| Synthesis, Anticancer Activities and Molecular Docking Studies of a Novel Class of 2-Phenyl-5,6,7,8-tetrahydroimidazo [1,2-b]pyridazine Derivatives Bearing … O Bourzikat, A El Abbouchi, H Ghammaz, N El Brahmi, E El Fahime, ... Molecules 27 (16), 5238, 2022 | 15 | 2022 |
| Synthesis and biological evaluation of ethacrynic acid derivatives bearing sulfonamides as potent anti-cancer agents A El Abbouchi, N El Brahmi, MA Hiebel, J Bignon, G Guillaumet, ... Bioorganic & Medicinal Chemistry Letters 30 (19), 127426, 2020 | 14 | 2020 |
| “On Water” Palladium Catalyzed Direct Arylation of 1H-Indazole and 1H-7-Azaindazole K Gambouz, A El Abbouchi, S Nassiri, F Suzenet, M Bousmina, M Akssira, ... Molecules 25 (12), 2820, 2020 | 14 | 2020 |
| Synthesis and evaluation of a novel class of ethacrynic acid derivatives containing triazoles as potent anticancer agents A El Abbouchi, N El Brahmi, MA Hiebel, J Bignon, G Guillaumet, ... Bioorganic Chemistry 115, 105293, 2021 | 13 | 2021 |
| Improvement of the chemical reactivity of michael acceptor of ethacrynic acid correlates with antiproliferative activities A El Abbouchi, N El Brahmi, MA Hiebel, H Ghammaz, E El Fahime, ... Molecules 28 (2), 910, 2023 | 9 | 2023 |
| Palladium‐Catalyzed Oxidative Arylation of 1H‐Indazoles with Arenes K Gambouz, AE Abbouchi, S Nassiri, F Suzenet, M Bousmina, M Akssira, ... European Journal of Organic Chemistry 2020 (48), 7435-7439, 2020 | 7 | 2020 |
| An overview on the synthesis and anticancer properties of ethacrynic acid and their analogues N El Brahmi, A El Abbouchi, S El Kazzouli Results in Chemistry, 101117, 2023 | 5 | 2023 |
| Direct arylation and Suzuki-Miyaura coupling of imidazo [1, 2-a] pyridines catalyzed by (SIPr) Pd (allyl) Cl complex under microwave-irradiation A El Abbouchi, J Koubachi, N El Brahmi, S El Kazzouli Mediterranean Journal of Chemistry 9 (5), 347-354, 2019 | 5 | 2019 |
| In vitro cytotoxic, antioxidant, hemolytic and cytoprotective potential of promising ethacrynic acid derivatives A Idir, N Bouchmaa, A El Abbouchi, N El Brahmi, RB Mrid, Y Bouargalne, ... Moroccan Journal of Chemistry 11 (3), J. Chem. 11 N° 3 (2023) 657-673, 2023 | 3 | 2023 |
| Anticancer activities of a novel family of ethacrynic acid derivatives S El Kazzouli, Z Abdelmadjid, N El Brahmi, A El Abbouchi, K Boujdi, ... US Patent App. 17/297,252, 2022 | 2 | 2022 |
| Design, Synthesis, Computational Studies, and Anti-Proliferative Evaluation of Novel Ethacrynic Acid Derivatives Containing Nitrogen Heterocycle, Urea, and Thiourea Moieties as … A El Abbouchi, K Mkhayar, S Elkhattabi, N El Brahmi, MA Hiebel, J Bignon, ... Molecules 29 (7), 1437, 2024 | 1 | 2024 |
| Ligand-based design of novel quinoline derivatives as potential anticancer agents: An in-silico virtual screening approach K Mkhayar, O Daoui, R Haloui, K Elkhattabi, A Elabbouchi, S Chtita, ... Molecules 29 (2), 426, 2024 | 1 | 2024 |
| Design of new small molecules derived from indolin-2-one as potent TRKs inhibitors using a computer-aided drug design approach R Haloui, K Mkhayar, O Daoui, K El Khattabi, A El Abbouchi, S Chtita, ... Journal of Biomolecular Structure and Dynamics, 1-18, 2024 | 1 | 2024 |
| Design, synthesis, in-vitro, in-silico, DFT and POM studies of a novel family of sulfonamides as potent anti-triple-negative breast cancer agents N Saghdani, A El Abbouchi, N El Brahmi, A Idir, KO Rachedi, ... Computational Biology and Chemistry, 108214, 2024 | | 2024 |
| Ethacrynic acid derivatives as inhibitors of mpro protease and sars-cov-2 replication S El Kazzouli, N Touil, E El Fahime, A El Abbouchi, M Hemlali, ... US Patent App. 18/560,280, 2024 | | 2024 |
| Development of a new experimental NMR strategy for covalent cysteine protease inhibitors screening: toward enhanced drug discovery A Chihab, N El Brahmi, G Hamdoun, A El Abbouchi, H Ghammaz, N Touil, ... RSC advances 14 (37), 26829-26836, 2024 | | 2024 |
| Synthèse et évaluation in vitro de nouveaux dérivés de l’acide éthacrynique comme agents anticancéreux A El Abbouchi Orléans, 2020 | | 2020 |
| Discovery of new small molecules inhibitors for EphB4 receptor tyrosine kinase with a fragment-based drug design approach A Ballari, R Haloui, O Daouı, K Mkhayar, KK Allah, S Chtita, A El Abbouchi, ... Turkish Computational and Theoretical Chemistry 9 (1), 75-89, 0 | | |
| Synthesis, Characterization, Admet Prediction, and Molecular Docking Studies of Novel Indole Derivatives as Potent Sars-Cov-2 Inhibitors Targeting Mpro and Plpro Enzymes S El Kazzouli, A Chihab, N El Brahmi, A El Abbouchi, A El Alaoui, ... Available at SSRN 4890066, 0 | | |
| Synthèse de nouveaux fluorophores à base d’imidazo [1, 2-b] pyridazine via la nouvelle méthode d’arylation oxydative PS EL KAZZOULI, PA MELIANI, A EL ABBOUCHI, PN EL BRAHMI, ... | | |
