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David C. Leitch
David C. Leitch
在 uvic.ca 的电子邮件经过验证 - 首页
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Chiral neutral zirconium amidate complexes for the asymmetric hydroamination of alkenes
MC Wood, DC Leitch, CS Yeung, JA Kozak, LL Schafer
Angewandte Chemie International Edition 46 (3), 354-358, 2007
3602007
The evolution of high-throughput experimentation in pharmaceutical development and perspectives on the future
SM Mennen, C Alhambra, CL Allen, M Barberis, S Berritt, TA Brandt, ...
Organic Process Research & Development 23 (6), 1213-1242, 2019
3592019
Intramolecular Hydroamination of Unactived Olefins with Ti(NMe2)4 as a Precatalyst
JA Bexrud, JD Beard, DC Leitch, LL Schafer
Organic Letters 7 (10), 1959-1962, 2005
2542005
Selective C− H activation α to primary amines. Bridging metallaaziridines for catalytic, intramolecular α-alkylation
JA Bexrud, P Eisenberger, DC Leitch, PR Payne, LL Schafer
Journal of the American Chemical Society 131 (6), 2116-2118, 2009
2012009
Broadening the scope of group 4 hydroamination catalysis using a tethered ureate ligand
DC Leitch, PR Payne, CR Dunbar, LL Schafer
Journal of the American Chemical Society 131 (51), 18246-18247, 2009
2002009
An Easy‐To‐Use, Regioselective, and Robust Bis (amidate) Titanium Hydroamination Precatalyst: Mechanistic and Synthetic Investigations toward the Preparation of …
Z Zhang, DC Leitch, M Lu, BO Patrick, LL Schafer
Chemistry–A European Journal 13 (7), 2012-2022, 2007
1362007
Mechanistic Elucidation of Intramolecular Aminoalkene Hydroamination Catalyzed by a Tethered Bis (ureate) Complex: Evidence for Proton-Assisted C–N Bond Formation at Zirconium
DC Leitch, RH Platel, LL Schafer
Journal of the American Chemical Society 133 (39), 15453-15463, 2011
1082011
Bis (amidate) bis (amido) titanium complex: a regioselective intermolecular alkyne hydroamination catalyst
JCH Yim, JA Bexrud, RO Ayinla, DC Leitch, LL Schafer
The Journal of Organic Chemistry 79 (5), 2015-2028, 2014
982014
The power and accessibility of high-throughput methods for catalysis research
CL Allen, DC Leitch, MS Anson, MA Zajac
Nature Catalysis 2 (1), 2-4, 2019
882019
Beyond bioisosteres: divergent synthesis of azabicyclohexanes and cyclobutenyl amines from bicyclobutanes
K Dhake, KJ Woelk, J Becica, A Un, SE Jenny, DC Leitch
Angewandte Chemie 134 (27), e202204719, 2022
772022
Upgrading light hydrocarbons via tandem catalysis: a dual homogeneous Ta/Ir system for alkane/alkene coupling
DC Leitch, YC Lam, JA Labinger, JE Bercaw
Journal of the American Chemical Society 135 (28), 10302-10305, 2013
752013
A palladium-catalysed multicomponent coupling approach to conjugated poly (1, 3-dipoles) and polyheterocycles
DC Leitch, LV Kayser, ZY Han, AR Siamaki, EN Keyzer, A Gefen, ...
Nature Communications 6 (1), 7411, 2015
682015
Isolation of catalytic intermediates in hydroamination reactions: insertion of internal alkynes into a zirconium–amido bond
DC Leitch, CS Turner, LL Schafer
Angewandte Chemie International Edition 49 (36), 6382-6386, 2010
682010
Mechanistic Insight Enables Practical, Scalable, Room Temperature Chan–Lam N-Arylation of N-Aryl Sulfonamides
JC Vantourout, L Li, E Bendito-Moll, S Chabbra, K Arrington, BE Bode, ...
ACS Catalysis 8 (10), 9560-9566, 2018
672018
Development and Cycloaddition Reactivity of a New Class of Pyridine‐Based Mesoionic 1, 3‐Dipole
H Erguven, DC Leitch, EN Keyzer, BA Arndtsen
Angewandte Chemie 129 (22), 6174-6178, 2017
412017
Convergent synthesis of the NS5B inhibitor GSK8175 enabled by transition metal catalysis
K Arrington, GA Barcan, NA Calandra, GA Erickson, L Li, L Liu, MG Nilson, ...
The Journal of Organic Chemistry 84 (8), 4680-4694, 2018
342018
Scope and mechanism of homogeneous tantalum/iridium tandem catalytic alkane/alkene upgrading using sacrificial hydrogen acceptors
DC Leitch, JA Labinger, JE Bercaw
Organometallics 33 (13), 3353-3365, 2014
342014
N, O‐Chelates of Group 4 Metals: Contrasting the Use of Amidates and Ureates in the Synthesis of Metal Dichlorides
DC Leitch, JD Beard, RK Thomson, VA Wright, BO Patrick, LL Schafer
European Journal of Inorganic Chemistry 2009 (18), 2691-2701, 2009
342009
Zirconium Alkyl Complexes Supported by Ureate Ligands: Synthesis, Characterization, and Precursors to Metal− Element Multiple Bonds
DC Leitch, LL Schafer
Organometallics 29 (21), 5162-5172, 2010
312010
Development and scale-up of continuous electrocatalytic hydrogenation of functionalized nitro arenes, nitriles, and unsaturated aldehydes
JD Egbert, EC Thomsen, SA O’Neill-Slawecki, DM Mans, DC Leitch, ...
Organic Process Research & Development 23 (9), 1803-1812, 2019
302019
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