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Xu Xiao
Xu Xiao
在 uky.edu 的电子邮件经过验证 - 首页
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Aster proteins facilitate nonvesicular plasma membrane to ER cholesterol transport in mammalian cells
J Sandhu, S Li, L Fairall, SG Pfisterer, JE Gurnett, X Xiao, TA Weston, ...
Cell 175 (2), 514-529. e20, 2018
2472018
Cholesterol modification of smoothened is required for hedgehog signaling
X Xiao, JJ Tang, C Peng, Y Wang, L Fu, ZP Qiu, Y Xiong, LF Yang, ...
Molecular cell 66 (1), 154-162. e10, 2017
2242017
SREBP: a novel therapeutic target
X Xiao, BL Song
Acta Biochim Biophys Sin 45 (1), 2-10, 2013
1652013
Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway
L Ding, J Li, B Song, XU Xiao, B Zhang, M Qi, W Huang, LI Yang, Z Wang
Toxicology and applied pharmacology 304, 99-109, 2016
1352016
Emodin improves lipid and glucose metabolism in high fat diet-induced obese mice through regulating SREBP pathway
J Li, L Ding, B Song, X Xiao, M Qi, Q Yang, Q Yang, X Tang, Z Wang, ...
European journal of pharmacology 770, 99-109, 2016
1002016
Andrographolide prevents high-fat diet–induced obesity in C57BL/6 mice by suppressing the sterol regulatory element-binding protein pathway
L Ding, J Li, B Song, X Xiao, W Huang, B Zhang, X Tang, M Qi, Q Yang, ...
Journal of Pharmacology and Experimental Therapeutics 351 (2), 474-483, 2014
832014
Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins
QD Zhou, X Chi, MS Lee, WY Hsieh, JJ Mkrtchyan, AC Feng, C He, ...
Nature immunology 21 (7), 746-755, 2020
802020
Aster proteins regulate the accessible cholesterol pool in the plasma membrane
A Ferrari, C He, JP Kennelly, J Sandhu, X Xiao, X Chi, H Jiang, SG Young, ...
Molecular and Cellular Biology 40 (19), e00255-20, 2020
572020
CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization
K Qian, MJ Tol, J Wu, LF Uchiyama, X Xiao, L Cui, AH Bedard, TA Weston, ...
Nature 613 (7942), 160-168, 2023
342023
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis
X Xiao, JP Kennelly, A Ferrari, BL Clifford, E Whang, Y Gao, K Qian, ...
Nature metabolism 5 (1), 165-181, 2023
342023
Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms
X Xiao, Y Kim, B Romartinez-Alonso, K Sirvydis, DS Ory, JWR Schwabe, ...
Proceedings of the National Academy of Sciences 118 (2), e2024149118, 2021
322021
A cancer cell–intrinsic GOT2–PPARδ axis suppresses antitumor immunity
J Abrego, H Sanford-Crane, C Oon, X Xiao, CB Betts, D Sun, S Nagarajan, ...
Cancer discovery 12 (10), 2414-2433, 2022
292022
Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase
SY Jiang, JJ Tang, X Xiao, W Qi, S Wu, C Jiang, J Hong, J Xu, BL Song, ...
PLoS Genetics 15 (7), e1008289, 2019
252019
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake
A Ferrari, E Whang, X Xiao, JP Kennelly, B Romartinez-Alonso, JJ Mack, ...
Science 382 (6671), eadf0966, 2023
202023
Therapeutic IDOL reduction ameliorates amyloidosis and improves cognitive function in APP/PS1 mice
J Gao, R Littman, G Diamante, X Xiao, IS Ahn, X Yang, TA Cole, ...
Molecular and Cellular Biology 40 (8), e00518-19, 2020
102020
Aster-B–dependent estradiol synthesis protects female mice from diet-induced obesity
X Xiao, JP Kennelly, AC Feng, L Cheng, B Romartinez-Alonso, A Bedard, ...
The Journal of Clinical Investigation 134 (4), 2024
62024
Brap regulates liver morphology and hepatocyte turnover via modulation of the Hippo pathway
C Priest, RT Nagari, L Bideyan, SD Lee, A Nguyen, X Xiao, P Tontonoz
Proceedings of the National Academy of Sciences 119 (18), e2201859119, 2022
62022
USP20 links feeding-induced cholesterol synthesis and energy expenditure
X Xiao, P Tontonoz
Science China Life Sciences 64, 337-338, 2021
32021
Lipid-and protein-directed photosensitizer proximity labeling captures the cholesterol interactome
AP Becker, E Biletch, JP Kennelly, AR Julio, M Villaneuva, RT Nagari, ...
bioRxiv, 2024
12024
A cancer cell-intrinsic GOT2-PPARδ axis suppresses antitumor immunity
H Sanford-Crane, J Abrego, C Oon, X Xiao, S Nagarajan, ...
bioRxiv, 2020.12. 25.424393, 2020
12020
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