| A selective gut bacterial bile salt hydrolase alters host metabolism L Yao, SC Seaton, S Ndousse-Fetter, AA Adhikari, N DiBenedetto, ... Elife 7, e37182, 2018 | 238 | 2018 |
| A microbial metabolite remodels the gut-liver axis following bariatric surgery SN Chaudhari, JN Luo, DA Harris, H Aliakbarian, L Yao, D Paik, ... Cell host & microbe 29 (3), 408-424. e7, 2021 | 112 | 2021 |
| Development of a covalent inhibitor of gut bacterial bile salt hydrolases AA Adhikari, TCM Seegar, SB Ficarro, MD McCurry, D Ramachandran, ... Nature chemical biology 16 (3), 318-326, 2020 | 99 | 2020 |
| Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis C Pedicone, S Fernandes, OM Dungan, SM Dormann, DR Viernes, ... Journal of cell science 133 (5), jcs238030, 2020 | 57 | 2020 |
| A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteria L Yao, GD D’Agostino, J Park, S Hang, AA Adhikari, Y Zhang, W Li, ... Nature microbiology 7 (9), 1404-1418, 2022 | 46 | 2022 |
| Lewis Acid Catalyzed Displacement of Trichloroacetimidates in the Synthesis of Functionalized Pyrroloindolines AA Adhikari, JD Chisholm Organic letters 18 (16), 4100-4103, 2016 | 35 | 2016 |
| A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases AA Adhikari, D Ramachandran, SN Chaudhari, CE Powell, W Li, ... ACS chemical biology 16 (8), 1401-1412, 2021 | 34 | 2021 |
| Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury DK Li, SN Chaudhari, Y Lee, M Sojoodi, AA Adhikari, L Zukerberg, ... Science Advances 8 (34), eabo2794, 2022 | 30 | 2022 |
| Synthesis and initial evaluation of quinoline-based inhibitors of the SH2-containing inositol 5′-phosphatase (SHIP) CM Russo, AA Adhikari, DR Wallach, S Fernandes, AN Balch, WG Kerr, ... Bioorganic & medicinal chemistry letters 25 (22), 5344-5348, 2015 | 29 | 2015 |
| Rearrangement of benzylic trichloroacetimidates to benzylic trichloroacetamides AA Adhikari, T Suzuki, RT Gilbert, MR Linaburg, JD Chisholm The Journal of organic chemistry 82 (7), 3982-3989, 2017 | 25 | 2017 |
| Convenient formation of diphenylmethyl esters using diphenylmethyl trichloroacetimidate AA Adhikari, JP Shah, KT Howard, CM Russo, DR Wallach, MR Linaburg, ... Synlett 25 (02), 283-287, 2014 | 22 | 2014 |
| Ester formation via symbiotic activation utilizing trichloroacetimidate electrophiles NS Mahajani, RIL Meador, TJ Smith, SE Canarelli, AA Adhikari, JP Shah, ... The Journal of organic chemistry 84 (12), 7871-7882, 2019 | 19 | 2019 |
| Synthesis of 3, 3′-Disubstituted Indolenines Utilizing the Lewis Acid Catalyzed Alkylation of 2, 3-Disubstituted Indoles with Trichloroacetimidates AA Adhikari, L Radal, JD Chisholm Synlett 28 (17), 2335-2339, 2017 | 12 | 2017 |
| Dialkylation of indoles with trichloroacetimidates to access 3, 3-disubstituted indolenines T Suzuki, NA Mate, AA Adhikari, JD Chisholm Molecules 24 (22), 4143, 2019 | 3 | 2019 |
| N1-Benzyl Tryptamine Pan-SHIP1/2 Inhibitors: Synthesis and Preliminary Biological Evaluation as Anti-Tumor Agents S Fernandes, ST Meyer, JP Shah, AA Adhikari, WG Kerr, JD Chisholm Molecules 27 (23), 8451, 2022 | 2 | 2022 |
| Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases AA Adhikari, TC Seegar, SB Ficarro, MD McCurry, D Ramachandran, ... bioRxiv, 640086, 2019 | 1 | 2019 |
| Small molecule modulators of gut bacterial bile acid metabolism AS Devlin, A Adhikari US Patent App. 17/610,037, 2022 | | 2022 |
| Bile salt hydrolases deplete conjugated bile acids and erode gut barrier integrity in non-alcoholic steatohepatitis DK Li, SN Chaudhari, M Sojoodi, Y Lee, AA Adhikari, Z Zhuo, L Zukerberg, ... bioRxiv, 2021.03. 24.436896, 2021 | | 2021 |
| Small molecule modulators of gut bacterial bile acid metabolism AS Devlin, A ADHIKARI | | 2020 |
| Selective Friedel-Crafts alkylation of indoles with trichloroacetimidates T Suzuki, A Adhikari, J Chisholm ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
A. Sloan DevlinAssociate Professor, Biological Chemistry and Molecular Pharmacology, Harvard Medical School在 hms.harvard.edu 的电子邮件经过验证
