p53 is required for radiation-induced apoptosis in mouse thymocytes SW Lowe, EM Schmitt, SW Smith, BA Osborne, T Jacks Nature 362 (6423), 847-849, 1993 | 3867 | 1993 |
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells S Weijzen, P Rizzo, M Braid, R Vaishnav, SM Jonkheer, A Zlobin, ... Nature medicine 8 (9), 979-986, 2002 | 761 | 2002 |
Do all programmed cell deaths occur via apoptosis? LM Schwartz, SW Smith, ME Jones, BA Osborne Proceedings of the National Academy of Sciences 90 (3), 980-984, 1993 | 745 | 1993 |
Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate–early gene nur77 ZG Liu, SW Smith, KA McLaughlin, LM Schwartz, BA Osborne Nature 367 (6460), 281-284, 1994 | 695 | 1994 |
Programmed cell death, apoptosis and killer genes. LM Schwartz, BA Osborne Immunology today 14 (12), 582-590, 1993 | 567 | 1993 |
Targeting Notch to target cancer stem cells A Pannuti, K Foreman, P Rizzo, C Osipo, T Golde, B Osborne, L Miele Clinical cancer research 16 (12), 3141-3152, 2010 | 533 | 2010 |
Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents BJ Nickoloff, BA Osborne, L Miele Oncogene 22 (42), 6598-6608, 2003 | 471 | 2003 |
Proteasomes play an essential role in thymocyte apoptosis. LM Grimm, AL Goldberg, GG Poirier, LM Schwartz, BA Osborne The EMBO Journal 15 (15), 3835-3844, 1996 | 413 | 1996 |
Cloned transchromosomic calves producing human immunoglobulin Y Kuroiwa, P Kasinathan, YJ Choi, R Naeem, K Tomizuka, EJ Sullivan, ... Nature biotechnology 20 (9), 889-894, 2002 | 411 | 2002 |
Arbiter of differentiation and death: Notch signaling meets apoptosis L Miele, B Osborne Journal of cellular physiology 181 (3), 393-409, 1999 | 378 | 1999 |
Notch1 augments NF‐κB activity by facilitating its nuclear retention HM Shin, LM Minter, OH Cho, S Gottipati, AH Fauq, TE Golde, ... The EMBO journal 25 (1), 129-138, 2006 | 371 | 2006 |
Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21 LM Minter, DM Turley, P Das, HM Shin, I Joshi, RG Lawlor, OH Cho, ... Nature immunology 6 (7), 680-688, 2005 | 362 | 2005 |
γ-Secretase inhibitors and modulators TE Golde, EH Koo, KM Felsenstein, BA Osborne, L Miele Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (12), 2898-2907, 2013 | 337 | 2013 |
Negative selection of CD4+ CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28. JA Punt, BA Osborne, Y Takahama, SO Sharrow, A Singer The Journal of experimental medicine 179 (2), 709-713, 1994 | 330 | 1994 |
Notch signalling during peripheral T-cell activation and differentiation BA Osborne, LM Minter Nature Reviews Immunology 7 (1), 64-75, 2007 | 326 | 2007 |
TCR-mediated Notch signaling regulates proliferation and IFN-γ production in peripheral T cells T Palaga, L Miele, TE Golde, BA Osborne The Journal of Immunology 171 (6), 3019-3024, 2003 | 323 | 2003 |
Notch signaling in cancer L Miele, T Golde, B Osborne Current molecular medicine 6 (8), 905-918, 2006 | 309 | 2006 |
Cutting edge: protective effects of notch-1 on TCR-induced apoptosis BM Jehn, W Bielke, WS Pear, BA Osborne The Journal of Immunology 162 (2), 635-638, 1999 | 304 | 1999 |
Notch-1 regulates NF-κB activity in hemopoietic progenitor cells P Cheng, A Zlobin, V Volgina, S Gottipati, B Osborne, EJ Simel, L Miele, ... The Journal of Immunology 167 (8), 4458-4467, 2001 | 292 | 2001 |
Notch signaling is activated by TLR stimulation and regulates macrophage functions T Palaga, C Buranaruk, S Rengpipat, AH Fauq, TE Golde, SHE Kaufmann, ... European journal of immunology 38 (1), 174-183, 2008 | 285 | 2008 |