Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin T Masuda, X Wang, M Maeda, MC Canver, F Sher, APW Funnell, C Fisher, ... Science 351 (6270), 285-289, 2016 | 369 | 2016 |
Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding GE Martyn, B Wienert, L Yang, M Shah, LJ Norton, J Burdach, R Kurita, ... Nature genetics 50 (4), 498-503, 2018 | 287 | 2018 |
Wake-up sleepy gene: reactivating fetal globin for β-hemoglobinopathies B Wienert, GE Martyn, APW Funnell, KGR Quinlan, M Crossley Trends in Genetics 34 (12), 927-940, 2018 | 127 | 2018 |
KLF1 drives the expression of fetal hemoglobin in British HPFH B Wienert, GE Martyn, R Kurita, Y Nakamura, KGR Quinlan, M Crossley Blood, The Journal of the American Society of Hematology 130 (6), 803-807, 2017 | 98 | 2017 |
A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site GE Martyn, B Wienert, R Kurita, Y Nakamura, KGR Quinlan, M Crossley Blood, The Journal of the American Society of Hematology 133 (8), 852-856, 2019 | 68 | 2019 |
The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y GE Martyn, KGR Quinlan, M Crossley Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1860 (5), 525-536, 2017 | 48 | 2017 |
Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression SK Topfer, R Feng, P Huang, LC Ly, GE Martyn, GA Blobel, MJ Weiss, ... Blood, The Journal of the American Society of Hematology 139 (14), 2107-2118, 2022 | 46 | 2022 |
Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells APW Funnell, D Vernimmen, WF Lim, KS Mak, B Wienert, GE Martyn, ... BMC molecular biology 15, 1-12, 2014 | 18 | 2014 |
Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress FL Byrne, EM Olzomer, GR Marriott, LE Quek, A Katen, J Su, ME Nelson, ... Redox biology 28, 101374, 2020 | 15 | 2020 |
Rewriting regulatory DNA to dissect and reprogram gene expression GE Martyn, MT Montgomery, H Jones, K Guo, BR Doughty, J Linder, ... bioRxiv, 2023 | 11 | 2023 |
Identification of protein Isoforms using reference databases built from Long and Short Read RNA-Sequencing AP Tay, JJ Hamey, GE Martyn, LOW Wilson, MR Wilkins Journal of Proteome Research 21 (7), 1628-1639, 2022 | 5 | 2022 |
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin T Masuda, X Wang, M Maeda, MC Canver, F Sher, APW Funnell, C Fisher, ... Blood 126 (23), 2, 2015 | 2 | 2015 |
Hydroxyurea reduces the levels of the fetal globin gene repressors ZBTB7A/LRF and BCL11A in erythroid cells in vitro GE Martyn, PA Doerfler, Y Yao, KGR Quinlan, MJ Weiss, M Crossley Journal of Sickle Cell Disease 1 (1), yoae008, 2024 | 1 | 2024 |
Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity A Tervi, M Ramste, E Abner, P Cheng, JM Lane, M Maher, J Valliere, ... Cell Genomics 4 (9), 2024 | | 2024 |
Revealing the mechanism of the-115 gamma-globin site Hereditary Persistence of Foetal Haemoglobin mutations G Martyn UNSW Sydney, 2018 | | 2018 |