Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia FP Pankowicz, M Barzi, X Legras, L Hubert, T Mi, JA Tomolonis, ... Nature communications 7 (1), 12642, 2016 | 153 | 2016 |
Neuroblastoma pathogenesis: deregulation of embryonic neural crest development JA Tomolonis, S Agarwal, JM Shohet Cell and tissue research 372 (2), 245-262, 2018 | 134 | 2018 |
A broad-spectrum infection diagnostic that detects pathogen-associated molecular patterns (PAMPs) in whole blood M Cartwright, M Rottman, NI Shapiro, B Seiler, P Lombardo, N Gamini, ... EBioMedicine 9, 217-227, 2016 | 45 | 2016 |
A KLF4-DYRK2–mediated pathway regulating self-renewal in CML stem cells CS Park, AH Lewis, TJ Chen, CS Bridges, Y Shen, K Suppipat, M Puppi, ... Blood, The Journal of the American Society of Hematology 134 (22), 1960-1972, 2019 | 41 | 2019 |
Non‐muscle myosin‐IIA is critical for podocyte f‐actin organization, contractility, and attenuation of cell motility PA Bondzie, HA Chen, MZ Cao, JA Tomolonis, F He, MR Pollak, ... Cytoskeleton 73 (8), 377-395, 2016 | 23 | 2016 |
Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma JA Tomolonis, X Xu, KH Dholakia, C Zhang, L Guo, AN Courtney, S Wang, ... Journal for Immunotherapy of Cancer 11 (3), 2023 | 3 | 2023 |
Methods and compositions for improving detection and/or capture of a target entity M Super, MJ Cartwright, MM Rottman, JA Tomolonis US Patent 10,551,379, 2020 | 3 | 2020 |
Epigenetic regulation of neuroblastoma tumorigenicity through MLL1 and JMJD3 modulation in cancer stem cells S Agarwal, Z Chen, JA Tomolonis, SA Vasudevan, JM Shohet Cancer Research 77 (13_Supplement), 4781-4781, 2017 | 2 | 2017 |
KLF4 promotes self-renewal by repressing DYRK2-mediated degradation of c-Myc in leukemic stem cells: development of targeted therapy CS Park, Y Shen, K Suppipat, J Tomolonis, M Puppi, TA Mistretta, L Ma, ... Cancer research 76 (14_Supplement), 3334-3334, 2016 | 1 | 2016 |
Methods and compositions for improving detection and/or capture of a target entity M Super, MJ Cartwright, MM ROTTMAN, JA TOMOLONIS | 1 | 2014 |
TNFa SIGNALING TRIGGERS TUMOR-PROMOTING INFLAMMATION THAT CAN BE TARGETED TO THERAPY LS Metelitsa, J Tomolonis US Patent App. 17/907,312, 2023 | | 2023 |
Assays for antimicrobial activity and applications thereof MJ Cartwright, N Gamini, DE Ingber, MM Rottman, M Super, JA Tomolonis, ... US Patent App. 17/528,456, 2022 | | 2022 |
Assays for antimicrobial activity and applications thereof MJ Cartwright, N Gamini, DE Ingber, M Rottman, M Super, JA Tomolonis, ... US Patent 11,209,432, 2021 | | 2021 |
Methods and compositions for improving detection and/or capture of a target entity M Super, MJ Cartwright, MM Rottman, JA Tomolonis US Patent App. 16/713,440, 2020 | | 2020 |
The TNFR1/mTNFα signaling axis initiates tumor-promoting inflammation and is associated with poor outcome in neuroblastoma JA Tomolonis, H Ngai, A Courtney, LS Metelitsa The Journal of Immunology 202 (1_Supplement), 195.27-195.27, 2019 | | 2019 |
Abstract B21: Epigenetic modifiers MLL1 and JMJD3 regulate neuroblastoma tumorigenicity by maintaining a cancer stem cell-like population S Agarwal, J Tomolonis, S Vasudevan, J Shohet Cancer Research 78 (19_Supplement), B21-B21, 2018 | | 2018 |
Pharmacologic inhibition of SIAH2 stabilizes DYRK2 and inhibits survival and self-renewal in chronic myeloid leukemia (CML) leukemic stem cells CS Park, Y Shen, A Lewis, K Suppipat, M Puppi, J Tomolonis, T Chen, ... Cancer Research 78 (13_Supplement), 145-145, 2018 | | 2018 |
Vitamin K3 (menadione) Induces Cytotoxicity in Chronic Myeloid Leukemia Stem Cells By Upregulating DYRK2 through the Inhibition of SIAH2 Ubiquitin Ligase CS Park, Y Shen, AH Lewis, K Suppipat, M Puppi, J Tomolonis, TJ Chen, ... Blood 130, 4171, 2017 | | 2017 |
Assays for antimicrobial activity and applications thereof MJ Cartwright, N Gamini, DE Ingber, M Rottman, M Super, JA Tomolonis, ... US Patent 9,791,440, 2017 | | 2017 |
DYRK2 Inhibits the Self-Renewal of Leukemic Stem Cells in Chronic Myeloid Leukemia By Inducing Degradation of c-Myc Downstream of the Reprogramming Factor KLF4 CS Park, Y Shen, K Suppipat, A Lewis, J Tomolonis, M Puppi, TA Mistretta, ... Blood, The Journal of the American Society of Hematology 128 (22), 1879-1879, 2016 | | 2016 |