Amphiphilic indole derivatives as antimycobacterial agents: structure–activity relationships and membrane targeting properties T Yang, W Moreira, SA Nyantakyi, H Chen, DB Aziz, ML Go, T Dick Journal of medicinal chemistry 60 (7), 2745-2763, 2017 | 79 | 2017 |
The mycobacterial membrane: a novel target space for anti-tubercular drugs H Chen, SA Nyantakyi, M Li, P Gopal, DB Aziz, T Yang, W Moreira, ... Frontiers in microbiology 9, 1627, 2018 | 52 | 2018 |
Indolyl azaspiroketal Mannich bases are potent antimycobacterial agents with selective membrane permeabilizing effects and in vivo activity SA Nyantakyi, M Li, P Gopal, M Zimmerman, V Dartois, M Gengenbacher, ... Journal of medicinal chemistry 61 (13), 5733-5750, 2018 | 33 | 2018 |
Indolylalkyltriphenylphosphonium analogues are membrane-depolarizing mycobactericidal agents M Li, SA Nyantakyi, P Gopal, DB Aziz, T Dick, ML Go ACS medicinal chemistry letters 8 (11), 1165-1170, 2017 | 31 | 2017 |
Potency increase of spiroketal analogs of membrane inserting indolyl mannich base antimycobacterials is due to acquisition of MmpL3 inhibition M Li, ZY Phua, Y Xi, Z Xu, SA Nyantakyi, W Li, M Jackson, MW Wong, ... ACS infectious diseases 6 (7), 1882-1893, 2020 | 16 | 2020 |
Amide–amine replacement in indole-2-carboxamides yields potent mycobactericidal agents with improved water solubility YJ Tan, M Li, GA Gunawan, SA Nyantakyi, T Dick, ML Go, Y Lam ACS Medicinal Chemistry Letters 12 (5), 704-712, 2020 | 14 | 2020 |
Resistance against membrane-inserting MmpL3 inhibitor through upregulation of MmpL5 in Mycobacterium tuberculosis M Li, SA Nyantakyi, ML Go, T Dick Antimicrobial agents and chemotherapy 64 (12), 10.1128/aac. 01100-20, 2020 | 3 | 2020 |
Resistance against membrane-inserting MmpL3 inhibitor through upregulation of MmpL5 in M. tuberculosis. M Li, SA Nyantakyi, ML Go, T Dick American Society for Microbiology, 2020 | | 2020 |