Cardiac tissue engineering: state of the art MN Hirt, A Hansen, T Eschenhagen Circulation research 114 (2), 354-367, 2014 | 483 | 2014 |
Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology S Schaaf, A Shibamiya, M Mewe, A Eder, A Stöhr, MN Hirt, T Rau, ... PloS one 6 (10), e26397, 2011 | 433 | 2011 |
Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation MN Hirt, J Boeddinghaus, A Mitchell, S Schaaf, C Börnchen, C Müller, ... Journal of molecular and cellular cardiology 74, 151-161, 2014 | 397 | 2014 |
Human engineered heart tissue: analysis of contractile force I Mannhardt, K Breckwoldt, D Letuffe-Brenière, S Schaaf, H Schulz, ... Stem cell reports 7 (1), 29-42, 2016 | 389 | 2016 |
Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density MD Lemoine, I Mannhardt, K Breckwoldt, M Prondzynski, F Flenner, ... Scientific reports 7 (1), 5464, 2017 | 203 | 2017 |
Increased afterload induces pathological cardiac hypertrophy: a new in vitro model MN Hirt, NA Sörensen, LM Bartholdt, J Boeddinghaus, S Schaaf, A Eder, ... Basic research in cardiology 107, 1-16, 2012 | 187 | 2012 |
Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy J Viereck, A Bührke, A Foinquinos, S Chatterjee, JA Kleeberger, K Xiao, ... European heart journal 41 (36), 3462-3474, 2020 | 99 | 2020 |
Long noncoding RNA-enriched vesicles secreted by hypoxic cardiomyocytes drive cardiac fibrosis F Kenneweg, C Bang, K Xiao, CM Boulanger, X Loyer, S Mazlan, ... Molecular Therapy-Nucleic Acids 18, 363-374, 2019 | 99 | 2019 |
Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice A Stöhr, FW Friedrich, F Flenner, B Geertz, A Eder, S Schaaf, MN Hirt, ... Journal of molecular and cellular cardiology 63, 189-198, 2013 | 85 | 2013 |
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction DJ Trembinski, DI Bink, K Theodorou, J Sommer, A Fischer, A van Bergen, ... Nature communications 11 (1), 2039, 2020 | 77 | 2020 |
Glycoproteomics reveals decorin peptides with anti-myostatin activity in human atrial fibrillation J Barallobre-Barreiro, SK Gupta, A Zoccarato, R Kitazume-Taneike, ... Circulation 134 (11), 817-832, 2016 | 65 | 2016 |
Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia M Schäfer, CU Oeing, M Rohm, E Baysal-Temel, LH Lehmann, R Bauer, ... Molecular metabolism 5 (2), 67-78, 2016 | 65 | 2016 |
Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue-and sequencing-technology MN Hirt, T Werner, D Indenbirken, M Alawi, P Demin, AC Kunze, J Stenzig, ... Journal of molecular and cellular cardiology 81, 1-9, 2015 | 61 | 2015 |
General practitioners' adherence to chronic heart failure guidelines regarding medication: the GP-HF study MN Hirt, A Muttardi, TM Helms, H van den Bussche, T Eschenhagen Clinical Research in Cardiology 105, 441-450, 2016 | 54 | 2016 |
An important role for DNMT3A-mediated DNA methylation in cardiomyocyte metabolism and contractility A Madsen, G Höppner, J Krause, MN Hirt, SD Laufer, M Schweizer, ... Circulation 142 (16), 1562-1578, 2020 | 53 | 2020 |
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats J Stenzig, Y Schneeberger, A Löser, BS Peters, A Schaefer, RR Zhao, ... Journal of Molecular and Cellular Cardiology 120, 53-63, 2018 | 49 | 2018 |
DNA methylation in an engineered heart tissue model of cardiac hypertrophy: common signatures and effects of DNA methylation inhibitors J Stenzig, MN Hirt, A Löser, LM Bartholdt, JT Hensel, TR Werner, ... Basic research in cardiology 111, 1-14, 2016 | 41 | 2016 |
Analysis of tyrosine kinase inhibitor-mediated decline in contractile force in rat engineered heart tissue F Jacob, AY Yonis, F Cuello, P Luther, T Schulze, A Eder, T Streichert, ... PloS one 11 (2), e0145937, 2016 | 39 | 2016 |
Magnetics-based approach for fine-tuning afterload in engineered heart tissues ML Rodriguez, TR Werner, B Becker, T Eschenhagen, MN Hirt ACS biomaterials science & engineering 5 (7), 3663-3675, 2019 | 22 | 2019 |
Assessment of cardiotoxicity with stem cell-based strategies AMS Stoter, MN Hirt, J Stenzig, F Weinberger Clinical therapeutics 42 (10), 1892-1910, 2020 | 18 | 2020 |