| Discovery of the once-weekly glucagon-like peptide-1 (GLP-1) analogue semaglutide J Lau, P Bloch, L Schäffer, I Pettersson, J Spetzler, J Kofoed, K Madsen, ... Journal of medicinal chemistry 58 (18), 7370-7380, 2015 | 822 | 2015 |
| Capsaicin‐sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type … DX Gram, B Ahrén, I Nagy, UB Olsen, CL Brand, F Sundler, R Tabanera, ... European Journal of Neuroscience 25 (1), 213-223, 2007 | 185 | 2007 |
| Plasma calcitonin gene-related peptide is increased prior to obesity, and sensory nerve desensitization by capsaicin improves oral glucose tolerance in obese Zucker rats DX Gram, AJ Hansen, M Wilken, T Elm, O Svendsen, RD Carr, B Ahrén, ... European journal of endocrinology 153 (6), 963-969, 2005 | 133 | 2005 |
| Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats RJ McCrimmon, ML Evans, X Fan, EC McNay, O Chan, Y Ding, W Zhu, ... Diabetes 54 (11), 3169-3174, 2005 | 124 | 2005 |
| Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach SG Moesgaard, B Ahrén, RD Carr, DX Gram, CL Brand, F Sundler Regulatory peptides 120 (1-3), 261-267, 2004 | 98 | 2004 |
| Study on biological variation of haemostatic parameters in clinically healthy dogs BO Wiinberg, AL Jensen, M Kjelgaard-Hansen, R Rojkjaer, PI Johansson, ... The veterinary journal 174 (1), 62-68, 2007 | 96 | 2007 |
| Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma … DX Gram, AJ Hansen, CF Deacon, CL Brand, U Ribel, M Wilken, RD Carr, ... European journal of pharmacology 509 (2-3), 211-217, 2005 | 73 | 2005 |
| 40th EASD Annual Meeting of the European Association for the Study of Diabetes: Munich, Germany, 5–9 September 2004 M Veitenhansl, K Stegner, FX Hierl, C Dieterle, H Feldmeier, B Gutt, ... Diabetologia 47, A1-A464, 2004 | 55 | 2004 |
| TRPV1: a potential therapeutic target in type 2 diabetes and comorbidities? DX Gram, JJ Holst, A Szallasi Trends in Molecular Medicine 23 (11), 1002-1013, 2017 | 46 | 2017 |
| Ablation of capsaicin-sensitive afferent nerves affects insulin response during an intravenous glucose tolerance test EHEM van de Wall, DX Gram, JH Strubbe, AJW Scheurink, JM Koolhaas Life sciences 77 (11), 1283-1292, 2005 | 35 | 2005 |
| Sensory nerve inactivation by resiniferatoxin improves insulin sensitivity in male obese Zucker rats SG Moesgaard, CL Brand, J Sturis, B Ahrén, M Wilken, J Fleckner, ... American Journal of Physiology-Endocrinology and Metabolism 288 (6), E1137-E1145, 2005 | 35 | 2005 |
| Using evolutionary information and ancestral sequences to understand the sequence–function relationship in GLP-1 agonists M Skovgaard, JT Kodra, DX Gram, SM Knudsen, D Madsen, DA Liberles Journal of molecular biology 363 (5), 977-988, 2006 | 31 | 2006 |
| Subdiaphragmatic vagal deafferentation affects body weight gain and glucose metabolism in obese male Zucker (fa/fa) rats B Ferrari, M Arnold, RD Carr, W Langhans, G Pacini, TB Bodvarsdóttir, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2005 | 30 | 2005 |
| Amplified hormonal counterregulatory responses to hypoglycemia in rats after systemic delivery of a SUR-1–selective K+ channel opener? X Fan, Y Ding, H Cheng, DX Gram, RS Sherwin, RJ McCrimmon Diabetes 57 (12), 3327-3334, 2008 | 20 | 2008 |
| Glucose intolerance in a xenotransplantation model: studies in alpha‐gal knockout mice K Dahl, K Buschard, DX Gram, AJF d'Apice, AK Hansen Apmis 114 (11), 805-811, 2006 | 20 | 2006 |
| TRPV1 antagonists as novel anti-diabetic agents: regulation of oral glucose tolerance and insulin secretion through reduction of low-grade inflammation? DX Gram, J Fribo, I Nagy, C Gotfredsen, A Charrua, JB Hansen, ... Medical Sciences 7 (8), 82, 2019 | 18 | 2019 |
| Insulin analogues with an acyl and alkylene glycol moiety P Madsen, TB Kjeldsen, T Hoeg-Jensen, TM Tagmose, P Jakobsen, ... US Patent 9,150,633, 2015 | 10 | 2015 |
| Inhibition of the activity of the capsaicin receptor in the treatment of type 1 diabetes, type 2 diabetes, impaired glucose tolerance or insulin resistance DX Gram, AJ Hansen US Patent 8,455,504, 2013 | 10 | 2013 |
| Sensory nerve desensitisation in Zucker diabetic fatty rats preserves in vitro insulin secretion DX Gram, B Ahren, F Sundler, UB Olsen, AJ Hansen, RD Carr, CL Brand Diabetologia 43, A130-A130, 2000 | 8 | 2000 |
| Capsaicin Desensitisation Delays the Progression of Type 2 Diabetes in the Zucker Diabetic Fatty Rat D GRAM, UB OLSEN, AJ HANSEN, M WILKEN, R CARR, CL BRAND Diabetes 49 (5), A428-A428, 2000 | 8 | 2000 |
