关注
Elaine Youngman
Elaine Youngman
Principal Scientist, Interius Biotherapeutics
在 interiusbio.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Functional profiling of the Saccharomyces cerevisiae genome
G Giaever, AM Chu, L Ni, C Connelly, L Riles, S Véronneau, S Dow, ...
nature 418 (6896), 387-391, 2002
52112002
Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline
W Gu, M Shirayama, D Conte, J Vasale, PJ Batista, JM Claycomb, ...
Molecular cell 36 (2), 231-244, 2009
5482009
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth
EJ Duh, HS Yang, I Suzuma, M Miyagi, E Youngman, K Mori, M Katai, ...
Investigative ophthalmology & visual science 43 (3), 821-829, 2002
4852002
C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts
HC Lee, W Gu, M Shirayama, E Youngman, D Conte, CC Mello
Cell 150 (1), 78-87, 2012
4432012
The active site of the ribosome is composed of two layers of conserved nucleotides with distinct roles in peptide bond formation and peptide release
EM Youngman, JL Brunelle, AB Kochaniak, R Green
Cell 117 (5), 589-599, 2004
4122004
CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors
W Gu, HC Lee, D Chaves, EM Youngman, GJ Pazour, D Conte, CC Mello
Cell 151 (7), 1488-1500, 2012
2542012
Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway
JJ Vasale, W Gu, C Thivierge, PJ Batista, JM Claycomb, EM Youngman, ...
Proceedings of the National Academy of Sciences 107 (8), 3582-3587, 2010
2222010
A core nucleosome surface crucial for transcriptional silencing
JH Park, MS Cosgrove, E Youngman, C Wolberger, JD Boeke
Nature genetics 32 (2), 273-279, 2002
1762002
Peptide release on the ribosome: mechanism and implications for translational control
EM Youngman, ME McDonald, R Green
Annu. Rev. Microbiol. 62 (1), 353-373, 2008
1142008
The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity
JL Brunelle, EM Youngman, D Sharma, R Green
Rna 12 (1), 33-39, 2006
1142006
Affinity purification of in vivo-assembled ribosomes for in vitro biochemical analysis
EM Youngman, R Green
Methods 36 (3), 305-312, 2005
1032005
Stop codon recognition by release factors induces structural rearrangement of the ribosomal decoding center that is productive for peptide release
EM Youngman, SL He, LJ Nikstad, R Green
Molecular cell 28 (4), 533-543, 2007
922007
From early lessons to new frontiers: the worm as a treasure trove of small RNA biology
EM Youngman, JM Claycomb
Frontiers in genetics 5, 416, 2014
752014
Peptide release on the ribosome depends critically on the 2′ OH of the peptidyl–tRNA substrate
JL Brunelle, JJ Shaw, EM Youngman, R Green
Rna 14 (8), 1526-1531, 2008
512008
Ribosomal translocation: LepA does it backwards
EM Youngman, R Green
Current Biology 17 (4), R136-R139, 2007
232007
Two distinct conformations of the conserved RNA-rich decoding center of the small ribosomal subunit are recognized by tRNAs and release factors
EM Youngman, L Cochella, JL Brunelle, S He, R Green
Cold Spring Harbor symposia on quantitative biology 71, 545-549, 2006
222006
Development of a highly-sensitive RT-qPCR assay for the detection and quantitation of siRNAs to further understand their role in mRNA quality control in Caenorhabditis elegans
J Castellani, E Youngman
Journal of Biological Chemistry 299 (3), S679, 2023
2023
A genetic screen for proteins involved in Non‐Stop mRNA decay in C. elegans
M Diamandi, C Brennan, EM Youngman
The FASEB Journal 36, 2022
2022
Endogenous siRNAs are required for a learned pathogen avoidance behavior in Caenorhabditis elegans
Y Manzanet, N Salerno, EM Youngman
The FASEB Journal 33 (S1), 778.6-778.6, 2019
2019
A genetic dissection of endogenous siRNA involvement in the nonstop decay pathway in C. elegans
E Mortezavi
Villanova University, 2019
2019
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