关注
Michael W.  Lutz
Michael W. Lutz
Professor of Neurology and Pathology, Duke University
在 duke.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease
AD Roses, MW Lutz, H Amrine-Madsen, AM Saunders, DG Crenshaw, ...
The pharmacogenomics journal 10 (5), 375-384, 2010
4702010
Design, synthesis, and pharmacological evaluation of ultrashort-to long-acting opioid analgesics
PL Feldman, MK James, MF Brackeen, JM Bilotta, SV Schuster, AP Lahey, ...
Journal of medicinal chemistry 34 (7), 2202-2208, 1991
2951991
The cubic ternary complex receptor–occupancy model I. Model description
JM Weiss, PH Morgan, MW Lutz, TP Kenakin
Journal of theoretical biology 178 (2), 151-167, 1996
2551996
The cubic ternary complex receptor-occupancy model III. Resurrecting efficacy
JM Weiss, PH Morgan, MW Lutz, TP Kenakin
Journal of theoretical biology 181 (4), 381-397, 1996
2501996
A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing
G Davies, SE Harris, CA Reynolds, A Payton, HM Knight, DC Liewald, ...
Molecular psychiatry 19 (1), 76-87, 2014
2082014
Novel loci and pathways significantly associated with longevity
YI Zeng, C Nie, J Min, X Liu, M Li, H Chen, H Xu, M Wang, T Ni, Y Li, ...
Scientific reports 6 (1), 21243, 2016
2002016
Two sensitive PCR-based methods for detection of hepatitis B virus variants associated with reduced susceptibility to lamivudine
MI Allen, J Gauthier, M DesLauriers, EJ Bourne, KM Carrick, F Baldanti, ...
Journal of clinical microbiology 37 (10), 3338-3347, 1999
1751999
Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine
J Gauthier, EJ Bourne, MW Lutz, LM Crowther, JL Dienstag, NA Brown, ...
Journal of Infectious Diseases 180 (6), 1757-1762, 1999
1671999
The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ɛ3/ɛ3 genotype
SC Johnson, A La Rue, BP Hermann, G Xu, RL Koscik, EM Jonaitis, ...
Alzheimer's & Dementia 7 (4), 456-465, 2011
1482011
Genetic variation at a single locus and age of onset for Alzheimer's disease
MW Lutz, DG Crenshaw, AM Saunders, AD Roses
Alzheimer's & Dementia 6 (2), 125-131, 2010
1252010
The cubic ternary complex receptor–occupancy model II. Understanding apparent affinity
JM Weiss, PH Morgan, MW Lutz, TP Kenakin
Journal of theoretical biology 178 (2), 169-182, 1996
1251996
The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes
C Linnertz, L Anderson, W Gottschalk, D Crenshaw, MW Lutz, J Allen, ...
Alzheimer's & Dementia 10 (5), 541-551, 2014
962014
The broad impact of TOM40 on neurodegenerative diseases in aging
WK Gottschalk, MW Lutz, YT He, AM Saunders, DK Burns, AD Roses, ...
Journal of Parkinson's disease and Alzheimer's disease 1 (1), 2014
952014
Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936
DM Lyall, SE Harris, ME Bastin, SM Maniega, C Murray, MW Lutz, ...
Neurobiology of aging 35 (6), 1513. e25-1513. e33, 2014
902014
Structure activity relationships of a series of buspirone analogs at alpha-1 adrenoceptors: further evidence that rat aorta alpha-1 adrenoceptors are of the alpha-1D-subtype.
DL Saussy, AS Goetz, KL Queen, HK King, MW Lutz, TJ Rimele
Journal of Pharmacology and Experimental Therapeutics 278 (1), 136-144, 1996
881996
Peak alignment of urine NMR spectra using fuzzy warping
W Wu, M Daszykowski, B Walczak, BC Sweatman, SC Connor, ...
Journal of Chemical Information and Modeling 46 (2), 863-875, 2006
862006
Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3 …
DK Burns, RC Alexander, KA Welsh-Bohmer, M Culp, C Chiang, J O’Neil, ...
The Lancet Neurology 20 (7), 537-547, 2021
842021
Longitudinal modeling of cognitive aging and the TOMM40 effect
RJ Caselli, AC Dueck, MJ Huentelman, MW Lutz, AM Saunders, ...
Alzheimer's & Dementia 8 (6), 490-495, 2012
792012
Characterization of the poly-T variant in the TOMM40 gene in diverse populations
C Linnertz, AM Saunders, MW Lutz, DM Crenshaw, I Grossman, DK Burns, ...
PloS one 7 (2), e30994, 2012
792012
Using genetics to enable studies on the prevention of Alzheimer's disease
DG Crenshaw, WK Gottschalk, MW Lutz, I Grossman, AM Saunders, ...
Clinical Pharmacology & Therapeutics 93 (2), 177-185, 2013
772013
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