| Characterization of cytochrome P450 enzymes and their applications in synthetic biology LN Jeffreys, HM Girvan, KJ McLean, AW Munro Methods in Enzymology 608, 189-261, 2018 | 29 | 2018 |
| Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs LN Jeffreys, H Poddar, M Golovanova, CW Levy, HM Girvan, KJ McLean, ... Scientific Reports 9 (1), 1577, 2019 | 26 | 2019 |
| A promiscuous bacterial P450: The unparalleled diversity of BM3 in pharmaceutical metabolism S Thistlethwaite, LN Jeffreys, HM Girvan, KJ McLean, AW Munro International Journal of Molecular Sciences 22 (21), 11380, 2021 | 21 | 2021 |
| Remdesivir–ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2 LN Jeffreys, SH Pennington, J Duggan, CH Caygill, RC Lopeman, ... International Journal of Antimicrobial Agents 59 (3), 106542, 2022 | 15 | 2022 |
| Comparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach L González-Paz, ML Hurtado-León, C Lossada, FV Fernández-Materán, ... Biophysical chemistry 278, 106677, 2021 | 14 | 2021 |
| Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches LN Jeffreys, KJ Pacholarz, LO Johannissen, HM Girvan, PE Barran, ... Journal of Biological Chemistry 295 (22), 7595-7607, 2020 | 14 | 2020 |
| Identification of 2-aryl-quinolone inhibitors of cytochrome bd and chemical validation of combination strategies for respiratory inhibitors against Mycobacterium tuberculosis LN Jeffreys, A Ardrey, TA Hafiz, LA Dyer, AJ Warman, N Mosallam, ... ACS Infectious Diseases 9 (2), 221-238, 2023 | 12 | 2023 |
| Structural deformability induced in proteins of potential interest associated with COVID-19 by binding of homologues present in ivermectin: Comparative study based in elastic … L Gonzalez-Paz, ML Hurtado-León, C Lossada, FV Fernández-Materán, ... Journal of Molecular Liquids 340, 117284, 2021 | 10 | 2021 |
| Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors L González-Paz, MJ Alvarado, ML Hurtado-León, C Lossada, ... Computers in biology and medicine 142, 105245, 2022 | 4 | 2022 |
| Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: A need for better understanding of inter-lab differences in preclinical assays H Box, SH Pennington, E Kijak, L Tatham, CH Caygill, RC Lopeman, ... bioRxiv, 2022 | 3 | 2022 |
| Redox driven B12-ligand switch drives CarH photoresponse H Poddar, R Rios-Santacruz, DJ Heyes, M Shanmugam, A Brookfield, ... Nature Communications 14 (1), 5082, 2023 | 2 | 2023 |
| Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters HJ Box, J Sharp, SH Pennington, E Kijak, L Tatham, CH Caygill, ... Journal of Antimicrobial Chemotherapy 79 (1), 172-178, 2024 | 1 | 2024 |
| Thermodynamics and conformational dynamics of primer nucleotide sequences associated with Monkeypox Virus (MpxV): Comparative analysis of stability and specificity with a … L González-Paz, C Lossada, ML Hurtado-León, J Vera-Villalobos, JL Paz, ... Biointerface Res Appl Chem 13 (5), 435, 2023 | 1 | 2023 |
| Interaction of the new inhibitor paxlovid (PF-07321332) and ivermectin with the monomer of the main protease SARS-CoV-2: A volumetric study based on molecular dynamics, elastic … YJ Alvarado, Y Olivarez, C Lossada, J Vera-Villalobos, JL Paz, E Vera, ... Computational Biology and Chemistry 99, 107692, 2022 | 1 | 2022 |
| Photocobilins integrate B12 and bilin photochemistry for enzyme control S Zhang, LN Jeffreys, H Poddar, Y Yu, C Liu, K Patel, LO Johannissen, ... Nature Communications 15 (1), 2740, 2024 | | 2024 |
| Photocobilins integrate B12 and bilin photochemistry for enzyme control N Scrutton, S Zhang, H Poddar, Y Yu, C Liu, K Patel, L Jeffreys, L Zhu, ... | | 2023 |
| An in vitro SARS-CoV-2 cytopathic activity screen of the'MMV COVID box' S Pennington, C Caygill, R Lopeman, L Jeffreys, J Duggan, A Breen, ... BRITISH JOURNAL OF PHARMACOLOGY 180 (4), 546-546, 2023 | | 2023 |
| Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2 L Jeffreys, SH Pennington, J Duggan, A Breen, J Jinks, A Ardrey, ... BioRxiv, 2020.12. 23.424232, 2020 | | 2020 |
| Biotechnological applications of cytochrome P450 enzymes A Munro, K McLean, J Belcher, S Matthews, H Girvan, K Tee, H Poddar, ... FEBS OPEN BIO 8, 21-21, 2018 | | 2018 |
| High-value Oxy-pharmaceuticals from P450 BM3 ‘Gatekeeper’Mutations LN Jeffreys PQDT-Global, 2018 | | 2018 |
