A SIRT2-selective inhibitor promotes c-Myc oncoprotein degradation and exhibits broad anticancer activity H Jing, J Hu, B He, YLN Abril, J Stupinski, K Weiser, M Carbonaro, ... Cancer cell 29 (3), 297-310, 2016 | 280 | 2016 |
Design and synthesis of class-selective activity probes for protein tyrosine phosphatases LC Lo, TL Pang, CH Kuo, YL Chiang, HY Wang, JJ Lin Journal of Proteome Research 1 (1), 35-40, 2002 | 159 | 2002 |
Non-oncogene addiction to SIRT3 plays a critical role in lymphomagenesis M Li, YL Chiang, CA Lyssiotis, MR Teater, JY Hong, H Shen, L Wang, ... Cancer cell 35 (6), 916-931. e9, 2019 | 100 | 2019 |
Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer YLN Abril, IR Fernandez, JY Hong, YL Chiang, DA Kutateladze, Q Zhao, ... Oncogene 40 (9), 1644-1658, 2021 | 55 | 2021 |
Study of the preferred modification sites of the quinone methide intermediate resulting from the latent trapping device of the activity probes for hydrolases LC Lo, YL Chiang, CH Kuo, HK Liao, YJ Chen, JJ Lin Biochemical and biophysical research communications 326 (1), 30-35, 2004 | 38 | 2004 |
An improved fluorogenic assay for SIRT1, SIRT2, and SIRT3 YL Chiang, H Lin Organic & biomolecular chemistry 14 (7), 2186-2190, 2016 | 31 | 2016 |
Enantioselective, Chromatography-Free Synthesis of β3-Amino Acids with Natural and Unnatural Side Chains T Gerfaud, YL Chiang, I Kreituss, JA Russak, JW Bode Organic Process Research & Development 16 (4), 687-696, 2012 | 28 | 2012 |
Discovery of potent small-molecule inhibitors of WDR5-MYC interaction J Ding, G Li, H Liu, L Liu, Y Lin, J Gao, G Zhou, L Shen, M Zhao, Y Yu, ... ACS Chemical Biology 18 (1), 34-40, 2023 | 21 | 2023 |
Synthesis of Enantiomerically Pure Isoxazolidine Monomers for the Preparation of β3‐Oligopeptides by Iterative α‐Keto AcidHydroxylamine (KAHA) Ligations YL Chiang, JA Russak, N Carrillo, JW Bode Helvetica Chimica Acta 95 (12), 2481-2501, 2012 | 17 | 2012 |
Facile synthesis toward the construction of an activity probe library for glycosidases TH Shie, YL Chiang, JJ Lin, YK Li, LC Lo Carbohydrate research 341 (4), 443-456, 2006 | 10 | 2006 |
Discovery and structure-based design of inhibitors of the WD repeat-containing protein 5 (WDR5)–MYC interaction J Ding, L Liu, YL Chiang, M Zhao, H Liu, F Yang, L Shen, Y Lin, H Deng, ... Journal of Medicinal Chemistry 66 (12), 8310-8323, 2023 | 9 | 2023 |
SIRT3 is a novel metabolic driver of and therapeutic target for chemotherapy resistant Dlbcls M Li, YL Chiang, C Lyssiotis, M Teater, H Shen, L Wang, JY Hong, H Jin, ... Blood 130, 643, 2017 | 4 | 2017 |
Sequence-controlled synthesis of beta3-peptides: Solid-phase synthesis and DNA-templated synthesis YL Chiang University of Pennsylvania, 2013 | | 2013 |
Profiling SIRT5 loss-of-function in humans identifies its critical role in redox homeostasis T Yuan, J Keijer, A Bunschoten, Y Hong, Y Chiang, DA Kutateladze, ... Small change, big impact: Functional characterization of human SIRT5 …, 0 | | |