关注
Yoong Wearn Lim
Yoong Wearn Lim
未知所在单位机构
在 gene.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals
LA Sanz, SR Hartono, YW Lim, S Steyaert, A Rajpurkar, PA Ginno, X Xu, ...
Molecular cell 63 (1), 167-178, 2016
5112016
GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination
PA Ginno, YW Lim, PL Lott, I Korf, F Chédin
Genome research 23 (10), 1590-1600, 2013
3762013
Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors
E Patin, M Hasan, J Bergstedt, V Rouilly, V Libri, A Urrutia, C Alanio, ...
Nature immunology 19 (3), 302-314, 2018
2722018
Genome-wide DNA hypomethylation and RNA: DNA hybrid accumulation in Aicardi–Goutières syndrome
YW Lim, LA Sanz, X Xu, SR Hartono, F Chedin
Elife 4, e08007, 2015
1862015
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration
YW Lim, H Chen-Harris, O Mayba, S Lianoglou, A Wuster, T Bhangale, ...
Proceedings of the National Academy of Sciences 115 (50), E11701-E11710, 2018
1182018
Massively parallel interrogation and mining of natively paired human TCRαβ repertoires
MJ Spindler, AL Nelson, EK Wagner, N Oppermans, JS Bridgeman, ...
Nature biotechnology 38 (5), 609-619, 2020
582020
Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics
MA Asensio, YW Lim, N Wayham, K Stadtmiller, RC Edgar, J Leong, ...
MAbs 11 (5), 870-883, 2019
322019
Predicting antibody binders and generating synthetic antibodies using deep learning
YW Lim, AS Adler, DS Johnson
MAbs 14 (1), 2069075, 2022
242022
Generation of recombinant hyperimmune globulins from diverse B-cell repertoires
SM Keating, RA Mizrahi, MS Adams, MA Asensio, E Benzie, KP Carter, ...
nature biotechnology 39 (8), 989-999, 2021
202021
Single-cell transcriptomics reveals the effect of PD-L1/TGF-β blockade on the tumor microenvironment
YW Lim, GL Coles, SK Sandhu, DS Johnson, AS Adler, EL Stone
BMC biology 19, 1-17, 2021
172021
Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR
JF Simons, YW Lim, KP Carter, EK Wagner, N Wayham, AS Adler, ...
MAbs 12 (1), 1803646, 2020
142020
Lack of blocking activity in anti-CTLA-4 antibodies reduces toxicity, but not anti-tumor efficacy
EL Stone, KP Carter, EK Wagner, MA Asensio, E Benzie, YY Chiang, ...
BioRxiv, 2021.07. 12.452090, 2021
112021
Preferential identification of agonistic OX40 antibodies by using cell lysate to pan natively paired, humanized mouse-derived yeast surface display libraries
AV Medina-Cucurella, RA Mizrahi, MA Asensio, RC Edgar, J Leong, ...
Antibodies 8 (1), 17, 2019
112019
Capturing and recreating diverse antibody repertoires as multivalent recombinant polyclonal antibody drugs
SM Keating, RA Mizrahi, MS Adams, MA Asensio, E Benzie, KP Carter, ...
bioRxiv, 2020.08. 05.232975, 2020
102020
GMP manufacturing and IND-enabling studies of a recombinant hyperimmune globulin targeting SARS-CoV-2
RA Mizrahi, WY Lin, A Gras, AR Niedecken, EK Wagner, SM Keating, ...
Pathogens 11 (7), 806, 2022
62022
Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics. mAbs 11
MA Asensio, YW Lim, N Wayham, K Stadtmiller, RC Edgar, J Leong, ...
Taylor & Francis, 2019
52019
Natural variation in innate immune cell parameters is preferentially driven by genetic factors
E Patin, M Hasan, J Bergstedt, V Rouilly, V Libri, A Urrutia, C Alanio, ...
press, 0
4
A potent recombinant polyclonal antibody therapeutic for protection against new severe acute respiratory syndrome coronavirus 2 variants of concern
NP Wayham, AR Niedecken, JF Simons, YY Chiang, ...
The Journal of Infectious Diseases 228 (5), 555-563, 2023
22023
Single cell transcriptomics reveals the effect of PD-L1 and TGF-B blockade on the tumor microenvironment
EL Stone, YW Lim, GL Coles, SK Sandhu, DS Johnson, AS Adler
Cancer Research 81 (13_Supplement), 2684-2684, 2021
12021
Anti-vista antibodies and uses thereof
SP Iadonato, T Guillaudeux, EJ Tarcha, DS Johnson, AS Adler, ...
US Patent App. 18/276,417, 2024
2024
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