| ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair JR Klim, LA Williams, F Limone, I Guerra San Juan, BN Davis-Dusenbery, ... Nature neuroscience 22 (2), 167-179, 2019 | 450 | 2019 |
| C9orf72 suppresses systemic and neural inflammation induced by gut bacteria A Burberry, MF Wells, F Limone, A Couto, KS Smith, J Keaney, G Gillet, ... Nature 582 (7810), 89-94, 2020 | 225 | 2020 |
| Combining NGN2 programming with developmental patterning generates human excitatory neurons with NMDAR-mediated synaptic transmission R Nehme, E Zuccaro, SD Ghosh, C Li, JL Sherwood, O Pietilainen, ... Cell reports 23 (8), 2509-2523, 2018 | 218 | 2018 |
| Cell-of-origin-specific 3D genome structure acquired during somatic cell reprogramming PHL Krijger, B Di Stefano, E de Wit, F Limone, C Van Oevelen, W De Laat, ... Cell stem cell 18 (5), 597-610, 2016 | 213 | 2016 |
| C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4 B Di Stefano, S Collombet, JS Jakobsen, M Wierer, JL Sardina, A Lackner, ... Nature cell biology 18 (4), 371-381, 2016 | 119 | 2016 |
| Loss of mouse Stmn2 function causes motor neuropathy IG San Juan, LA Nash, KS Smith, MF Leyton-Jaimes, M Qian, JR Klim, ... Neuron 110 (10), 1671-1688. e6, 2022 | 48 | 2022 |
| Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro MJ Dolan, M Therrien, S Jereb, T Kamath, V Gazestani, T Atkeson, ... Nature Immunology 24 (8), 1382-1390, 2023 | 34 | 2023 |
| Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients DA Mordes, M Prudencio, LD Goodman, JR Klim, R Moccia, F Limone, ... Acta neuropathologica communications 6, 1-13, 2018 | 32 | 2018 |
| De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells A Fukuda, DZ Hazelbaker, N Motosugi, J Hao, F Limone, A Beccard, ... Stem Cell Reports 16 (9), 2138-2148, 2021 | 20 | 2021 |
| Efficient generation of lower induced Motor Neurons by coupling Ngn2 expression with developmental cues F Limone, IG San Juan, JM Mitchell, JLM Smith, K Raghunathan, D Meyer, ... Cell reports 42 (1), 2023 | 19 | 2023 |
| A resource for generating and manipulating human microglial states in vitro MJ Dolan, M Therrien, S Jereb, T Kamath, T Atkeson, SE Marsh, A Goeva, ... BioRxiv, 2022.05. 02.490100, 2022 | 14 | 2022 |
| Single-nucleus sequencing reveals enriched expression of genetic risk factors sensitises Motor Neurons to degeneration in ALS F Limone, D Mordes, A Couto, O Pietiläinen, BJ Joseph, A Burberry, ... biorxiv, 1-9, 2021 | 14 | 2021 |
| Loss of TBK1 activity leads to TDP-43 proteinopathy through lysosomal dysfunction in human motor neurons J Hao, MF Wells, G Niu, IG San Juan, F Limone, A Fukuda, ... BioRxiv, 2021.10. 11.464011, 2021 | 13 | 2021 |
| Small-molecule screen reveals pathways that regulate C4 secretion in stem cell-derived astrocytes F Rapino, T Natoli, F Limone, E O’Connor, J Blank, M Tegtmeyer, W Chen, ... Stem Cell Reports 18 (1), 237-253, 2023 | 11 | 2023 |
| Pluripotent stem cell strategies for rebuilding the human brain F Limone, JR Klim, DA Mordes Frontiers in Aging Neuroscience 14, 1017299, 2022 | 10 | 2022 |
| Considerations and practical implications of performing a phenotypic CRISPR/Cas survival screen A Ashoti, F Limone, M van Kranenburg, A Alemany, M Baak, J Vivié, ... Plos one 17 (2), e0263262, 2022 | 4 | 2022 |
| Loss of mouse Stmn2 function causes motor neuropathy (vol 110, pg 1671, 2022) IGS Juan, LA Nash, KS Smith, MF Leyton-Jaimes, M Qian, JR Klim, ... Neuron 110 (23), 4031-4031, 2022 | 3 | 2022 |
| Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS F Limone, DA Mordes, A Couto, BJ Joseph, JM Mitchell, M Therrien, ... Nature Aging, 1-14, 2024 | 2 | 2024 |
| Myeloid and lymphoid expression of C9orf72 regulates IL-17A signaling in mice F Limone, A Couto, JY Wang, Y Zhang, B McCourt, C Huang, A Minkin, ... Science Translational Medicine 16 (732), eadg7895, 2024 | 2 | 2024 |
| A genome-wide CRISPR/Cas phenotypic screen for modulators of DUX4 cytotoxicity reveals screen complications A Ashoti, F Limone, M van Kranenburg, A Alemany, M Baak, J Vivié, ... bioRxiv, 2020.07. 27.223420, 2020 | 1 | 2020 |
