-strand DNA break repair exacerbates vascular aging
SI Bloom, JR Tucker, DR Machin, H Abdeahad, ALO Adeyemo, ...
Aging (Albany NY) 15 (19), 9913, 2023
22023
Hemostatic responses to multiple bouts of firefighting activity: Female vs. male differences in a high demand, high performance occupation
DL Smith, GP Horn, SJ Petruzzello, GG Freund, SI Bloom, B Fernhall
International journal of environmental research and public health 19 (4), 2124, 2022
22022
Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice
MT Islam, J Cai, S Allen, DG Moreno, SI Bloom, RC Bramwell, J Mitton, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 44 (5), 1101-1113, 2024
12024
Senolytics reduce endothelial cell DNA damage and telomere dysfunction in old age
S Bloom, E Tuday, MT Islam, V Gogulamudi, L Lesniewski, A Donato
Physiology 38 (S1), 5733289, 2023
12023
Aging results in endothelial cell telomere uncapping that induces senescence and physiological dysfunction
SI Bloom, JR Tucker, Y Liu, H Abdeahad, DR Machin, TG Thomas, ...
The FASEB Journal 36, 2022
12022
Endothelial Cell Specific Deletion of mTOR Ameliorates Age-Related Arterial and Metabolic Dysfunction
T Islam, SA Hall, SI Bloom, RCC Bramwell, T Dutson, JR Tucker, J Kim, ...
Circulation 144 (Suppl_1), A12952-A12952, 2021
12021
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