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Monique Bignoux
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引用次数
引用次数
年份
Patented therapeutic approaches targeting LRP/LR for cancer treatment
L Vania, G Morris, TC Otgaar, MJ Bignoux, M Bernert, J Burns, ...
Expert opinion on therapeutic patents 29 (12), 987-1009, 2019
212019
LRP:: FLAG rescues cells from amyloid-β-mediated cytotoxicity through increased TERT levels and telomerase activity
MJ Bignoux, K Cuttler, TC Otgaar, E Ferreira, BT Letsolo, SFT Weiss
Journal of Alzheimer's Disease 69 (3), 729-741, 2019
122019
LRP/LR specific antibody IgG1-iS18 impedes neurodegeneration in Alzheimer's disease mice
E Ferreira, MJ Bignoux, TC Otgaar, N Tagliatti, K Jovanovic, BT Letsolo, ...
Oncotarget 9 (43), 27059, 2018
112018
LRP:: FLAG reduces phosphorylated tau levels in Alzheimer’s disease cell culture models
K Cuttler, MJ Bignoux, TC Otgaar, S Chigumba, E Ferreira, SFT Weiss
Journal of Alzheimer's Disease 76 (2), 753-768, 2020
52020
LRP:: FLAG reduces phosphorylated tau levels in Alzheimer’s Disease
K Cuttler, MJ Bignoux, TC Otgaar, S Chigumba, E Ferreira, SFT Weiss
bioRxiv, 2020.01. 14.905661, 2020
22020
Downregulation of LRP/LR with siRNA inhibits several cancer hallmarks in lung cancer cells
MJ Bignoux, TC Otgaar, M Bernert, SFT Weiss, E Ferreira
FEBS Open bio 13 (2), 323-340, 2023
12023
Compounds for use in the treatment of parkinson's disease
SFT Weiss, E VAN DER MERWE, K Cuttler, M Bignoux, J Burns
US Patent App. 17/298,415, 2022
12022
A method of decreasing concentration of tau (t) protein and/or phosphorylated tau (t) protein
SFT Weiss, K Cuttler, TC Otgaar, E VAN DER MERWE, MJ Bignoux
US Patent App. 17/609,731, 2023
2023
Targeting LRP/LR for the prevention of tumour formation and metastasis in lung cancer models
M Bignoux
Faculty of Science, University of the Witwatersrand, Johannesburg, South Africa, 2022
2022
Analysis on the effect of overexpressing LRP on amyloid beta and TERT expression
MJ Bignoux, TC Otgaar, BT Letsolo, EFSFT Weiss, MJ Bignoux, ...
stress 121 (7), 1046-1053, 2018
2018
In vivo and in vitro analysis on the effect of LRP/LR on alzheimer's disease related proteins, TERT expression and telomerase activity in alzheimer's disease models
M Bignoux
2018
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