Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development P Kucharzewska, HC Christianson, JE Welch, KJ Svensson, E Fredlund, ... Proceedings of the National Academy of Sciences 110 (18), 7312-7317, 2013 | 978 | 2013 |
Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity HC Christianson, KJ Svensson, TH van Kuppevelt, JP Li, M Belting Proceedings of the National Academy of Sciences 110 (43), 17380-17385, 2013 | 944 | 2013 |
Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch P Cohen, JD Levy, Y Zhang, A Frontini, DP Kolodin, KJ Svensson, JC Lo, ... Cell 156 (1-2), 304-316, 2014 | 921 | 2014 |
Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis RR Rao, JZ Long, JP White, KJ Svensson, J Lou, I Lokurkar, ... Cell 157 (6), 1279-1291, 2014 | 903 | 2014 |
Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1 KJ Svensson, HC Christianson, A Wittrup, E Bourseau-Guilmain, ... Journal of Biological Chemistry 288 (24), 17713-17724, 2013 | 745 | 2013 |
A smooth muscle-like origin for beige adipocytes JZ Long, KJ Svensson, L Tsai, X Zeng, HC Roh, X Kong, RR Rao, J Lou, ... Cell metabolism 19 (5), 810-820, 2014 | 493 | 2014 |
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells KJ Svensson, P Kucharzewska, HC Christianson, S Sköld, T Löfstedt, ... Proceedings of the National Academy of Sciences 108 (32), 13147-13152, 2011 | 345 | 2011 |
The secreted enzyme PM20D1 regulates lipidated amino acid uncouplers of mitochondria JZ Long, KJ Svensson, LA Bateman, H Lin, T Kamenecka, IA Lokurkar, ... Cell 166 (2), 424-435, 2016 | 219 | 2016 |
A secreted Slit2 fragment regulates adipose tissue thermogenesis and metabolic function KJ Svensson, JZ Long, MP Jedrychowski, P Cohen, JC Lo, S Serag, S Kir, ... Cell metabolism 23 (3), 454-466, 2016 | 147 | 2016 |
Metastasis stimulation by hypoxia and acidosis-induced extracellular lipid uptake is mediated by proteoglycan-dependent endocytosis JA Menard, HC Christianson, P Kucharzewska, E Bourseau-Guilmain, ... Cancer research 76 (16), 4828-4840, 2016 | 99 | 2016 |
Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery A Wittrup, SH Zhang, KJ Svensson, P Kucharzewska, MC Johansson, ... Proceedings of the National Academy of Sciences 107 (30), 13342-13347, 2010 | 81 | 2010 |
Dermatan sulfate is involved in the tumorigenic properties of esophagus squamous cell carcinoma MA Thelin, KJ Svensson, X Shi, M Bagher, J Axelsson, A Isinger-Ekstrand, ... Cancer research 72 (8), 1943-1952, 2012 | 73 | 2012 |
Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis Z Jiang, M Zhao, L Voilquin, Y Jung, MA Aikio, T Sahai, FY Dou, ... Cell Metabolism 33 (9), 1836-1852. e11, 2021 | 67 | 2021 |
Chondroitin sulfate expression predicts poor outcome in breast cancer KJ Svensson, HC Christianson, P Kucharzewska, V Fagerström, ... International journal of oncology 39 (6), 1421-1428, 2011 | 58 | 2011 |
Exosome and microvesicle mediated phene transfer in mammalian cells HC Christianson, KJ Svensson, M Belting Seminars in cancer biology 28, 31-38, 2014 | 56 | 2014 |
Ablation of PM20D1 reveals N-acyl amino acid control of metabolism and nociception JZ Long, AM Roche, CA Berdan, SM Louie, AJ Roberts, KJ Svensson, ... Proceedings of the National Academy of Sciences 115 (29), E6937-E6945, 2018 | 54 | 2018 |
Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine … KJ Svensson, JE Welch, P Kucharzewska, P Bengtson, M Bjurberg, ... Cancer research 68 (22), 9291-9301, 2008 | 54 | 2008 |
Mitochondria-rich extracellular vesicles rescue patient-specific cardiomyocytes from doxorubicin injury: insights into the SENECA trial CG O’Brien, MO Ozen, G Ikeda, E Vaskova, JH Jung, N Bayardo, ... Cardio Oncology 3 (3), 428-440, 2021 | 47 | 2021 |
Standardization and utilization of biobank resources in clinical protein science with examples of emerging applications G Marko-Varga, A Vegvari, C Welinder, H Lindberg, M Rezeli, G Edula, ... Journal of Proteome Research 11 (11), 5124-5134, 2012 | 47 | 2012 |
The polyamines regulate endothelial cell survival during hypoxic stress through PI3K/AKT and MCL-1 P Kucharzewska, JE Welch, KJ Svensson, M Belting Biochemical and biophysical research communications 380 (2), 413-418, 2009 | 46 | 2009 |