Dose-dependent immunomodulatory effect of human stem cells from amniotic membrane: a comparison with human mesenchymal stem cells from adipose tissue S Wolbank, A Peterbauer, M Fahrner, S Hennerbichler, M Van Griensven, ... Tissue engineering 13 (6), 1173-1183, 2007 | 510 | 2007 |
Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation M Muik, I Frischauf, I Derler, M Fahrner, J Bergsmann, P Eder, R Schindl, ... Journal of Biological Chemistry 283 (12), 8014-8022, 2008 | 500 | 2008 |
A cytosolic homomerization and a modulatory domain within STIM1 C terminus determine coupling to ORAI1 channels M Muik, M Fahrner, I Derler, R Schindl, J Bergsmann, I Frischauf, ... Journal of biological chemistry 284 (13), 8421-8426, 2009 | 398 | 2009 |
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation M Muik, M Fahrner, R Schindl, P Stathopulos, I Frischauf, I Derler, P Plenk, ... The EMBO journal 30 (9), 1678-1689, 2011 | 283 | 2011 |
STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry PB Stathopulos, R Schindl, M Fahrner, L Zheng, GM Gasmi-Seabrook, ... Nature communications 4 (1), 2963, 2013 | 244 | 2013 |
Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1–3 channels by a STIM1 coiled-coil mutant I Frischauf, M Muik, I Derler, J Bergsmann, M Fahrner, R Schindl, ... Journal of biological chemistry 284 (32), 21696-21706, 2009 | 198 | 2009 |
2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size R Schindl, J Bergsmann, I Frischauf, I Derler, M Fahrner, M Muik, R Fritsch, ... Journal of Biological Chemistry 283 (29), 20261-20267, 2008 | 166 | 2008 |
A Ca2+ Release-activated Ca2+ (CRAC) Modulatory Domain (CMD) within STIM1 Mediates Fast Ca2+-dependent Inactivation of ORAI1 Channels*♦ I Derler, M Fahrner, M Muik, B Lackner, R Schindl, K Groschner, ... Journal of biological chemistry 284 (37), 24933-24938, 2009 | 162 | 2009 |
The Extended Transmembrane Orai1 N-Terminal (ETON) Region Combines Binding Interface and Gate for Orai1 Activation by STIM1*♦ I Derler, P Plenk, M Fahrner, M Muik, I Jardin, R Schindl, HJ Gruber, ... Journal of Biological Chemistry 288 (40), 29025-29034, 2013 | 152 | 2013 |
A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1) M Fahrner, M Muik, R Schindl, C Butorac, P Stathopulos, L Zheng, I Jardin, ... Journal of Biological Chemistry 289 (48), 33231-33244, 2014 | 151 | 2014 |
The STIM/Orai coupling machinery I Frischauf, R Schindl, I Derler, J Bergsmann, M Fahrner, C Romanin Channels 2 (4), 261-268, 2008 | 145 | 2008 |
Store-Independent Orai1/3 Channels Activated by Intracrine LeukotrieneC4 Role in Neointimal Hyperplasia JC González-Cobos, X Zhang, W Zhang, B Ruhle, RK Motiani, R Schindl, ... Circulation research 112 (7), 1013-1025, 2013 | 143 | 2013 |
Resting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cells J Madl, J Weghuber, R Fritsch, I Derler, M Fahrner, I Frischauf, B Lackner, ... Journal of Biological Chemistry 285 (52), 41135-41142, 2010 | 124 | 2010 |
Mechanistic view on domains mediating STIM1–Orai coupling M Fahrner, M Muik, I Derler, R Schindl, R Fritsch, I Frischauf, C Romanin Immunological reviews 231 (1), 99-112, 2009 | 123 | 2009 |
Cholesterol modulates Orai1 channel function I Derler, I Jardin, PB Stathopulos, M Muik, M Fahrner, V Zayats, ... Science signaling 9 (412), ra10-ra10, 2016 | 101 | 2016 |
Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant I Derler, M Fahrner, O Carugo, M Muik, J Bergsmann, R Schindl, ... Journal of Biological Chemistry 284 (23), 15903-15915, 2009 | 90 | 2009 |
Ca2+ release-activated Ca2+ (CRAC) current, structure, and function M Muik, R Schindl, M Fahrner, C Romanin Cellular and Molecular Life Sciences 69, 4163-4176, 2012 | 87 | 2012 |
The STIM1/Orai signaling machinery M Fahrner, I Derler, I Jardin, C Romanin Channels 7 (5), 330-343, 2013 | 76 | 2013 |
Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation M Maus, A Jairaman, PB Stathopulos, M Muik, M Fahrner, C Weidinger, ... Proceedings of the National Academy of Sciences 112 (19), 6206-6211, 2015 | 71 | 2015 |
Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels X Zhang, JC González-Cobos, R Schindl, M Muik, B Ruhle, RK Motiani, ... Molecular and cellular biology, 2013 | 64 | 2013 |