| Crystal structure of the β2 adrenergic receptor–Gs protein complex SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ... Nature 477 (7366), 549-555, 2011 | 3481 | 2011 |
| Crystal structure of the µ-opioid receptor bound to a morphinan antagonist A Manglik, AC Kruse, TS Kobilka, FS Thian, JM Mathiesen, RK Sunahara, ... Nature 485 (7398), 321-326, 2012 | 1614 | 2012 |
| Activation and allosteric modulation of a muscarinic acetylcholine receptor AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ... Nature 504 (7478), 101-106, 2013 | 975 | 2013 |
| Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist K Haga, AC Kruse, H Asada, T Yurugi-Kobayashi, M Shiroishi, C Zhang, ... Nature 482 (7386), 547-551, 2012 | 931 | 2012 |
| Structure and dynamics of the M3 muscarinic acetylcholine receptor AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ... Nature 482 (7386), 552-556, 2012 | 926 | 2012 |
| Structure of the δ-opioid receptor bound to naltrindole S Granier, A Manglik, AC Kruse, TS Kobilka, FS Thian, WI Weis, ... Nature 485 (7398), 400-404, 2012 | 832 | 2012 |
| Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody AM Ring, A Manglik, AC Kruse, MD Enos, WI Weis, KC Garcia, BK Kobilka Nature 502 (7472), 575-579, 2013 | 543 | 2013 |
| Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, R Chandra, MA Goren, ... Nature methods 7 (12), 1003-1008, 2010 | 527 | 2010 |
| SEDS proteins are a widespread family of bacterial cell wall polymerases AJ Meeske, EP Riley, WP Robins, T Uehara, JJ Mekalanos, D Kahne, ... Nature 537 (7622), 634-638, 2016 | 510 | 2016 |
| Crystal structure of the human σ1 receptor HR Schmidt, S Zheng, E Gurpinar, A Koehl, A Manglik, AC Kruse Nature 532 (7600), 527-530, 2016 | 484 | 2016 |
| Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide AK Shukla, A Manglik, AC Kruse, K Xiao, RI Reis, WC Tseng, DP Staus, ... Nature 497 (7447), 137-141, 2013 | 475 | 2013 |
| Muscarinic acetylcholine receptors: novel opportunities for drug development AC Kruse, BK Kobilka, D Gautam, PM Sexton, A Christopoulos, J Wess Nature reviews Drug discovery 13 (7), 549-560, 2014 | 448 | 2014 |
| Yeast surface display platform for rapid discovery of conformationally selective nanobodies C McMahon, AS Baier, R Pascolutti, M Wegrecki, S Zheng, JX Ong, ... Nature structural & molecular biology 25 (3), 289-296, 2018 | 438 | 2018 |
| Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging RL Maute, SR Gordon, AT Mayer, MN McCracken, A Natarajan, NG Ring, ... Proceedings of the National Academy of Sciences 112 (47), E6506-E6514, 2015 | 389 | 2015 |
| Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ... Nature 535 (7612), 448-452, 2016 | 338 | 2016 |
| T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex JJ Adams, S Narayanan, B Liu, ME Birnbaum, AC Kruse, NA Bowerman, ... Immunity 35 (5), 681-693, 2011 | 299 | 2011 |
| Protein design and variant prediction using autoregressive generative models JE Shin, AJ Riesselman, AW Kollasch, C McMahon, E Simon, C Sander, ... Nature communications 12 (1), 2403, 2021 | 297 | 2021 |
| FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein A Taguchi, MA Welsh, LS Marmont, W Lee, M Sjodt, AC Kruse, D Kahne, ... Nature microbiology 4 (4), 587-594, 2019 | 293 | 2019 |
| Identification of the gene that codes for the σ2 receptor A Alon, HR Schmidt, MD Wood, JJ Sahn, SF Martin, AC Kruse Proceedings of the National Academy of Sciences 114 (27), 7160-7165, 2017 | 293 | 2017 |
| Crystal structure of a full-length human tetraspanin reveals a cholesterol-binding pocket B Zimmerman, B Kelly, BJ McMillan, TCM Seegar, RO Dror, AC Kruse, ... Cell 167 (4), 1041-1051. e11, 2016 | 286 | 2016 |
