| The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease JN van der Veen, JP Kennelly, S Wan, JE Vance, DE Vance, RL Jacobs Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (9), 1558-1572, 2017 | 1244 | 2017 |
| Aster proteins regulate the accessible cholesterol pool in the plasma membrane A Ferrari, C He, JP Kennelly, J Sandhu, X Xiao, X Chi, H Jiang, SG Young, ... Molecular and Cellular Biology 40 (19), e00255-20, 2020 | 57 | 2020 |
| Excess folic acid increases lipid storage, weight gain, and adipose tissue inflammation in high fat diet-fed rats KB Kelly, JP Kennelly, M Ordonez, R Nelson, K Leonard, S Stabler, ... Nutrients 8 (10), 594, 2016 | 57 | 2016 |
| Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis JP Kennelly, JN van der Veen, RC Nelson, KA Leonard, R Havinga, ... Journal of Lipid Research 59 (9), 1695-1708, 2018 | 40 | 2018 |
| Intestinal phospholipid disequilibrium initiates an ER stress response that drives goblet cell necroptosis and spontaneous colitis in mice JP Kennelly, S Carlin, T Ju, JN van der Veen, RC Nelson, J Buteau, ... Cellular and Molecular Gastroenterology and Hepatology 11 (4), 999-1021, 2021 | 37 | 2021 |
| Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis X Xiao, JP Kennelly, A Ferrari, BL Clifford, E Whang, Y Gao, K Qian, ... Nature metabolism 5 (1), 165-181, 2023 | 34 | 2023 |
| Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: post-translational repression of phosphatidylethanolamine N-methyltransferase is a … RL Jacobs, H Jiang, JP Kennelly, DJ Orlicky, RH Allen, SP Stabler, ... Molecular Genetics and Metabolism 120 (4), 325-336, 2017 | 23 | 2017 |
| Two-week isocaloric time-restricted feeding decreases liver inflammation without significant weight loss in obese mice with non-alcoholic fatty liver disease RB Wilson, R Zhang, YJ Chen, KM Peters, CG Sawyez, BG Sutherland, ... International journal of molecular sciences 21 (23), 9156, 2020 | 21 | 2020 |
| Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake A Ferrari, E Whang, X Xiao, JP Kennelly, B Romartinez-Alonso, JJ Mack, ... Science 382 (6671), eadf0966, 2023 | 20 | 2023 |
| The marine compound and elongation factor 1A1 inhibitor, didemnin B, provides benefit in western diet-induced non-alcoholic fatty liver disease RB Wilson, YJ Chen, BG Sutherland, CG Sawyez, R Zhang, T Woolnough, ... Pharmacological Research 161, 105208, 2020 | 18 | 2020 |
| Cholesterol transport to the endoplasmic reticulum JP Kennelly, P Tontonoz Cold Spring Harbor Perspectives in Biology 15 (2), a041263, 2023 | 16 | 2023 |
| Insufficient dietary choline aggravates disease severity in a mouse model of Citrobacter rodentium-induced colitis T Ju, JP Kennelly, RL Jacobs, BP Willing British Journal of Nutrition 125 (1), 50-61, 2021 | 14 | 2021 |
| Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking END Palladino, T Bernas, CD Green, C Weigel, SK Singh, CE Senkal, ... Proceedings of the National Academy of Sciences 119 (39), e2204396119, 2022 | 12 | 2022 |
| Aster-B–dependent estradiol synthesis protects female mice from diet-induced obesity X Xiao, JP Kennelly, AC Feng, L Cheng, B Romartinez-Alonso, A Bedard, ... The Journal of Clinical Investigation 134 (4), 2024 | 7 | 2024 |
| Mechanosensitive membrane domains regulate calcium entry in arterial endothelial cells to protect against inflammation SG Hong, JW Ashby, JP Kennelly, M Wu, M Steel, E Chattopadhyay, ... The Journal of Clinical Investigation, 2024 | 5 | 2024 |
| Hepatic GATA4 regulates cholesterol and triglyceride homeostasis in collaboration with LXRs L Bideyan, ML Rodríguez, C Priest, JP Kennelly, Y Gao, A Ferrari, ... Genes & Development 36 (21-24), 1129-1144, 2022 | 4 | 2022 |
| De novo phosphatidylcholine synthesis in the small intestinal epithelium is required for normal dietary lipid handling and maintenance of the mucosal barrier S Carlin, JP Kennelly, H Fedoruk, A Quiroga, KA Leonard, R Nelson, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2022 | 4 | 2022 |
| Low MBOAT7 expression, a genetic risk for MASH, promotes a pro-fibrotic pathway involving hepatocyte TAZ upregulation MP Moore, X Wang, JP Kennelly, H Shi, Y Ishino, K Kano, J Aoki, ... Hepatology, 10.1097, 2024 | 2 | 2024 |
| Polarized mechanosensitive signaling domains protect arterial endothelial cells against inflammation SG Hong, JW Ashby, JP Kennelly, M Wu, E Chattopadhyay, R Foreman, ... bioRxiv, 2023.05. 26.542500, 2023 | 2 | 2023 |
| Lipid-and protein-directed photosensitizer proximity labeling captures the cholesterol interactome AP Becker, E Biletch, JP Kennelly, AR Julio, M Villaneuva, RT Nagari, ... bioRxiv, 2024 | 1 | 2024 |
