Yeast surface display platform for rapid discovery of conformationally selective nanobodies C McMahon, AS Baier, R Pascolutti, M Wegrecki, S Zheng, JX Ong, ... Nature structural & molecular biology 25 (3), 289-296, 2018 | 470 | 2018 |
Protein design and variant prediction using autoregressive generative models JE Shin, AJ Riesselman, AW Kollasch, C McMahon, E Simon, C Sander, ... Nature communications 12 (1), 2403, 2021 | 341 | 2021 |
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR LM Wingler, MA Skiba, C McMahon, DP Staus, ALW Kleinhenz, ... Science 367 (6480), 888-892, 2020 | 198 | 2020 |
Distinctive activation mechanism for angiotensin receptor revealed by a synthetic nanobody LM Wingler, C McMahon, DP Staus, RJ Lefkowitz, AC Kruse Cell 176 (3), 479-490. e12, 2019 | 183 | 2019 |
Structural basis for G protein–coupled receptor signaling SC Erlandson, C McMahon, AC Kruse Annual review of biophysics 47 (1), 1-18, 2018 | 125 | 2018 |
Rapid generation of potent antibodies by autonomous hypermutation in yeast A Wellner, C McMahon, MSA Gilman, JR Clements, S Clark, KM Nguyen, ... Nature chemical biology 17 (10), 1057-1064, 2021 | 103 | 2021 |
A powerful method combining homologous recombination and site-specific recombination for targeted mutagenesis in Drosophila G Gao, C McMahon, J Chen, YS Rong Proceedings of the National Academy of Sciences 105 (37), 13999-14004, 2008 | 80 | 2008 |
Sec16 influences transitional ER sites by regulating rather than organizing COPII N Bharucha, Y Liu, E Papanikou, C McMahon, M Esaki, PD Jeffrey, ... Molecular biology of the cell 24 (21), 3406-3419, 2013 | 76 | 2013 |
Accelerating protein design using autoregressive generative models A Riesselman, JE Shin, A Kollasch, C McMahon, E Simon, C Sander, ... BioRxiv, 757252, 2019 | 46 | 2019 |
Synthetic nanobodies as angiotensin receptor blockers C McMahon, DP Staus, LM Wingler, J Wang, MA Skiba, M Elgeti, ... Proceedings of the National Academy of Sciences 117 (33), 20284-20291, 2020 | 45 | 2020 |
The structure of Sec12 implicates potassium ion coordination in Sar1 activation C McMahon, SM Studer, C Clendinen, GP Dann, PD Jeffrey, FM Hughson Journal of Biological Chemistry 287 (52), 43599-43606, 2012 | 38 | 2012 |
Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design A Amcheslavsky, AL Wallace, M Ejemel, Q Li, CT McMahon, M Stoppato, ... Scientific reports 11 (1), 2751, 2021 | 31 | 2021 |
A nanobody targeting the LIN28: let-7 interaction fragment of TUT4 blocks uridylation of let-7 C Yu, L Wang, RG Rowe, A Han, W Ji, C McMahon, AS Baier, YC Huang, ... Proceedings of the National Academy of Sciences 117 (9), 4653-4663, 2020 | 22 | 2020 |
Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1 SM Travis, K DAmico, IM Yu, C McMahon, S Hamid, G Ramirez-Arellano, ... Journal of Biological Chemistry 295 (30), 10125-10135, 2020 | 21 | 2020 |
ER-associated retrograde SNAREs and the Dsl1 complex mediate an alternative, Sey1p-independent homotypic ER fusion pathway JV Rogers, C McMahon, A Baryshnikova, FM Hughson, MD Rose Molecular biology of the cell 25 (21), 3401-3412, 2014 | 20 | 2014 |
Accelerating protein design using autoregressive generative models. bioRxiv AJ Riesselman, JE Shin, AW Kollasch, C McMahon, E Simon, C Sander, ... September 10, 757252, 2019 | 16 | 2019 |
Antibodies expand the scope of angiotensin receptor pharmacology MA Skiba, SM Sterling, S Rawson, S Zhang, H Xu, H Jiang, GR Nemeth, ... Nature Chemical Biology, 1-9, 2024 | 10 | 2024 |
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants Q Li, F Humphries, RC Girardin, A Wallace, M Ejemel, A Amcheslavsky, ... Frontiers in immunology 13, 995412, 2022 | 10 | 2022 |
Platform for rapid nanobody discovery in vitro C McMahon, AS Baier, S Zheng, R Pascolutti, JX Ong, SC Erlandson, ... BioRxiv, 151043, 2017 | 6 | 2017 |
A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability F Ferrara, A Fanni, AAR Teixeira, E Molina, C Leal-Lopes, A DeAguero, ... Mabs 16 (1), 2394230, 2024 | | 2024 |