Mechanisms of cell-to-cell transmission of pathological tau: a review GS Gibbons, VMY Lee, JQ Trojanowski JAMA neurology 76 (1), 101-108, 2019 | 207 | 2019 |
Transmission of tauopathy strains is independent of their isoform composition Z He, JD McBride, H Xu, L Changolkar, S Kim, B Zhang, S Narasimhan, ... Nature communications 11 (1), 7, 2020 | 118 | 2020 |
Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau NF Darwich, JM Phan, B Kim, ER Suh, JD Papatriantafyllou, L Changolkar, ... Science 370 (6519), eaay8826, 2020 | 105 | 2020 |
Detection of Alzheimer disease (AD)-specific tau pathology in AD and nonAD tauopathies by immunohistochemistry with novel conformation-selective tau antibodies GS Gibbons, RA Banks, B Kim, L Changolkar, DM Riddle, SN Leight, ... Journal of Neuropathology & Experimental Neurology 77 (3), 216-228, 2018 | 90 | 2018 |
Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer’s disease JD Arena, DH Smith, EB Lee, GS Gibbons, DJ Irwin, JL Robinson, ... Brain 143 (5), 1572-1587, 2020 | 68 | 2020 |
Primary tau pathology, not copathology, correlates with clinical symptoms in PSP and CBD JL Robinson, N Yan, C Caswell, SX Xie, ER Suh, VM Van Deerlin, ... Journal of Neuropathology & Experimental Neurology 79 (3), 296-304, 2020 | 49 | 2020 |
GFP-mutant human tau transgenic mice develop tauopathy following CNS injections of Alzheimer's brain-derived pathological tau or synthetic mutant human tau fibrils GS Gibbons, RA Banks, B Kim, H Xu, L Changolkar, SN Leight, ... Journal of Neuroscience 37 (47), 11485-11494, 2017 | 48 | 2017 |
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics H Xu, M O’Reilly, GS Gibbons, L Changolkar, JD McBride, DM Riddle, ... Acta neuropathologica 141, 193-215, 2021 | 44 | 2021 |
Characterization of tau binding by gosuranemab R Sopko, O Golonzhka, J Arndt, C Quan, J Czerkowicz, A Cameron, ... Neurobiology of Disease 146, 105120, 2020 | 42 | 2020 |
Detection of Alzheimer’s disease (AD) specific tau pathology with conformation-selective anti-tau monoclonal antibody in co-morbid frontotemporal lobar degeneration-tau (FTLD-tau) GS Gibbons, SJ Kim, JL Robinson, L Changolkar, DJ Irwin, LM Shaw, ... Acta neuropathologica communications 7, 1-12, 2019 | 37 | 2019 |
Tau immunotherapy is associated with glial responses in FTLD-tau B Kim, B Mikytuck, E Suh, GS Gibbons, VM Van Deerlin, SN Vaishnavi, ... Acta neuropathologica 142 (2), 243-257, 2021 | 34 | 2021 |
ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degeneration KAQ Cousins, JS Phillips, DJ Irwin, EB Lee, DA Wolk, LM Shaw, ... Alzheimer's & dementia 17 (5), 822-830, 2021 | 30 | 2021 |
Astroglial tau pathology alone preferentially concentrates at sulcal depths in chronic traumatic encephalopathy neuropathologic change JD Arena, VE Johnson, EB Lee, GS Gibbons, DH Smith, JQ Trojanowski, ... Brain Communications 2 (2), fcaa210, 2020 | 29 | 2020 |
Synthesis of cyclic allyl vinyl ethers using Pt (II)-catalyzed isomerization of oxo-alkynes Z Wang, X Lin, RL Luck, G Gibbons, S Fang Tetrahedron 65 (13), 2643-2648, 2009 | 28 | 2009 |
Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease GS Gibbons, SJ Kim, Q Wu, DM Riddle, SN Leight, L Changolkar, H Xu, ... Molecular Neurodegeneration 15, 1-19, 2020 | 27 | 2020 |
ATN status in amnestic and non-amnestic Alzheimer’s disease and frontotemporal lobar degeneration KAQ Cousins, DJ Irwin, DA Wolk, EB Lee, LMJ Shaw, JQ Trojanowski, ... Brain 143 (7), 2295-2311, 2020 | 27 | 2020 |
Synthesis of orthogonally reactive FK506 derivatives via olefin cross metathesis PS Marinec, CG Evans, GS Gibbons, MA Tarnowski, DL Overbeek, ... Bioorganic & medicinal chemistry 17 (16), 5763-5768, 2009 | 25 | 2009 |
One-pot refolding of core histones from bacterial inclusion bodies allows rapid reconstitution of histone octamer YT Lee, G Gibbons, SY Lee, Z Nikolovska-Coleska, Y Dou Protein expression and purification 110, 89-94, 2015 | 23 | 2015 |
Regulation of Wnt signaling target gene expression by the histone methyltransferase DOT1L GS Gibbons, SR Owens, ER Fearon, Z Nikolovska-Coleska ACS chemical biology 10 (1), 109-114, 2015 | 23 | 2015 |
Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum DT Ohm, C Peterson, R Lobrovich, KAQ Cousins, GS Gibbons, ... Acta neuropathologica 140, 675-693, 2020 | 18 | 2020 |