Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. PJ Sime, Z Xing, FL Graham, KG Csaky, J Gauldie The Journal of clinical investigation 100 (4), 768-776, 1997 | 1288 | 1997 |
Fibrosis of the lung and other tissues: new concepts in pathogenesis and treatment PJ Sime, KMA O'Reilly Clinical immunology 99 (3), 308-319, 2001 | 479 | 2001 |
PPARγ agonists inhibit TGF-β induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis HA Burgess, LE Daugherty, TH Thatcher, HF Lakatos, DM Ray, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (6 …, 2005 | 412 | 2005 |
Transfer of tumor necrosis factor-α to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-β1 and … PJ Sime, RA Marr, D Gauldie, Z Xing, BR Hewlett, FL Graham, J Gauldie The American journal of pathology 153 (3), 825-832, 1998 | 383 | 1998 |
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation AC Bakker, FAJ Van De Loo, HM Van Beuningen, P Sime, P Van Lent, ... Osteoarthritis and cartilage 9 (2), 128-136, 2001 | 364 | 2001 |
Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung M Kolb, PJ Margetts, PJ Sime, J Gauldie American Journal of Physiology-Lung Cellular and Molecular Physiology 280 (6 …, 2001 | 341 | 2001 |
Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-β RM Kottmann, AA Kulkarni, KA Smolnycki, E Lyda, T Dahanayake, ... American journal of respiratory and critical care medicine 186 (8), 740-751, 2012 | 340 | 2012 |
Asbestos-related lung disease KMA O'REILLY, AM Mclaughlin, WS Beckett, PJ Sime American family physician 75 (5), 683-688, 2007 | 319 | 2007 |
An official American Thoracic Society workshop report: use of animal models for the preclinical assessment of potential therapies for pulmonary fibrosis RG Jenkins, BB Moore, RC Chambers, O Eickelberg, M Königshoff, ... American journal of respiratory cell and molecular biology 56 (5), 667-679, 2017 | 313 | 2017 |
Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer CA Martey, SJ Pollock, CK Turner, KMA O'Reilly, CJ Baglole, RP Phipps, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 287 (5 …, 2004 | 282 | 2004 |
Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin M Kolb, PJ Margetts, T Galt, PJ Sime, Z Xing, M Schmidt, J Gauldie American journal of respiratory and critical care medicine 163 (3), 770-777, 2001 | 279 | 2001 |
TGF-β, Smad3 and the process of progressive fibrosis J Gauldie, P Bonniaud, P Sime, K Ask, M Kolb Biochemical Society Transactions 35 (4), 661-664, 2007 | 252 | 2007 |
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, ... American journal of respiratory and critical care medicine 189 (2), 214-222, 2014 | 251 | 2014 |
PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis AA Kulkarni, TH Thatcher, KC Olsen, SB Maggirwar, RP Phipps, PJ Sime PloS one 6 (1), e15909, 2011 | 243 | 2011 |
Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? D Panigrahy, MM Gilligan, S Huang, A Gartung, I Cortés-Puch, PJ Sime, ... Cancer and metastasis reviews 39, 337-340, 2020 | 236 | 2020 |
PPARγ and the Innate Immune System Mediate the Resolution of Inflammation A Croasdell, PF Duffney, N Kim, SH Lacy, PJ Sime, RP Phipps PPAR research 2015 (1), 549691, 2015 | 232 | 2015 |
A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation HM Hsiao, RE Sapinoro, TH Thatcher, A Croasdell, EP Levy, RA Fulton, ... PloS one 8 (3), e58258, 2013 | 224 | 2013 |
Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-κB … TH Thatcher, SB Maggirwar, CJ Baglole, HF Lakatos, TA Gasiewicz, ... The American journal of pathology 170 (3), 855-864, 2007 | 212 | 2007 |
Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation HF Lakatos, HA Burgess, TH Thatcher, MR Redonnet, E Hernady, ... Experimental lung research 32 (5), 181-199, 2006 | 209 | 2006 |
Transglutaminase 2 and its role in pulmonary fibrosis KC Olsen, RE Sapinoro, RM Kottmann, AA Kulkarni, SE Iismaa, ... American journal of respiratory and critical care medicine 184 (6), 699-707, 2011 | 207 | 2011 |