DNA gyrase, topoisomerase IV, and the 4-quinolones K Drlica, X Zhao Microbiology and molecular biology reviews 61 (3), 377-392, 1997 | 2127 | 1997 |
Quinolone-mediated bacterial death K Drlica, M Malik, RJ Kerns, X Zhao Antimicrobial agents and chemotherapy 52 (2), 385-392, 2008 | 724 | 2008 |
Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies X Zhao, K Drlica Clinical Infectious Diseases 33 (Supplement_3), S147-S156, 2001 | 613 | 2001 |
Mutant selection window hypothesis updated K Drlica, X Zhao Clinical infectious diseases 44 (5), 681-688, 2007 | 475 | 2007 |
Quinolones: action and resistance updated K Drlica, H Hiasa, R Kerns, M Malik, A Mustaev, X Zhao Current topics in medicinal chemistry 9 (11), 981-998, 2009 | 453 | 2009 |
Mutant Prevention Concentrations of Fluoroquinolones for Clinical Isolates of Streptococcus pneumoniae JM Blondeau, X Zhao, G Hansen, K Drlica Antimicrobial Agents and Chemotherapy 45 (2), 433-438, 2001 | 418 | 2001 |
Effect of Fluoroquinolone Concentration on Selection of Resistant Mutants of Mycobacterium bovis BCG andStaphylococcus aureus Y Dong, X Zhao, J Domagala, K Drlica Antimicrobial agents and chemotherapy 43 (7), 1756-1758, 1999 | 406 | 1999 |
Reactive oxygen species and the bacterial response to lethal stress X Zhao, K Drlica Current opinion in microbiology 21, 1-6, 2014 | 397 | 2014 |
Restricting the selection of antibiotic-resistant mutant bacteria: measurement and potential use of the mutant selection window Z Xilin, K Drlica The Journal of Infectious Diseases 185 (4), 561-565, 2002 | 333 | 2002 |
Post-stress bacterial cell death mediated by reactive oxygen species Y Hong, J Zeng, X Wang, K Drlica, X Zhao Proceedings of the National Academy of Sciences 116 (20), 10064-10071, 2019 | 316 | 2019 |
DNA topoisomerase targets of the fluoroquinolones: a strategy for avoiding bacterial resistance X Zhao, C Xu, J Domagala, K Drlica Proceedings of the National Academy of Sciences 94 (25), 13991-13996, 1997 | 305 | 1997 |
Contribution of oxidative damage to antimicrobial lethality X Wang, X Zhao Antimicrobial agents and chemotherapy 53 (4), 1395-1402, 2009 | 259 | 2009 |
Selection of antibiotic-resistant bacterial mutants: allelic diversity among fluoroquinolone-resistant mutations J Zhou, Y Dong, X Zhao, S Lee, A Amin, S Ramaswamy, J Domagala, ... The Journal of infectious diseases 182 (2), 517-525, 2000 | 192 | 2000 |
Mutant Prevention Concentration as a Measure of Antibiotic Potency: Studies with Clinical Isolates ofMycobacterium tuberculosis Y Dong, X Zhao, BN Kreiswirth, K Drlica Antimicrobial agents and chemotherapy 44 (9), 2581-2584, 2000 | 180 | 2000 |
Fluoroquinolone action against mycobacteria: effects of C-8 substituents on growth, survival, and resistance Y Dong, C Xu, X Zhao, J Domagala, K Drlica Antimicrobial agents and chemotherapy 42 (11), 2978-2984, 1998 | 177 | 1998 |
Fluoroquinolone-gyrase-DNA complexes: two modes of drug binding A Mustaev, M Malik, X Zhao, N Kurepina, G Luan, LM Oppegard, H Hiasa, ... Journal of Biological Chemistry 289 (18), 12300-12312, 2014 | 167 | 2014 |
Contribution of reactive oxygen species to pathways of quinolone-mediated bacterial cell death X Wang, X Zhao, M Malik, K Drlica Journal of Antimicrobial Chemotherapy 65 (3), 520-524, 2010 | 159 | 2010 |
Emergence of resistant Streptococcus pneumoniae in an in vitro dynamic model that simulates moxifloxacin concentrations inside and outside the mutant selection … SH Zinner, IY Lubenko, D Gilbert, K Simmons, X Zhao, K Drlica, AA Firsov Journal of Antimicrobial Chemotherapy 52 (4), 616-622, 2003 | 157 | 2003 |
Lethal fragmentation of bacterial chromosomes mediated by DNA gyrase and quinolones M Malik, X Zhao, K Drlica Molecular microbiology 61 (3), 810-825, 2006 | 154 | 2006 |
Fluoroquinolone-Resistant Streptococcus pneumoniae Associated with Levofloxacin Therapy C Urban, N Rahman, X Zhao, N Mariano, S Segal-Maurer, K Drlica, ... The Journal of infectious diseases 184 (6), 794-798, 2001 | 152 | 2001 |