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Carla Casu
Carla Casu
The Children's Hospital of Philadelphia
在 chop.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin
S Aschemeyer, B Qiao, D Stefanova, EV Valore, AC Sek, TA Ruwe, ...
Blood, The Journal of the American Society of Hematology 131 (8), 899-910, 2018
3172018
Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia
P Ramos, C Casu, S Gardenghi, L Breda, BJ Crielaard, E Guy, ...
Nature medicine 19 (4), 437-445, 2013
2532013
Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice
S Guo, C Casu, S Gardenghi, S Booten, M Aghajan, R Peralta, A Watt, ...
The Journal of clinical investigation 123 (4), 1531-1541, 2013
2512013
Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera
C Casu, PR Oikonomidou, H Chen, V Nandi, Y Ginzburg, P Prasad, ...
Blood, The Journal of the American Society of Hematology 128 (2), 265-276, 2016
1502016
FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis
LM Coe, SV Madathil, C Casu, B Lanske, S Rivella, D Sitara
Journal of Biological Chemistry 289 (14), 9795-9810, 2014
1482014
Hepcidin agonists as therapeutic tools
C Casu, E Nemeth, S Rivella
Blood, The Journal of the American Society of Hematology 131 (16), 1790-1794, 2018
1452018
DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia
LKM Lam, S Murphy, D Kokkinaki, A Venosa, S Sherrill-Mix, C Casu, ...
Science translational medicine 13 (616), eabj1008, 2021
1412021
The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice
G Casanovas, MV Spasić, C Casu, S Rivella, J Strelau, K Unsicker, ...
Haematologica 98 (3), 444, 2013
1302013
Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus
S Gardenghi, TM Renaud, A Meloni, C Casu, BJ Crielaard, LM Bystrom, ...
Blood, The Journal of the American Society of Hematology 123 (8), 1137-1145, 2014
1152014
Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients
L Breda, C Casu, S Gardenghi, N Bianchi, L Cartegni, M Narla, ...
PloS one 7 (3), e32345, 2012
1102012
Combination of Tmprss6-ASO and the iron chelator deferiprone improves erythropoiesis and reduces iron overload in a mouse model of beta-thalassemia intermedia
C Casu, M Aghajan, PR Oikonomidou, S Guo, BP Monia, S Rivella
Haematologica 101 (1), e8, 2016
812016
Klotho deficiency disrupts hematopoietic stem cell development and erythropoiesis
SV Madathil, LM Coe, C Casu, D Sitara
The American journal of pathology 184 (3), 827-841, 2014
662014
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3
SR Pasricha, PJ Lim, TL Duarte, C Casu, D Oosterhuis, ...
Nature communications 8 (1), 403, 2017
632017
Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis
P Ramos, E Guy, N Chen, CC Proenca, S Gardenghi, C Casu, A Follenzi, ...
Blood, The Journal of the American Society of Hematology 117 (4), 1379-1389, 2011
602011
Lack of Gdf11 does not improve anemia or prevent the activity of RAP-536 in a mouse model of β-thalassemia
A Guerra, PR Oikonomidou, S Sinha, J Zhang, V Lo Presti, CR Hamilton, ...
Blood, The Journal of the American Society of Hematology 134 (6), 568-572, 2019
562019
Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult β-thalassemia major
C Casu, R Chessa, A Liu, R Gupta, H Drakesmith, R Fleming, ...
Haematologica 105 (7), 1835, 2020
482020
Lobe specificity of iron binding to transferrin modulates murine erythropoiesis and iron homeostasis
NL Parrow, Y Li, M Feola, A Guerra, C Casu, P Prasad, L Mammen, F Ali, ...
Blood, The Journal of the American Society of Hematology 134 (17), 1373-1384, 2019
412019
Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome
RB Nowak, J Papoin, DS Gokhin, C Casu, S Rivella, JM Lipton, L Blanc, ...
Blood, The Journal of the American Society of Hematology 130 (9), 1144-1155, 2017
402017
Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity
C Casu, M Pettinato, A Liu, M Aghajan, V Lo Presti, MR Lidonnici, ...
Blood, The Journal of the American Society of Hematology 136 (17), 1968-1979, 2020
382020
Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of β-thalassemia intermedia and major
C Casu, VL Presti, PR Oikonomidou, L Melchiori, O Abdulmalik, P Ramos, ...
Haematologica 103 (2), e46, 2018
372018
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