A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease AD Roses, MW Lutz, H Amrine-Madsen, AM Saunders, DG Crenshaw, ... The pharmacogenomics journal 10 (5), 375-384, 2010 | 470 | 2010 |
Design, synthesis, and pharmacological evaluation of ultrashort-to long-acting opioid analgesics PL Feldman, MK James, MF Brackeen, JM Bilotta, SV Schuster, AP Lahey, ... Journal of medicinal chemistry 34 (7), 2202-2208, 1991 | 295 | 1991 |
The cubic ternary complex receptor–occupancy model I. Model description JM Weiss, PH Morgan, MW Lutz, TP Kenakin Journal of theoretical biology 178 (2), 151-167, 1996 | 255 | 1996 |
The cubic ternary complex receptor-occupancy model III. Resurrecting efficacy JM Weiss, PH Morgan, MW Lutz, TP Kenakin Journal of theoretical biology 181 (4), 381-397, 1996 | 250 | 1996 |
A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing G Davies, SE Harris, CA Reynolds, A Payton, HM Knight, DC Liewald, ... Molecular psychiatry 19 (1), 76-87, 2014 | 208 | 2014 |
Novel loci and pathways significantly associated with longevity YI Zeng, C Nie, J Min, X Liu, M Li, H Chen, H Xu, M Wang, T Ni, Y Li, ... Scientific reports 6 (1), 21243, 2016 | 200 | 2016 |
Two sensitive PCR-based methods for detection of hepatitis B virus variants associated with reduced susceptibility to lamivudine MI Allen, J Gauthier, M DesLauriers, EJ Bourne, KM Carrick, F Baldanti, ... Journal of clinical microbiology 37 (10), 3338-3347, 1999 | 175 | 1999 |
Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine J Gauthier, EJ Bourne, MW Lutz, LM Crowther, JL Dienstag, NA Brown, ... Journal of Infectious Diseases 180 (6), 1757-1762, 1999 | 167 | 1999 |
The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ɛ3/ɛ3 genotype SC Johnson, A La Rue, BP Hermann, G Xu, RL Koscik, EM Jonaitis, ... Alzheimer's & Dementia 7 (4), 456-465, 2011 | 148 | 2011 |
Genetic variation at a single locus and age of onset for Alzheimer's disease MW Lutz, DG Crenshaw, AM Saunders, AD Roses Alzheimer's & Dementia 6 (2), 125-131, 2010 | 125 | 2010 |
The cubic ternary complex receptor–occupancy model II. Understanding apparent affinity JM Weiss, PH Morgan, MW Lutz, TP Kenakin Journal of theoretical biology 178 (2), 169-182, 1996 | 125 | 1996 |
The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes C Linnertz, L Anderson, W Gottschalk, D Crenshaw, MW Lutz, J Allen, ... Alzheimer's & Dementia 10 (5), 541-551, 2014 | 96 | 2014 |
The broad impact of TOM40 on neurodegenerative diseases in aging WK Gottschalk, MW Lutz, YT He, AM Saunders, DK Burns, AD Roses, ... Journal of Parkinson's disease and Alzheimer's disease 1 (1), 2014 | 95 | 2014 |
Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936 DM Lyall, SE Harris, ME Bastin, SM Maniega, C Murray, MW Lutz, ... Neurobiology of aging 35 (6), 1513. e25-1513. e33, 2014 | 90 | 2014 |
Structure activity relationships of a series of buspirone analogs at alpha-1 adrenoceptors: further evidence that rat aorta alpha-1 adrenoceptors are of the alpha-1D-subtype. DL Saussy, AS Goetz, KL Queen, HK King, MW Lutz, TJ Rimele Journal of Pharmacology and Experimental Therapeutics 278 (1), 136-144, 1996 | 88 | 1996 |
Peak alignment of urine NMR spectra using fuzzy warping W Wu, M Daszykowski, B Walczak, BC Sweatman, SC Connor, ... Journal of Chemical Information and Modeling 46 (2), 863-875, 2006 | 86 | 2006 |
Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3 … DK Burns, RC Alexander, KA Welsh-Bohmer, M Culp, C Chiang, J O’Neil, ... The Lancet Neurology 20 (7), 537-547, 2021 | 84 | 2021 |
Longitudinal modeling of cognitive aging and the TOMM40 effect RJ Caselli, AC Dueck, MJ Huentelman, MW Lutz, AM Saunders, ... Alzheimer's & Dementia 8 (6), 490-495, 2012 | 79 | 2012 |
Characterization of the poly-T variant in the TOMM40 gene in diverse populations C Linnertz, AM Saunders, MW Lutz, DM Crenshaw, I Grossman, DK Burns, ... PloS one 7 (2), e30994, 2012 | 79 | 2012 |
Using genetics to enable studies on the prevention of Alzheimer's disease DG Crenshaw, WK Gottschalk, MW Lutz, I Grossman, AM Saunders, ... Clinical Pharmacology & Therapeutics 93 (2), 177-185, 2013 | 77 | 2013 |