Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals LA Sanz, SR Hartono, YW Lim, S Steyaert, A Rajpurkar, PA Ginno, X Xu, ... Molecular cell 63 (1), 167-178, 2016 | 511 | 2016 |
GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination PA Ginno, YW Lim, PL Lott, I Korf, F Chédin Genome research 23 (10), 1590-1600, 2013 | 376 | 2013 |
Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors E Patin, M Hasan, J Bergstedt, V Rouilly, V Libri, A Urrutia, C Alanio, ... Nature immunology 19 (3), 302-314, 2018 | 272 | 2018 |
Genome-wide DNA hypomethylation and RNA: DNA hybrid accumulation in Aicardi–Goutières syndrome YW Lim, LA Sanz, X Xu, SR Hartono, F Chedin Elife 4, e08007, 2015 | 186 | 2015 |
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration YW Lim, H Chen-Harris, O Mayba, S Lianoglou, A Wuster, T Bhangale, ... Proceedings of the National Academy of Sciences 115 (50), E11701-E11710, 2018 | 118 | 2018 |
Massively parallel interrogation and mining of natively paired human TCRαβ repertoires MJ Spindler, AL Nelson, EK Wagner, N Oppermans, JS Bridgeman, ... Nature biotechnology 38 (5), 609-619, 2020 | 58 | 2020 |
Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics MA Asensio, YW Lim, N Wayham, K Stadtmiller, RC Edgar, J Leong, ... MAbs 11 (5), 870-883, 2019 | 32 | 2019 |
Predicting antibody binders and generating synthetic antibodies using deep learning YW Lim, AS Adler, DS Johnson MAbs 14 (1), 2069075, 2022 | 24 | 2022 |
Generation of recombinant hyperimmune globulins from diverse B-cell repertoires SM Keating, RA Mizrahi, MS Adams, MA Asensio, E Benzie, KP Carter, ... nature biotechnology 39 (8), 989-999, 2021 | 20 | 2021 |
Single-cell transcriptomics reveals the effect of PD-L1/TGF-β blockade on the tumor microenvironment YW Lim, GL Coles, SK Sandhu, DS Johnson, AS Adler, EL Stone BMC biology 19, 1-17, 2021 | 17 | 2021 |
Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR JF Simons, YW Lim, KP Carter, EK Wagner, N Wayham, AS Adler, ... MAbs 12 (1), 1803646, 2020 | 14 | 2020 |
Lack of blocking activity in anti-CTLA-4 antibodies reduces toxicity, but not anti-tumor efficacy EL Stone, KP Carter, EK Wagner, MA Asensio, E Benzie, YY Chiang, ... BioRxiv, 2021.07. 12.452090, 2021 | 11 | 2021 |
Preferential identification of agonistic OX40 antibodies by using cell lysate to pan natively paired, humanized mouse-derived yeast surface display libraries AV Medina-Cucurella, RA Mizrahi, MA Asensio, RC Edgar, J Leong, ... Antibodies 8 (1), 17, 2019 | 11 | 2019 |
Capturing and recreating diverse antibody repertoires as multivalent recombinant polyclonal antibody drugs SM Keating, RA Mizrahi, MS Adams, MA Asensio, E Benzie, KP Carter, ... bioRxiv, 2020.08. 05.232975, 2020 | 10 | 2020 |
GMP manufacturing and IND-enabling studies of a recombinant hyperimmune globulin targeting SARS-CoV-2 RA Mizrahi, WY Lin, A Gras, AR Niedecken, EK Wagner, SM Keating, ... Pathogens 11 (7), 806, 2022 | 6 | 2022 |
Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics. mAbs 11 MA Asensio, YW Lim, N Wayham, K Stadtmiller, RC Edgar, J Leong, ... Taylor & Francis, 2019 | 5 | 2019 |
Natural variation in innate immune cell parameters is preferentially driven by genetic factors E Patin, M Hasan, J Bergstedt, V Rouilly, V Libri, A Urrutia, C Alanio, ... press, 0 | 4 | |
A potent recombinant polyclonal antibody therapeutic for protection against new severe acute respiratory syndrome coronavirus 2 variants of concern NP Wayham, AR Niedecken, JF Simons, YY Chiang, ... The Journal of Infectious Diseases 228 (5), 555-563, 2023 | 2 | 2023 |
Single cell transcriptomics reveals the effect of PD-L1 and TGF-B blockade on the tumor microenvironment EL Stone, YW Lim, GL Coles, SK Sandhu, DS Johnson, AS Adler Cancer Research 81 (13_Supplement), 2684-2684, 2021 | 1 | 2021 |
Anti-vista antibodies and uses thereof SP Iadonato, T Guillaudeux, EJ Tarcha, DS Johnson, AS Adler, ... US Patent App. 18/276,417, 2024 | | 2024 |