RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features VI Gaidzik, V Teleanu, E Papaemmanuil, D Weber, P Paschka, J Hahn, ... Leukemia 30 (11), 2160-2168, 2016 | 310 | 2016 |
Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish K Reichwald, A Petzold, P Koch, BR Downie, N Hartmann, S Pietsch, ... Cell 163 (6), 1527-1538, 2015 | 282 | 2015 |
Lifestyle impacts on the aging‐associated expression of biomarkers of DNA damage and telomere dysfunction in human blood Z Song, G Von Figura, Y Liu, JM Kraus, C Torrice, P Dillon, ... Aging cell 9 (4), 607-615, 2010 | 197 | 2010 |
Electrocardiographic and cardiac magnetic resonance imaging parameters as predictors of a worse outcome in patients with idiopathic dilated cardiomyopathy V Hombach, N Merkle, J Torzewski, JM Kraus, M Kunze, O Zimmermann, ... European heart journal 30 (16), 2011-2018, 2009 | 131 | 2009 |
Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals S Schwörer, F Becker, C Feller, AH Baig, U Köber, H Henze, JM Kraus, ... Nature 540 (7633), 428-432, 2016 | 127 | 2016 |
Early relapse in all is identified by time to leukemia in NOD/SCID mice and is characterized by a gene signature involving survival pathways LH Meyer, SM Eckhoff, M Queudeville, JM Kraus, M Giordan, J Stursberg, ... Cancer cell 19 (2), 206-217, 2011 | 123 | 2011 |
VennMaster: area-proportional Euler diagrams for functional GO analysis of microarrays HA Kestler, A Müller, JM Kraus, M Buchholz, TM Gress, H Liu, DW Kane, ... BMC bioinformatics 9 (1), 67, 2008 | 123 | 2008 |
Significantly improved precision of cell migration analysis in time-lapse video microscopy through use of a fully automated tracking system J Huth, M Buchholz, J Kraus, M Schmucker, G Von Wichert, D Krndija, ... BMC cell biology 11 (1), 24, 2010 | 120 | 2010 |
Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation SF Katz, A Lechel, AC Obenauf, Y Begus–Nahrmann, JM Kraus, ... Gastroenterology 142 (5), 1229-1239. e3, 2012 | 113 | 2012 |
Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage S Tao, D Tang, Y Morita, T Sperka, O Omrani, A Lechel, V Sakk, J Kraus, ... The EMBO Journal, e201490700, 2015 | 94 | 2015 |
Central nervous system involvement in acute lymphoblastic leukemia is mediated by vascular endothelial growth factor V Münch, L Trentin, J Herzig, S Demir, F Seyfried, JM Kraus, HA Kestler, ... Blood 130 (5), 643-654, 2017 | 84 | 2017 |
Telomerase abrogates aneuploidy‐induced telomere replication stress, senescence and cell depletion JK Meena, A Cerutti, C Beichler, Y Morita, C Bruhn, M Kumar, JM Kraus, ... The EMBO journal 34 (10), 1371-1384, 2015 | 80 | 2015 |
Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis Y Begus-Nahrmann, D Hartmann, J Kraus, P Eshraghi, A Scheffold, ... The Journal of clinical investigation 122 (6), 2283-2288, 2012 | 80 | 2012 |
PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways BP Kaistha, H Lorenz, H Schmidt, B Sipos, M Pawlak, B Gierke, R Kreider, ... Cancer research 76 (1), 96-107, 2016 | 70 | 2016 |
Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation Z Chen, EM Amro, F Becker, M Hölzer, SMM Rasa, SN Njeru, B Han, ... Journal of Experimental Medicine 216 (1), 152-175, 2019 | 68 | 2019 |
TimeLapseAnalyzer: Multi-target analysis for live-cell imaging and time-lapse microscopy J Huth, M Buchholz, JM Kraus, K Mølhave, C Gradinaru, G Wichert, ... Computer methods and programs in biomedicine 104 (2), 227-234, 2011 | 63 | 2011 |
Protein kinase D1, reduced in human pancreatic tumors, increases secretion of small extracellular vesicles from cancer cells that promote metastasis to lung in mice M Armacki, S Polaschek, M Waldenmaier, M Morawe, C Ruhland, ... Gastroenterology 159 (3), 1019-1035. e22, 2020 | 62 | 2020 |
Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer J Gout, L Perkhofer, M Morawe, F Arnold, M Ihle, S Biber, S Lange, ... Gut 70 (4), 743-760, 2021 | 61 | 2021 |
Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex A Kleger, PU Mahaddalkar, SF Katz, A Lechel, JY Joo, K Loya, Q Lin, ... Gastroenterology 142 (4), 907-917, 2012 | 61 | 2012 |
Long-lived rodents reveal signatures of positive selection in genes associated with lifespan A Sahm, M Bens, K Szafranski, S Holtze, M Groth, M Görlach, ... PLoS genetics 14 (3), e1007272, 2018 | 57 | 2018 |