Preference of conjugated bile acids over unconjugated bile acids as substrates for OATP1B1 and OATP1B3 T Suga, H Yamaguchi, T Sato, M Maekawa, J Goto, N Mano PloS one 12 (1), e0169719, 2017 | 116 | 2017 |
Identification of novel bile acids as biomarkers for the early diagnosis of Niemann‐Pick C disease F Mazzacuva, P Mills, K Mills, S Camuzeaux, P Gissen, ER Nicoli, ... FEBS letters 590 (11), 1651-1662, 2016 | 106 | 2016 |
Unconjugated bile acids in rat brain: Analytical method based on LC/ESI-MS/MS with chemical derivatization and estimation of their origin by comparison to serum levels T Higashi, S Watanabe, K Tomaru, W Yamazaki, K Yoshizawa, S Ogawa, ... Steroids 125, 107-113, 2017 | 79 | 2017 |
Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis T Suga, H Yamaguchi, J Ogura, S Shoji, M Maekawa, N Mano Toxicology and Applied Pharmacology 379, 114664, 2019 | 63 | 2019 |
Activation of the hypoxia inducible factor 1α subunit pathway in steatotic liver contributes to formation of cholesterol gallstones Y Asai, T Yamada, S Tsukita, K Takahashi, M Maekawa, M Honma, ... Gastroenterology 152 (6), 1521-1535. e8, 2017 | 54 | 2017 |
LC/ESI-MS/MS analysis of urinary 3β-sulfooxy-7β-N-acetylglucosaminyl-5-cholen-24-oic acid and its amides: New biomarkers for the detection of Niemann–Pick type C disease M Maekawa, Y Misawa, A Sotoura, H Yamaguchi, M Togawa, K Ohno, ... Steroids 78 (10), 967-972, 2013 | 48 | 2013 |
Tandem mass spectrometric characterization of bile acids and steroid conjugates based on low-energy collision-induced dissociation M Maekawa, M Shimada, T Iida, J Goto, N Mano Steroids 80, 80-91, 2014 | 47 | 2014 |
Functional characterization of 21 allelic variants of dihydropyrimidine dehydrogenase identified in 1070 Japanese individuals E Hishinuma, Y Narita, S Saito, M Maekawa, F Akai, Y Nakanishi, ... Drug Metabolism and Disposition 46 (8), 1083-1090, 2018 | 42 | 2018 |
A quantitative HPLC-UV method for determination of serum sorafenib and sorafenib N-oxide and its application in hepatocarcinoma patients M Shimada, H Okawa, T Maejima, T Yanagi, K Hisamichi, M Matsuura, ... The Tohoku journal of experimental medicine 233 (2), 103-112, 2014 | 35 | 2014 |
Simultaneous analysis of oral anticancer drugs for renal cell carcinoma in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry S Takasaki, M Tanaka, M Kikuchi, M Maekawa, Y Kawasaki, A Ito, Y Arai, ... Biomedical Chromatography 32 (6), e4184, 2018 | 32 | 2018 |
Monitoring serum levels of sorafenib and its N-oxide is essential for long-term sorafenib treatment of patients with hepatocellular carcinoma M Shimada, H Okawa, Y Kondo, T Maejima, Y Kataoka, K Hisamichi, ... The Tohoku journal of experimental medicine 237 (3), 173-182, 2015 | 32 | 2015 |
Structural determination of lysosphingomyelin-509 and discovery of novel class lipids from patients with Niemann–Pick disease type C M Maekawa, I Jinnoh, Y Matsumoto, A Narita, R Mashima, H Takahashi, ... International Journal of Molecular Sciences 20 (20), 5018, 2019 | 30 | 2019 |
Value of global metabolomics in association with diagnosis and clinicopathological factors of renal cell carcinoma T Sato, Y Kawasaki, M Maekawa, S Takasaki, D Saigusa, H Ota, ... International journal of cancer 145 (2), 484-493, 2019 | 30 | 2019 |
Functional characterization of 40 CYP3A4 variants by assessing midazolam 1′-hydroxylation and testosterone 6β-hydroxylation M Kumondai, EMG Rico, E Hishinuma, A Ueda, S Saito, D Saigusa, ... Drug Metabolism and Disposition 49 (3), 212-220, 2021 | 28 | 2021 |
Functional characterization of 34 CYP2A6 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation activities H Hosono, M Kumondai, M Maekawa, H Yamaguchi, N Mano, A Oda, ... Drug Metabolism and Disposition 45 (3), 279-285, 2017 | 28 | 2017 |
Functional characterization of 21 CYP2C19 allelic variants for clopidogrel 2-oxidation M Takahashi, T Saito, M Ito, C Tsukada, Y Katono, H Hosono, M Maekawa, ... The Pharmacogenomics Journal 15 (1), 26-32, 2015 | 28 | 2015 |
Focused metabolomics using liquid chromatography/electrospray ionization tandem mass spectrometry for analysis of urinary conjugated cholesterol metabolites from patients with … M Maekawa, M Shimada, K Ohno, M Togawa, H Nittono, T Iida, ... Annals of Clinical Biochemistry 52 (5), 576-587, 2015 | 27 | 2015 |
Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS Y Kanemitsu, E Mishima, M Maekawa, Y Matsumoto, D Saigusa, ... Scientific Reports 9 (1), 19075, 2019 | 24 | 2019 |
Investigation of diagnostic performance of five urinary cholesterol metabolites for Niemann-Pick disease type C M Maekawa, I Jinnoh, A Narita, T Iida, D Saigusa, A Iwahori, H Nittono, ... Journal of Lipid Research 60 (12), 2074-2081, 2019 | 23 | 2019 |
Combining [13C6]‐phenylisothiocyanate and the Edman degradation reaction: a possible breakthrough for absolute quantitative proteomics together with protein … T Oe, M Maekawa, R Satoh, SH Lee, T Goto Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2010 | 23 | 2010 |