Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner OR Mahon, DC Browe, T Gonzalez-Fernandez, P Pitacco, IT Whelan, ... Biomaterials 239, 119833, 2020 | 260 | 2020 |
Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues GM Cunniffe, PJ Díaz-Payno, EJ Sheehy, SE Critchley, HV Almeida, ... Biomaterials 188, 63-73, 2019 | 110 | 2019 |
Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages LC Shanley, OR Mahon, DJ Kelly, A Dunne Acta Biomaterialia 133, 208-221, 2021 | 65 | 2021 |
Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization OR Mahon, DJ Kelly, GM McCarthy, A Dunne Osteoarthritis and Cartilage 28 (5), 603-612, 2020 | 63 | 2020 |
Growth plate extracellular matrix-derived scaffolds for large bone defect healing. GM Cunniffe, PJ Díaz-Payno, JS Ramey, OR Mahon, A Dunne, ... Royal College of Surgeons in Ireland, 2017 | 49 | 2017 |
Orthopaedic implant materials drive M1 macrophage polarization in a spleen tyrosine kinase-and mitogen-activated protein kinase-dependent manner OR Mahon, S O'Hanlon, CC Cunningham, GM McCarthy, C Hobbs, ... Acta biomaterialia 65, 426-435, 2018 | 43 | 2018 |
Glyoxal cross‐linking of solubilized extracellular matrix to produce highly porous, elastic, and chondro‐permissive scaffolds for orthopedic tissue engineering DC Browe, OR Mahon, PJ Díaz‐Payno, N Cassidy, I Dudurych, A Dunne, ... Journal of Biomedical Materials Research Part A 107 (10), 2222-2234, 2019 | 35 | 2019 |
Disease-associated particulates and joint inflammation; mechanistic insights and potential therapeutic targets OR Mahon, A Dunne Frontiers in Immunology 9, 1145, 2018 | 23 | 2018 |
A spheroid model of early and late‐stage osteosarcoma mimicking the divergent relationship between tumor elimination and bone regeneration FE Freeman, R Burdis, OR Mahon, DJ Kelly, N Artzi Advanced Healthcare Materials 11 (7), 2101296, 2022 | 13 | 2022 |
Extracellular matrix scaffolds derived from different musculoskeletal tissues drive distinct macrophage phenotypes and direct tissue-specific cellular differentiation OR Mahon, DC Browe, PJ Diaz-Payno, P Pitacco, KT Cunningham, ... Journal of Immunology and Regenerative Medicine 12, 100041, 2021 | 13 | 2021 |
S100A8 acts as an autocrine priming signal for heme-induced human Mϕ pro-inflammatory responses in hemolytic inflammation AAA Silveira, OR Mahon, CC Cunningham, EM Corr, R Mendonça, ... Journal of leukocyte biology 106 (1), 35-43, 2019 | 12 | 2019 |
Localized nanoparticle‐mediated delivery of miR‐29b normalizes the dysregulation of bone homeostasis caused by osteosarcoma whilst simultaneously inhibiting tumor growth FE Freeman, P Dosta, LC Shanley, N Ramirez Tamez, CJ Riojas Javelly, ... Advanced Materials 35 (23), 2207877, 2023 | 9 | 2023 |
Extracellular vesicle functionalized melt electrowritten scaffolds for bone tissue engineering KF Eichholz, A Federici, M Riffault, I Woods, OR Mahon, L O’Driscoll, ... Advanced NanoBiomed Research 1 (10), 2100037, 2021 | 9 | 2021 |
Macrophage metabolic profile is altered by hydroxyapatite particle size LC Shanley, OR Mahon, SA O'Rourke, NGB Neto, MG Monaghan, ... Acta Biomaterialia 160, 311-321, 2023 | 8 | 2023 |
Generating an M2 pro‐regenerative macrophage phenotype using nanoHA particles for bone tissue engineering O Mahon European Cells and Materials 33, 2017 | 1 | 2017 |
Characterisation of Chronic Lymphocytic Leukaemia (CLL) immune profiles using single cell multi-omics OR Mahon, C King, E Fennell, SE Hickey, PA Kiely, R Clifford, K McGourty EUROPEAN JOURNAL OF IMMUNOLOGY 52, 70-70, 2022 | | 2022 |
EXTRACELLULAR MATRIX SCAFFOLDS DERIVED FROM DIFFERENT MUSCULOSKELETAL TISSUES DRIVE DISTINCT MACROPHAGE PHENOTYPES AND DIRECT TISSUE-SPECIFIC CELLULAR DIFFERENTIATION OR Mahon, DC Browe, P Pitacco, P Diaz-Payno, A Dunne, DJ Kelly TISSUE ENGINEERING PART A 28, S540-S540, 2022 | | 2022 |
Mechanically Activated Extracellular Vesicle Functionalised Melt Electrowritten Materials for Bone Regeneration: A Mechano-Biomimetic Scaffold KF Eichholz, A Federici, M Riffault, I Woods, OR Mahon, L O’Driscoll, ... bioRxiv, 2021.03. 29.437528, 2021 | | 2021 |
Characterisation of the immune response to calcium phosphate particulates; implications for osteoarthritis and bone tissue engineering O Mahon Trinity College Dublin, 2020 | | 2020 |