Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism KG Kumar, JL Trevaskis, DD Lam, GM Sutton, RA Koza, VN Chouljenko, ... Cell metabolism 8 (6), 468-481, 2008 | 636 | 2008 |
Brain serotonin system in the coordination of food intake and body weight DD Lam, AS Garfield, OJ Marston, J Shaw, LK Heisler Pharmacology Biochemistry and Behavior 97 (1), 84-91, 2010 | 350 | 2010 |
Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors DD Lam, MJ Przydzial, SH Ridley, GSH Yeo, JJ Rochford, S O’Rahilly, ... Endocrinology 149 (3), 1323-1328, 2008 | 330 | 2008 |
Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways L Zhou, GM Sutton, JJ Rochford, RK Semple, DD Lam, LJ Oksanen, ... Cell metabolism 6 (5), 398-405, 2007 | 273 | 2007 |
Serotonin and energy balance: molecular mechanisms and implications for type 2 diabetes DD Lam, LK Heisler Expert reviews in molecular medicine 9 (5), 1-24, 2007 | 205 | 2007 |
Role of central melanocortin pathways in energy homeostasis AS Garfield, DD Lam, OJ Marston, MJ Przydzial, LK Heisler Trends in Endocrinology & Metabolism 20 (5), 203-215, 2009 | 164 | 2009 |
An appetite for life: brain regulation of hunger and satiety LK Heisler, DD Lam Current opinion in pharmacology 37, 100-106, 2017 | 135 | 2017 |
Partially Redundant Enhancers Cooperatively Maintain Mammalian Pomc Expression Above a Critical Functional Threshold DD Lam, FSJ de Souza, S Nasif, M Yamashita, R López-Leal, ... PLoS genetics 11 (2), e1004935, 2015 | 111 | 2015 |
Recessive mutations in the α3 (VI) collagen gene COL6A3 cause early-onset isolated dystonia M Zech, DD Lam, L Francescatto, B Schormair, AV Salminen, A Jochim, ... The American Journal of Human Genetics 96 (6), 883-893, 2015 | 101 | 2015 |
Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons LK Burke, B Doslikova, G d'Agostino, M Greenwald-Yarnell, T Georgescu, ... Molecular metabolism 5 (3), 245-252, 2016 | 92 | 2016 |
Brain glucose sensors play a significant role in the regulation of pancreatic glucose-stimulated insulin secretion MA Osundiji, DD Lam, J Shaw, CY Yueh, SP Markkula, P Hurst, C Colliva, ... Diabetes 61 (2), 321-328, 2012 | 79 | 2012 |
Leptin does not directly affect CNS serotonin neurons to influence appetite DD Lam, GM Leinninger, GW Louis, AS Garfield, OJ Marston, RL Leshan, ... Cell metabolism 13 (5), 584-591, 2011 | 75 | 2011 |
Distribution and neurochemical characterization of neurons within the nucleus of the solitary tract responsive to serotonin agonist-induced hypophagia DD Lam, L Zhou, A Vegge, PY Xiu, BT Christensen, MA Osundiji, C Yueh, ... Behavioural brain research 196 (1), 139-143, 2009 | 72 | 2009 |
Hypothalamic POMC deficiency improves glucose tolerance despite insulin resistance by increasing glycosuria KH Chhabra, JM Adams, B Fagel, DD Lam, N Qi, M Rubinstein, MJ Low Diabetes 65 (3), 660-672, 2016 | 50 | 2016 |
Update on KMT2B-Related Dystonia M Zech, DD Lam, J Winkelmann Current neurology and neuroscience reports 19, 1-11, 2019 | 48 | 2019 |
Conditional Expression of Pomc in the Lepr-Positive Subpopulation of POMC Neurons Is Sufficient for Normal Energy Homeostasis and Metabolism DD Lam, CA Attard, AJ Mercer, MG Myers, M Rubinstein, MJ Low Endocrinology 156 (4), 1292-1302, 2015 | 38 | 2015 |
Glucokinase inhibitor glucosamine stimulates feeding and activates hypothalamic neuropeptide Y and orexin neurons L Zhou, CY Yueh, DD Lam, J Shaw, M Osundiji, AS Garfield, M Evans, ... Behavioural brain research 222 (1), 274-278, 2011 | 32 | 2011 |
Role of MEIS1 in restless legs syndrome: from GWAS to functional studies in mice AV Salminen, DD Lam, J Winkelmann Advances in Pharmacology 84, 175-184, 2019 | 29 | 2019 |
Recessive variants in ZNF142 cause a complex neurodevelopmental disorder with intellectual disability, speech impairment, seizures, and dystonia K Khan, M Zech, AT Morgan, DJ Amor, M Skorvanek, TN Khan, ... Genetics in Medicine 21 (11), 2532-2542, 2019 | 23 | 2019 |
A unique de novo gain-of-function variant in CAMK4 associated with intellectual disability and hyperkinetic movement disorder M Zech, DD Lam, S Weber, R Berutti, K Poláková, P Havránková, ... Molecular Case Studies 4 (6), a003293, 2018 | 18 | 2018 |