Nrf2‐deficient mice are highly susceptible to cigarette smoke‐induced emphysema T Iizuka, Y Ishii, K Itoh, T Kiwamoto, T Kimura, Y Matsuno, Y Morishima, ... Genes to Cells 10 (12), 1113-1125, 2005 | 379 | 2005 |
Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling MK Paul, B Bisht, DO Darmawan, R Chiou, VL Ha, WD Wallace, AT Chon, ... Cell stem cell 15 (2), 199-214, 2014 | 284 | 2014 |
Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema Y Ishii, K Itoh, Y Morishima, T Kimura, T Kiwamoto, T IIzuka, AE Hegab, ... The Journal of Immunology 175 (10), 6968-6975, 2005 | 281 | 2005 |
The role of the receptor for advanced glycation end-products in lung fibrosis M He, H Kubo, K Ishizawa, AE Hegab, Y Yamamoto, H Yamamoto, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (6 …, 2007 | 197 | 2007 |
Transcription factors T-bet and GATA-3 regulate development of airway remodeling T Kiwamoto, Y Ishii, Y Morishima, K Yoh, A Maeda, K Ishizaki, T Iizuka, ... American journal of respiratory and critical care medicine 174 (2), 142-151, 2006 | 163 | 2006 |
Role of 15-deoxyΔ12, 14 prostaglandin J2 and Nrf2 pathways in protection against acute lung injury M Mochizuki, Y Ishii, K Itoh, T Iizuka, Y Morishima, T Kimura, T Kiwamoto, ... American journal of respiratory and critical care medicine 171 (11), 1260-1266, 2005 | 162 | 2005 |
Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential AE Hegab, VL Ha, JL Gilbert, KX Zhang, SP Malkoski, AT Chon, ... Stem Cells 29 (8), 1283-1293, 2011 | 150 | 2011 |
Isolation of alveolar epithelial type II progenitor cells from adult human lungs N Fujino, H Kubo, T Suzuki, C Ota, AE Hegab, M He, S Suzuki, T Suzuki, ... Laboratory Investigation 91 (3), 363-378, 2011 | 144 | 2011 |
Polymorphisms of IL4, IL13, and ADRB2 genes in COPD AE Hegab, T Sakamoto, W Saitoh, HH Massoud, HM Massoud, ... Chest 126 (6), 1832-1839, 2004 | 119 | 2004 |
Isolation and in vitro characterization of basal and submucosal gland duct stem/progenitor cells from human proximal airways AE Hegab, VL Ha, DO Darmawan, JL Gilbert, AT Ooi, YS Attiga, B Bisht, ... Stem cells translational medicine 1 (10), 719-724, 2012 | 92 | 2012 |
Polymorphisms of TNFα, IL1β, and IL1RN genes in chronic obstructive pulmonary disease AE Hegab, T Sakamoto, W Saitoh, A Nomura, Y Ishii, Y Morishima, ... Biochemical and biophysical research communications 329 (4), 1246-1252, 2005 | 91 | 2005 |
Isolation and characterization of murine multipotent lung stem cells AE Hegab, H Kubo, N Fujino, T Suzuki, M He, H Kato, M Yamaya Stem cells and development 19 (4), 523-536, 2010 | 88 | 2010 |
Intranasal HGF administration ameliorates the physiologic and morphologic changes in lung emphysema AE Hegab, H Kubo, M Yamaya, M Asada, M He, N Fujino, S Mizuno, ... Molecular therapy 16 (8), 1417-1426, 2008 | 80 | 2008 |
Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non–small cell lung cancer AT Ooi, V Mah, DW Nickerson, JL Gilbert, VL Ha, AE Hegab, S Horvath, ... Cancer research 70 (16), 6639-6648, 2010 | 73 | 2010 |
Mimicking the niche of lung epithelial stem cells and characterization of several effectors of their in vitro behavior AE Hegab, D Arai, J Gao, A Kuroda, H Yasuda, M Ishii, K Naoki, ... Stem cell research 15 (1), 109-121, 2015 | 67 | 2015 |
Treatment with α-galactosylceramide attenuates the development of bleomycin-induced pulmonary fibrosis T Kimura, Y Ishii, Y Morishima, A Shibuya, K Shibuya, M Taniguchi, ... The journal of Immunology 172 (9), 5782-5789, 2004 | 62 | 2004 |
Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer‐associated fibroblasts AE Hegab, M Ozaki, N Kameyama, J Gao, S Kagawa, H Yasuda, ... the Journal of Pathology 249 (2), 193-205, 2019 | 59 | 2019 |
Suppression of eosinophilic airway inflammation by treatment with α‐galactosylceramide Y Morishima, Y Ishii, T Kimura, A Shibuya, K Shibuya, AE Hegab, T Iizuka, ... European journal of immunology 35 (10), 2803-2814, 2005 | 56 | 2005 |
CLCA1 gene polymorphisms in chronic obstructive pulmonary disease AE Hegab, T Sakamoto, Y Uchida, A Nomura, Y Ishii, Y Morishima, ... Journal of medical genetics 41 (3), e27-e27, 2004 | 54 | 2004 |
Niflumic acid and AG-1478 reduce cigarette smoke-induced mucin synthesis: the role of hCLCA1 AE Hegab, T Sakamoto, A Nomura, Y Ishii, Y Morishima, T Iizuka, ... Chest 131 (4), 1149-1156, 2007 | 48 | 2007 |