Human primary liver cancer–derived organoid cultures for disease modeling and drug screening L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarró, ... Nature medicine 23 (12), 1424, 2017 | 1191 | 2017 |
Small-molecule–induced DNA damage identifies alternative DNA structures in human genes R Rodriguez, KM Miller, JV Forment, CR Bradshaw, M Nikan, S Britton, ... Nature chemical biology 8 (3), 301, 2012 | 712 | 2012 |
A unique gene regulatory network resets the human germline epigenome for development WWC Tang, S Dietmann, N Irie, HG Leitch, VI Floros, CR Bradshaw, ... Cell 161 (6), 1453-1467, 2015 | 688 | 2015 |
Systems survey of endocytosis by multiparametric image analysis C Collinet, M Stöter, CR Bradshaw, N Samusik, JC Rink, D Kenski, ... Nature 464 (7286), 243, 2010 | 482 | 2010 |
Replication stress induces 53BP1-containing OPT domains in G1 cells JA Harrigan, R Belotserkovskaya, J Coates, DS Dimitrova, SE Polo, ... The Journal of cell biology 193 (1), 97-108, 2011 | 347 | 2011 |
Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications MJ Koziol, CR Bradshaw, GE Allen, ASH Costa, C Frezza, JB Gurdon Nature Structural and Molecular Biology 23 (1), 24, 2016 | 242 | 2016 |
Titration of four replication factors is essential for the Xenopus laevis midblastula transition C Collart, GE Allen, CR Bradshaw, JC Smith, P Zegerman Science 341 (6148), 893-896, 2013 | 235 | 2013 |
Mechanical cell competition kills cells via induction of lethal p53 levels L Wagstaff, M Goschorska, K Kozyrska, G Duclos, I Kucinski, A Chessel, ... Nature communications 7, 11373, 2016 | 195 | 2016 |
Sperm is epigenetically programmed to regulate gene transcription in embryos M Teperek, A Simeone, V Gaggioli, K Miyamoto, GE Allen, S Erkek, ... Genome research 26 (8), 1034-1046, 2016 | 129 | 2016 |
H3K4 methylation-dependent memory of somatic cell identity inhibits reprogramming and development of nuclear transfer embryos E Hörmanseder, A Simeone, GE Allen, CR Bradshaw, M Figlmüller, ... Cell stem cell 21 (1), 135-143. e6, 2017 | 119 | 2017 |
Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity JF Winter, S Höpfner, K Korn, BO Farnung, CR Bradshaw, G Marsico, ... Nature Cell Biology 14 (7), 666, 2012 | 113 | 2012 |
Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal development K Miyamoto, M Teperek, K Yusa, GE Allen, CR Bradshaw, JB Gurdon Science 341 (6149), 1002-1005, 2013 | 99 | 2013 |
Conformational adaptability of Redβ during DNA annealing and implications for its structural relationship with Rad52 A Erler, S Wegmann, C Elie-Caille, CR Bradshaw, M Maresca, R Seidel, ... Journal of molecular biology 391 (3), 586-598, 2009 | 81 | 2009 |
Gene resistance to transcriptional reprogramming following nuclear transfer is directly mediated by multiple chromatin-repressive pathways J Jullien, M Vodnala, V Pasque, M Oikawa, K Miyamoto, G Allen, ... Molecular cell 65 (5), 873-884. e8, 2017 | 51 | 2017 |
Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming J Jullien, K Miyamoto, V Pasque, GE Allen, CR Bradshaw, NJ Garrett, ... Molecular cell 55 (4), 524-536, 2014 | 49 | 2014 |
Reprogramming towards totipotency is greatly facilitated by synergistic effects of small molecules K Miyamoto, Y Tajima, K Yoshida, M Oikawa, R Azuma, GE Allen, ... Biology open 6 (4), 415-424, 2017 | 37 | 2017 |
Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development JE Cannon, ES Place, AMJ Eve, CR Bradshaw, A Sesay, NW Morrell, ... Mechanisms of development 130 (2-3), 122-131, 2013 | 35 | 2013 |
CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans V Gaggioli, E Zeiser, D Rivers, CR Bradshaw, J Ahringer, P Zegerman J Cell Biol 204 (4), 507-522, 2014 | 33 | 2014 |
Identification of Methylated Deoxyadenosines in Genomic DNA by dA6m DNA Immunoprecipitation MJ Koziol, CR Bradshaw, GE Allen, ASH Costa, C Frezza Bio-protocol 6 (21), 2016 | 15 | 2016 |
ProFAT: a web-based tool for the functional annotation of protein sequences CR Bradshaw, V Surendranath, B Habermann BMC bioinformatics 7 (1), 466, 2006 | 10 | 2006 |