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Gabriella E. Martyn
Gabriella E. Martyn
在 stanford.edu 的电子邮件经过验证
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Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin
T Masuda, X Wang, M Maeda, MC Canver, F Sher, APW Funnell, C Fisher, ...
Science 351 (6270), 285-289, 2016
3692016
Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding
GE Martyn, B Wienert, L Yang, M Shah, LJ Norton, J Burdach, R Kurita, ...
Nature genetics 50 (4), 498-503, 2018
2872018
Wake-up sleepy gene: reactivating fetal globin for β-hemoglobinopathies
B Wienert, GE Martyn, APW Funnell, KGR Quinlan, M Crossley
Trends in Genetics 34 (12), 927-940, 2018
1272018
KLF1 drives the expression of fetal hemoglobin in British HPFH
B Wienert, GE Martyn, R Kurita, Y Nakamura, KGR Quinlan, M Crossley
Blood, The Journal of the American Society of Hematology 130 (6), 803-807, 2017
982017
A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site
GE Martyn, B Wienert, R Kurita, Y Nakamura, KGR Quinlan, M Crossley
Blood, The Journal of the American Society of Hematology 133 (8), 852-856, 2019
682019
The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y
GE Martyn, KGR Quinlan, M Crossley
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1860 (5), 525-536, 2017
482017
Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression
SK Topfer, R Feng, P Huang, LC Ly, GE Martyn, GA Blobel, MJ Weiss, ...
Blood, The Journal of the American Society of Hematology 139 (14), 2107-2118, 2022
462022
Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells
APW Funnell, D Vernimmen, WF Lim, KS Mak, B Wienert, GE Martyn, ...
BMC molecular biology 15, 1-12, 2014
182014
Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress
FL Byrne, EM Olzomer, GR Marriott, LE Quek, A Katen, J Su, ME Nelson, ...
Redox biology 28, 101374, 2020
152020
Rewriting regulatory DNA to dissect and reprogram gene expression
GE Martyn, MT Montgomery, H Jones, K Guo, BR Doughty, J Linder, ...
bioRxiv, 2023
112023
Identification of protein Isoforms using reference databases built from Long and Short Read RNA-Sequencing
AP Tay, JJ Hamey, GE Martyn, LOW Wilson, MR Wilkins
Journal of Proteome Research 21 (7), 1628-1639, 2022
52022
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin
T Masuda, X Wang, M Maeda, MC Canver, F Sher, APW Funnell, C Fisher, ...
Blood 126 (23), 2, 2015
22015
Hydroxyurea reduces the levels of the fetal globin gene repressors ZBTB7A/LRF and BCL11A in erythroid cells in vitro
GE Martyn, PA Doerfler, Y Yao, KGR Quinlan, MJ Weiss, M Crossley
Journal of Sickle Cell Disease 1 (1), yoae008, 2024
12024
Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity
A Tervi, M Ramste, E Abner, P Cheng, JM Lane, M Maher, J Valliere, ...
Cell Genomics 4 (9), 2024
2024
Revealing the mechanism of the-115 gamma-globin site Hereditary Persistence of Foetal Haemoglobin mutations
G Martyn
UNSW Sydney, 2018
2018
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