Antinociceptive effects of St. John's wort, Harpagophytum procumbens extract and Grape seed proanthocyanidins extract in mice S Uchida, K Hirai, J Hatanaka, J Hanato, K Umegaki, S Yamada Biological and Pharmaceutical Bulletin 31 (2), 240-245, 2008 | 99 | 2008 |
Augmented renal clearance in patients with febrile neutropenia is associated with increased risk for subtherapeutic concentrations of vancomycin K Hirai, H Ishii, T Shimoshikiryo, T Shimomura, D Tsuji, K Inoue, T Kadoiri, ... Therapeutic Drug Monitoring 38 (6), 706-710, 2016 | 77 | 2016 |
Combined assessment of serum periostin and YKL-40 may identify asthma-COPD overlap T Shirai, K Hirai, Y Gon, S Maruoka, K Mizumura, M Hikichi, C Holweg, ... The Journal of Allergy and Clinical Immunology: In Practice 7 (1), 134-145. e1, 2019 | 64 | 2019 |
Augmented renal clearance in pediatric patients with febrile neutropenia associated with vancomycin clearance. K Hirai, S Ihara, A Kinae, K Ikegaya, M Suzuki, K Hirano, K Itoh Therapeutic Drug Monitoring 38 (3), 393-397, 2016 | 62 | 2016 |
Simultaneous microdetermination of bosentan, ambrisentan, sildenafil, and tadalafil in plasma using liquid chromatography/tandem mass spectrometry for pediatric patients with … Y Yokoyama, M Tomatsuri, H Hayashi, K Hirai, Y Ono, Y Yamada, ... Journal of pharmaceutical and biomedical analysis 89, 227-232, 2014 | 46 | 2014 |
Role of type2 inflammatory biomarkers in chronic obstructive pulmonary disease K Oishi, K Matsunaga, T Shirai, K Hirai, Y Gon Journal of Clinical Medicine 9 (8), 2670, 2020 | 41 | 2020 |
The effect of CYP4F2, VKORC1 and CYP2C9 in influencing coumarin dose. A single patient data meta‐analysis in more than 15,000 individuals E Danese, S Raimondi, M Montagnana, A Tagetti, T Langaee, P Borgiani, ... Clinical Pharmacology & Therapeutics, 2018 | 41 | 2018 |
A clustering approach to identify and characterize the asthma and chronic obstructive pulmonary disease overlap phenotype K Hirai, T Shirai, M Suzuki, T Akamatsu, T Suzuki, I Hayashi, A Yamamoto, ... Clinical & Experimental Allergy 47 (11), 1374-1382, 2017 | 37 | 2017 |
Circulating microRNA‐15b‐5p as a biomarker for asthma‐COPD overlap K Hirai, T Shirai, T Shimoshikiryo, M Ueda, Y Gon, S Maruoka, K Itoh Allergy, 2020 | 32 | 2020 |
Drug-related genetic polymorphisms affecting severe chemotherapy-induced neutropenia in breast cancer patients: a hospital-based observational study D Tsuji, M Ikeda, K Yamamoto, H Nakamori, YI Kim, Y Kawasaki, A Otake, ... Medicine 95 (44), e5151, 2016 | 31 | 2016 |
Risk factors for hypernatremia in patients with short-and long-term tolvaptan treatment K Hirai, T Shimomura, H Moriwaki, H Ishii, T Shimoshikiryo, D Tsuji, ... European Journal of Clinical Pharmacology 72 (10), 1177–1183, 2016 | 31 | 2016 |
Influence of CYP4F2 polymorphisms and plasma vitamin K levels on warfarin sensitivity in Japanese pediatric patients K Hirai, H Hayashi, Y Ono, K Izumiya, M Tanaka, T Suzuki, T Sakamoto, ... Drug metabolism and pharmacokinetics 28 (2), 132-137, 2012 | 30 | 2012 |
Validation of a nomogram for achieving target trough concentration of vancomycin: accuracy in patients with augmented renal function H Ishii, K Hirai, K Sugiyama, E Nakatani, M Kimura, K Itoh Therapeutic Drug Monitoring 40 (6), 693-698, 2018 | 28 | 2018 |
Factors that influence the pharmacokinetics of lamotrigine in Japanese patients with epilepsy K Inoue, Y Yamamoto, E Suzuki, T Takahashi, A Umemura, Y Takahashi, ... European journal of clinical pharmacology 72 (5), 555-562, 2016 | 24 | 2016 |
Mucus plugs and small airway dysfunction in asthma, COPD, and asthma-COPD overlap K Tamura, T Shirai, K Hirai, H Nakayasu, S Takahashi, Y Kishimoto, ... Allergy, Asthma & Immunology Research 14 (2), 196, 2022 | 23 | 2022 |
Influence of ABCB1 and ABCG2 polymorphisms on the antiemetic efficacy in patients with cancer receiving cisplatin-based chemotherapy: a TRIPLE pharmacogenomics study D Tsuji, M Yokoi, K Suzuki, T Daimon, M Nakao, H Ayuhara, Y Kogure, ... The pharmacogenomics journal 17 (5), 435-440, 2017 | 23 | 2017 |
Plasma vitamin K concentrations depend on CYP4F2 polymorphism and influence on anticoagulation in Japanese patients with warfarin therapy K Hirai, Y Yamada, H Hayashi, M Tanaka, K Izumiya, M Suzuki, ... Thrombosis research 135 (5), 861-866, 2015 | 23 | 2015 |
Chemotherapy-induced neutropenia as a prognostic factor in patients with metastatic pancreatic cancer treated with gemcitabine A Otake, D Tsuji, K Taku, Y Kawasaki, M Yokoi, H Nakamori, M Osada, ... European Journal of Clinical Pharmacology 73, 1033-1039, 2017 | 19 | 2017 |
Association between (CCTTT)n repeat polymorphism in NOS2 promoter and asthma exacerbations Keita Hirai, Toshihiro Shirai, Masayuki Suzuki, Tatsuki Shimomura, Kunihiko Itoh Journal of Allergy and Clinical Immunology 142 (2), 663–665.e3, 2018 | 18 | 2018 |
Oscillometry improves earlier than spirometry after benralizumab initiation in severe asthma T Shirai, T Akamatsu, K Hirai, H Watanabe, K Tamura, Y Kishimoto, ... Allergy 75 (10), 2678-2680, 2020 | 17 | 2020 |