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Conor McMahon
Conor McMahon
Principal Scientist, Sanofi
在 sanofi.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Yeast surface display platform for rapid discovery of conformationally selective nanobodies
C McMahon, AS Baier, R Pascolutti, M Wegrecki, S Zheng, JX Ong, ...
Nature structural & molecular biology 25 (3), 289-296, 2018
4702018
Protein design and variant prediction using autoregressive generative models
JE Shin, AJ Riesselman, AW Kollasch, C McMahon, E Simon, C Sander, ...
Nature communications 12 (1), 2403, 2021
3412021
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR
LM Wingler, MA Skiba, C McMahon, DP Staus, ALW Kleinhenz, ...
Science 367 (6480), 888-892, 2020
1982020
Distinctive activation mechanism for angiotensin receptor revealed by a synthetic nanobody
LM Wingler, C McMahon, DP Staus, RJ Lefkowitz, AC Kruse
Cell 176 (3), 479-490. e12, 2019
1832019
Structural basis for G protein–coupled receptor signaling
SC Erlandson, C McMahon, AC Kruse
Annual review of biophysics 47 (1), 1-18, 2018
1252018
Rapid generation of potent antibodies by autonomous hypermutation in yeast
A Wellner, C McMahon, MSA Gilman, JR Clements, S Clark, KM Nguyen, ...
Nature chemical biology 17 (10), 1057-1064, 2021
1032021
A powerful method combining homologous recombination and site-specific recombination for targeted mutagenesis in Drosophila
G Gao, C McMahon, J Chen, YS Rong
Proceedings of the National Academy of Sciences 105 (37), 13999-14004, 2008
802008
Sec16 influences transitional ER sites by regulating rather than organizing COPII
N Bharucha, Y Liu, E Papanikou, C McMahon, M Esaki, PD Jeffrey, ...
Molecular biology of the cell 24 (21), 3406-3419, 2013
762013
Accelerating protein design using autoregressive generative models
A Riesselman, JE Shin, A Kollasch, C McMahon, E Simon, C Sander, ...
BioRxiv, 757252, 2019
462019
Synthetic nanobodies as angiotensin receptor blockers
C McMahon, DP Staus, LM Wingler, J Wang, MA Skiba, M Elgeti, ...
Proceedings of the National Academy of Sciences 117 (33), 20284-20291, 2020
452020
The structure of Sec12 implicates potassium ion coordination in Sar1 activation
C McMahon, SM Studer, C Clendinen, GP Dann, PD Jeffrey, FM Hughson
Journal of Biological Chemistry 287 (52), 43599-43606, 2012
382012
Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design
A Amcheslavsky, AL Wallace, M Ejemel, Q Li, CT McMahon, M Stoppato, ...
Scientific reports 11 (1), 2751, 2021
312021
A nanobody targeting the LIN28: let-7 interaction fragment of TUT4 blocks uridylation of let-7
C Yu, L Wang, RG Rowe, A Han, W Ji, C McMahon, AS Baier, YC Huang, ...
Proceedings of the National Academy of Sciences 117 (9), 4653-4663, 2020
222020
Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1
SM Travis, K DAmico, IM Yu, C McMahon, S Hamid, G Ramirez-Arellano, ...
Journal of Biological Chemistry 295 (30), 10125-10135, 2020
212020
ER-associated retrograde SNAREs and the Dsl1 complex mediate an alternative, Sey1p-independent homotypic ER fusion pathway
JV Rogers, C McMahon, A Baryshnikova, FM Hughson, MD Rose
Molecular biology of the cell 25 (21), 3401-3412, 2014
202014
Accelerating protein design using autoregressive generative models. bioRxiv
AJ Riesselman, JE Shin, AW Kollasch, C McMahon, E Simon, C Sander, ...
September 10, 757252, 2019
162019
Antibodies expand the scope of angiotensin receptor pharmacology
MA Skiba, SM Sterling, S Rawson, S Zhang, H Xu, H Jiang, GR Nemeth, ...
Nature Chemical Biology, 1-9, 2024
102024
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants
Q Li, F Humphries, RC Girardin, A Wallace, M Ejemel, A Amcheslavsky, ...
Frontiers in immunology 13, 995412, 2022
102022
Platform for rapid nanobody discovery in vitro
C McMahon, AS Baier, S Zheng, R Pascolutti, JX Ong, SC Erlandson, ...
BioRxiv, 151043, 2017
62017
A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability
F Ferrara, A Fanni, AAR Teixeira, E Molina, C Leal-Lopes, A DeAguero, ...
Mabs 16 (1), 2394230, 2024
2024
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