Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility T Raj, YI Li, G Wong, J Humphrey, M Wang, S Ramdhani, YC Wang, B Ng, ... Nature genetics 50 (11), 1584-1592, 2018 | 341 | 2018 |
Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells I Gupta, PG Collier, B Haase, A Mahfouz, A Joglekar, T Floyd, ... Nature biotechnology 36 (12), 1197-1202, 2018 | 286 | 2018 |
Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila VO Sysoev, B Fischer, CK Frese, I Gupta, J Krijgsveld, MW Hentze, ... Nature communications 7 (1), 12128, 2016 | 154 | 2016 |
Alternative polyadenylation diversifies post‐transcriptional regulation by selective RNA–protein interactions I Gupta, S Clauder‐Münster, B Klaus, AI Järvelin, RS Aiyar, V Benes, ... Molecular systems biology 10 (2), 719, 2014 | 125 | 2014 |
Rrp6p controls mRNA poly (A) tail length and its decoration with poly (A) binding proteins M Schmid, MB Poulsen, P Olszewski, V Pelechano, C Saguez, I Gupta, ... Molecular cell 47 (2), 267-280, 2012 | 95 | 2012 |
Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism M Kapoor, JC Wang, SP Farris, Y Liu, J McClintick, I Gupta, JL Meyers, ... Translational psychiatry 9 (1), 89, 2019 | 82 | 2019 |
Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome H Tilgner, F Jahanbani, I Gupta, P Collier, E Wei, M Rasmussen, ... Genome research 28 (2), 231-242, 2018 | 74 | 2018 |
The Not5 subunit of the ccr4-not complex connects transcription and translation Z Villanyi, V Ribaud, S Kassem, OO Panasenko, Z Pahi, I Gupta, ... PLoS genetics 10 (10), e1004569, 2014 | 69 | 2014 |
The nuclear polyA-binding protein Nab2p is essential for mRNA production M Schmid, P Olszewski, V Pelechano, I Gupta, LM Steinmetz, TH Jensen Cell reports 12 (1), 128-139, 2015 | 67 | 2015 |
Protein abundance control by non-coding antisense transcription F Huber, D Bunina, I Gupta, A Khmelinskii, M Meurer, P Theer, ... Cell reports 15 (12), 2625-2636, 2016 | 60 | 2016 |
Alzheimer's-associated PU. 1 expression levels regulate microglial inflammatory response AA Pimenova, M Herbinet, I Gupta, SI Machlovi, KR Bowles, E Marcora, ... Neurobiology of disease 148, 105217, 2021 | 58 | 2021 |
Translational capacity of a cell is determined during transcription elongation via the Ccr4-Not complex I Gupta, Z Villanyi, S Kassem, C Hughes, OO Panasenko, LM Steinmetz, ... Cell reports 15 (8), 1782-1794, 2016 | 53 | 2016 |
A high‐throughput C h IP‐S eq for large‐scale chromatin studies CD Chabbert, SH Adjalley, B Klaus, ES Fritsch, I Gupta, V Pelechano, ... Molecular systems biology 11 (1), 777, 2015 | 39 | 2015 |
Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle A Jordán-Pla, I Gupta, L de Miguel-Jiménez, LM Steinmetz, S Chavez, ... Nucleic acids research 43 (2), 787-802, 2015 | 35 | 2015 |
Hedgehog signaling demarcates a niche of fibrogenic peribiliary mesenchymal cells V Gupta, I Gupta, J Park, Y Bram, RE Schwartz Gastroenterology 159 (2), 624-638. e9, 2020 | 28 | 2020 |
Detrimental effect of diabetes and hypertension on the severity and mortality of COVID-19 infection: A multi-center case-control study from India SK Jayaswal, S Singh, PS Malik, SK Venigalla, P Gupta, SN Samaga, ... Diabetes & Metabolic Syndrome: Clinical Research & Reviews 15 (5), 102248, 2021 | 24 | 2021 |
Single-cell RNA sequencing reveals cellular heterogeneity and stage transition under temperature stress in synchronized Plasmodium falciparum cells M Rawat, A Srivastava, S Johri, I Gupta, K Karmodiya Microbiology spectrum 9 (1), 10.1128/spectrum. 00008-21, 2021 | 21 | 2021 |
Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality A Budhraja, A Basu, A Gheware, D Abhilash, S Rajagopala, S Pakala, ... Disease Models & Mechanisms 15 (5), dmm049572, 2022 | 19 | 2022 |
Dissecting the nutrient partitioning mechanism in rice grain using spatially resolved gene expression profiling H Ram, A Singh, M Katoch, R Kaur, S Sardar, S Palia, R Satyam, H Sonah, ... Journal of Experimental Botany 72 (6), 2212-2230, 2021 | 13 | 2021 |
Integrative analyses of splicing in the aging brain: Role in susceptibility to Alzheimer’s disease T Raj, YI Li, G Wong, S Ramdhani, Y Wang, B Ng, M Wang, I Gupta, ... BioRxiv, 174565, 2017 | 12 | 2017 |