Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes MD Szczelkun, MS Tikhomirova, T Sinkunas, G Gasiunas, T Karvelis, ... Proceedings of the National Academy of Sciences 111 (27), 9798-9803, 2014 | 521 | 2014 |
One‐and three‐dimensional pathways for proteins to reach specific DNA sites NP Stanford, MD Szczelkun, JF Marko, SE Halford The EMBO journal, 2000 | 227 | 2000 |
Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme I Whitehouse, C Stockdale, A Flaus, MD Szczelkun, T Owen-Hughes Molecular and cellular biology 23 (6), 1935-1945, 2003 | 193 | 2003 |
Measuring motion on DNA by the type I restriction endonuclease EcoR124I using triplex displacement K Firman, MD Szczelkun The EMBO journal, 2000 | 141 | 2000 |
Enzyme-mediated DNA looping SE Halford, AJ Welsh, MD Szczelkun Annu. Rev. Biophys. Biomol. Struct. 33 (1), 1-24, 2004 | 118 | 2004 |
Subunit assembly and mode of DNA cleavage of the type III restriction endonucleases EcoP1I and EcoP15I P Janscak, U Sandmeier, MD Szczelkun, TA Bickle Journal of molecular biology 306 (3), 417-431, 2001 | 107 | 2001 |
How to get from A to B: strategies for analysing protein motion on DNA SE Halford, MD Szczelkun European Biophysics Journal 31, 257-267, 2002 | 101 | 2002 |
Repercussions of DNA tracking by the type IC restriction endonuclease EcoR124I on linear, circular and catenated substrates. MD Szczelkun, MS Dillingham, P Janscak, K Firman, SE Halford The EMBO Journal 15 (22), 6335-6347, 1996 | 89 | 1996 |
When a helicase is not a helicase: dsDNA tracking by the motor protein EcoR124I LK Stanley, R Seidel, C Van Der Scheer, NH Dekker, MD Szczelkun, ... The EMBO Journal 25 (10), 2230-2239, 2006 | 88 | 2006 |
The helicase-like domains of type III restriction enzymes trigger long-range diffusion along DNA FW Schwarz, J Tóth, K Van Aelst, G Cui, S Clausing, MD Szczelkun, ... Science 340 (6130), 353-356, 2013 | 83 | 2013 |
Motor step size and ATP coupling efficiency of the dsDNA translocase EcoR124I R Seidel, JGP Bloom, C Dekker, MD Szczelkun The EMBO journal 27 (9), 1388-1398, 2008 | 78 | 2008 |
Type III restriction enzymes communicate in 1D without looping between their target sites SP Ramanathan, K Van Aelst, A Sears, LJ Peakman, FM Diffin, ... Proceedings of the National Academy of Sciences 106 (6), 1748-1753, 2009 | 77 | 2009 |
Sequence-Specific Binding of DNA by the EcoRV Restriction and Modification Enzymes with Nucleic Acid and Cofactor Analogs MD Szczelkun, BA Connolly Biochemistry 34 (34), 10724-10733, 1995 | 70 | 1995 |
DNA excision by the SfiI restriction endonuclease TJ Nobbs, MD Szczelkun, LM Wentzell, SE Halford Journal of molecular biology 281 (3), 419-432, 1998 | 69 | 1998 |
Controlling the motor activity of a transcription-repair coupling factor: autoinhibition and the role of RNA polymerase AJ Smith, MD Szczelkun, NJ Savery Nucleic acids research 35 (6), 1802-1811, 2007 | 68 | 2007 |
Continuous assays for DNA translocation using fluorescent triplex dissociation: application to type I restriction endonucleases SE McClelland, DTF Dryden, MD Szczelkun Journal of molecular biology 348 (4), 895-915, 2005 | 64 | 2005 |
Sequence-specific assembly of FtsK hexamers establishes directional translocation on DNA JE Graham, DJ Sherratt, MD Szczelkun Proceedings of the National Academy of Sciences 107 (47), 20263-20268, 2010 | 60 | 2010 |
Recombination by resolvase to analyse DNA communications by the SfiI restriction endonuclease. MD Szczelkun, SE Halford The EMBO Journal 15 (6), 1460-1469, 1996 | 58 | 1996 |
Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I R Seidel, JGP Bloom, J van Noort, CF Dutta, NH Dekker, K Firman, ... The EMBO Journal 24 (23), 4188-4197, 2005 | 55 | 2005 |
Evolutionary ecology and interplay of prokaryotic innate and adaptive immune systems T Dimitriu, MD Szczelkun, ER Westra Current Biology 30 (19), R1189-R1202, 2020 | 54 | 2020 |