Strategies for developing κ opioid receptor agonists for the treatment of pain with fewer side effects KF Paton, DV Atigari, S Kaska, T Prisinzano, BM Kivell Journal of Pharmacology and Experimental Therapeutics 375 (2), 332-348, 2020 | 48 | 2020 |
The analgesic and anti‐inflammatory effects of Salvinorin A analogue β‐tetrahydropyran Salvinorin B in mice KF Paton, N Kumar, RS Crowley, JL Harper, TE Prisinzano, BM Kivell European Journal of Pain 21 (6), 1039-1050, 2017 | 46 | 2017 |
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability RS Crowley, AP Riley, AM Sherwood, CE Groer, N Shivaperumal, ... Journal of medicinal chemistry 59 (24), 11027-11038, 2016 | 43 | 2016 |
Kappa opioid receptor agonist mesyl Sal B attenuates behavioral sensitization to cocaine with fewer aversive side-effects than salvinorin A in rodents BM Kivell, KF Paton, N Kumar, AS Morani, A Culverhouse, A Shepherd, ... Molecules 23 (10), 2602, 2018 | 36 | 2018 |
Addressing structural flexibility at the A-ring on salvinorin A: discovery of a potent kappa-opioid agonist with enhanced metabolic stability AM Sherwood, RS Crowley, KF Paton, A Biggerstaff, B Neuenswander, ... Journal of medicinal chemistry 60 (9), 3866-3878, 2017 | 31 | 2017 |
Evaluation of biased and balanced salvinorin A analogs in preclinical models of pain KF Paton, A Biggerstaff, S Kaska, RS Crowley, AC La Flamme, ... Frontiers in Neuroscience 14, 765, 2020 | 23 | 2020 |
The mixed kappa and delta opioid receptor agonist, MP1104, attenuates chemotherapy-induced neuropathic pain DV Atigari, KF Paton, R Uprety, A Váradi, AF Alder, B Scouller, JH Miller, ... Neuropharmacology 185, 108445, 2021 | 15 | 2021 |
N-Docosahexaenoyl ethanolamine (Synaptamide) has antinociceptive effects in male mice KF Paton, R Shirazi, M Vyssotski, BM Kivell European journal of pain (London, England), 2020 | 15 | 2020 |
The Salvinorin analogue, ethoxymethyl ether Salvinorin B, promotes remyelination in preclinical models of multiple sclerosis KF Paton, K Robichon, N Templeton, L Denny, A Al Abadey, D Luo, ... Frontiers in Neurology, 2410, 2021 | 12 | 2021 |
Sex differences in the behavioural aspects of the cuprizone-induced demyelination model in mice KF Paton, S Hong, A Biggerstaff, BM Kivell Brain Sciences 12 (12), 1687, 2022 | 8 | 2022 |
Sex differences in kappa opioid receptor agonist mediated attenuation of chemotherapy-induced neuropathic pain in mice KF Paton, D Luo, AC La Flamme, TE Prisinzano, BM Kivell Frontiers in Pharmacology 13, 813562, 2022 | 6 | 2022 |
KAPPA OPIOID RECEPTOR AGONISTS MODULATE THE ANTI-INFLAMMATORY ACTIONS OF MICROGLIA AND PROMOTE OLIGODENDROCYTE MATURATION AND MYELIN REPAIR IN PRECLINICAL MODELS OF MULTIPLE … B Kivell, R Bibi, B Pengelly, R Van De Wetering, K Paton, D Luo, ... IBRO Neuroscience Reports 15, S592, 2023 | 1 | 2023 |
Investigating the antinociceptive effects of N-docosahexaenoyl ethanolamine and novel kappa opioid receptor agonists K Paton Open Access Te Herenga Waka-Victoria University of Wellington, 2018 | 1 | 2018 |
Kappa opioid receptor agonists promote oligodendrocyte maturation, remyelination and functional recovery in preclinical mouse models R Bibi, K Paton, AN Biggerstaff, L Denny, D Luo, K Robichon, ... Open Access Te Herenga Waka-Victoria University of Wellington, 2022 | | 2022 |
Therapeutic administration of the Salvinorin A analogue, EOM, enabled functional recovery and remyelination in two experimental models of multiple sclerosis B Kivell, N Templeton, A Al Abadey, K Paton, T Prisinzano, A La Flamme MULTIPLE SCLEROSIS JOURNAL 25, 908-909, 2019 | | 2019 |