Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 607 | 2020 |
Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment I Kufareva, M Rueda, V Katritch, RC Stevens, R Abagyan Structure 19 (8), 1108-1126, 2011 | 343 | 2011 |
Closing in on the resting state of the Shaker K+ channel MM Pathak, V Yarov-Yarovoy, G Agarwal, B Roux, P Barth, S Kohout, ... Neuron 56 (1), 124-140, 2007 | 325 | 2007 |
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008 M Michino, E Abola, GPCR Dock 2008 Participants, CL Brooks III, ... Nature Reviews Drug Discovery 8 (6), 455-463, 2009 | 303 | 2009 |
Toward high-resolution prediction and design of transmembrane helical protein structures P Barth, J Schonbrun, D Baker Proceedings of the National Academy of Sciences 104 (40), 15682-15687, 2007 | 271 | 2007 |
Protein–Protein Interactions Governing Septin Heteropentamer Assembly and Septin Filament Organization in Saccharomyces cerevisiae M Versele, B Gullbrand, MJ Shulewitz, VJ Cid, S Bahmanyar, RE Chen, ... Molecular biology of the cell 15 (10), 4568-4583, 2004 | 199 | 2004 |
Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges I Kufareva, V Katritch, RC Stevens, R Abagyan Structure 22 (8), 1120-1139, 2014 | 183 | 2014 |
Prediction of membrane protein structures with complex topologies using limited constraints P Barth, B Wallner, D Baker Proceedings of the National Academy of Sciences 106 (5), 1409-1414, 2009 | 180 | 2009 |
Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane J Yin, KYM Chen, MJ Clark, M Hijazi, P Kumari, X Bai, RK Sunahara, ... Nature 584 (7819), 125-129, 2020 | 168 | 2020 |
The structure of a receptor with two associating transmembrane domains on the cell surface: integrin αIIbβ3 J Zhu, BH Luo, P Barth, J Schonbrun, D Baker, TA Springer Molecular cell 34 (2), 234-249, 2009 | 166 | 2009 |
Platon: identification and characterization of bacterial plasmid contigs in short-read draft assemblies exploiting protein sequence-based replicon distribution scores O Schwengers, P Barth, L Falgenhauer, T Hain, T Chakraborty, ... Microbial genomics 6 (10), e000398, 2020 | 132 | 2020 |
Ferredoxin reduction by photosystem I from Synechocystis sp. PCC 6803: toward an understanding of the respective roles of subunits PsaD and PsaE in ferredoxin binding P Barth, B Lagoutte, P Sétif Biochemistry 37 (46), 16233-16241, 1998 | 78 | 1998 |
An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function L Wang, K Pang, K Han, CJ Adamski, W Wang, L He, JK Lai, VV Bondar, ... Molecular psychiatry 25 (10), 2534-2555, 2020 | 69 | 2020 |
Survivin-specific T cell receptor targets tumor but not T cells C Arber, X Feng, H Abhyankar, E Romero, MF Wu, HE Heslop, P Barth, ... The Journal of clinical investigation 125 (1), 157-168, 2015 | 68 | 2015 |
Computational design of G Protein-Coupled Receptor allosteric signal transductions KYM Chen, D Keri, P Barth Nature Chemical Biology 16 (1), 77-86, 2020 | 59 | 2020 |
Accurate, conformation-dependent predictions of solvent effects on protein ionization constants P Barth, T Alber, PB Harbury Proceedings of the National Academy of Sciences 104 (12), 4898-4903, 2007 | 54 | 2007 |
Naturally evolved G protein-coupled receptors adopt metastable conformations KYM Chen, F Zhou, BG Fryszczyn, P Barth Proceedings of the National Academy of Sciences 109 (33), 13284-13289, 2012 | 52 | 2012 |
Essential role of a single arginine of photosystem I in stabilizing the electron transfer complex with ferredoxin P Barth, I Guillouard, P Sétif, B Lagoutte Journal of Biological Chemistry 275 (10), 7030-7036, 2000 | 51 | 2000 |
Evolutionary-guided de novo structure prediction of self-associated transmembrane helical proteins with near-atomic accuracy Y Wang, P Barth Nature Communications 6 (1), 7196, 2015 | 41 | 2015 |
Computational design of ligand-binding membrane receptors with high selectivity X Feng, J Ambia, KYM Chen, M Young, P Barth Nature chemical biology 13 (7), 715-723, 2017 | 39 | 2017 |