Functional profiling of the Saccharomyces cerevisiae genome G Giaever, AM Chu, L Ni, C Connelly, L Riles, S Véronneau, S Dow, ... nature 418 (6896), 387-391, 2002 | 5211 | 2002 |
Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline W Gu, M Shirayama, D Conte, J Vasale, PJ Batista, JM Claycomb, ... Molecular cell 36 (2), 231-244, 2009 | 548 | 2009 |
Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth EJ Duh, HS Yang, I Suzuma, M Miyagi, E Youngman, K Mori, M Katai, ... Investigative ophthalmology & visual science 43 (3), 821-829, 2002 | 485 | 2002 |
C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts HC Lee, W Gu, M Shirayama, E Youngman, D Conte, CC Mello Cell 150 (1), 78-87, 2012 | 443 | 2012 |
The active site of the ribosome is composed of two layers of conserved nucleotides with distinct roles in peptide bond formation and peptide release EM Youngman, JL Brunelle, AB Kochaniak, R Green Cell 117 (5), 589-599, 2004 | 412 | 2004 |
CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors W Gu, HC Lee, D Chaves, EM Youngman, GJ Pazour, D Conte, CC Mello Cell 151 (7), 1488-1500, 2012 | 254 | 2012 |
Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway JJ Vasale, W Gu, C Thivierge, PJ Batista, JM Claycomb, EM Youngman, ... Proceedings of the National Academy of Sciences 107 (8), 3582-3587, 2010 | 222 | 2010 |
A core nucleosome surface crucial for transcriptional silencing JH Park, MS Cosgrove, E Youngman, C Wolberger, JD Boeke Nature genetics 32 (2), 273-279, 2002 | 176 | 2002 |
Peptide release on the ribosome: mechanism and implications for translational control EM Youngman, ME McDonald, R Green Annu. Rev. Microbiol. 62 (1), 353-373, 2008 | 114 | 2008 |
The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity JL Brunelle, EM Youngman, D Sharma, R Green Rna 12 (1), 33-39, 2006 | 114 | 2006 |
Affinity purification of in vivo-assembled ribosomes for in vitro biochemical analysis EM Youngman, R Green Methods 36 (3), 305-312, 2005 | 103 | 2005 |
Stop codon recognition by release factors induces structural rearrangement of the ribosomal decoding center that is productive for peptide release EM Youngman, SL He, LJ Nikstad, R Green Molecular cell 28 (4), 533-543, 2007 | 92 | 2007 |
From early lessons to new frontiers: the worm as a treasure trove of small RNA biology EM Youngman, JM Claycomb Frontiers in genetics 5, 416, 2014 | 75 | 2014 |
Peptide release on the ribosome depends critically on the 2′ OH of the peptidyl–tRNA substrate JL Brunelle, JJ Shaw, EM Youngman, R Green Rna 14 (8), 1526-1531, 2008 | 51 | 2008 |
Ribosomal translocation: LepA does it backwards EM Youngman, R Green Current Biology 17 (4), R136-R139, 2007 | 23 | 2007 |
Two distinct conformations of the conserved RNA-rich decoding center of the small ribosomal subunit are recognized by tRNAs and release factors EM Youngman, L Cochella, JL Brunelle, S He, R Green Cold Spring Harbor symposia on quantitative biology 71, 545-549, 2006 | 22 | 2006 |
Development of a highly-sensitive RT-qPCR assay for the detection and quantitation of siRNAs to further understand their role in mRNA quality control in Caenorhabditis elegans J Castellani, E Youngman Journal of Biological Chemistry 299 (3), S679, 2023 | | 2023 |
A genetic screen for proteins involved in Non‐Stop mRNA decay in C. elegans M Diamandi, C Brennan, EM Youngman The FASEB Journal 36, 2022 | | 2022 |
Endogenous siRNAs are required for a learned pathogen avoidance behavior in Caenorhabditis elegans Y Manzanet, N Salerno, EM Youngman The FASEB Journal 33 (S1), 778.6-778.6, 2019 | | 2019 |
A genetic dissection of endogenous siRNA involvement in the nonstop decay pathway in C. elegans E Mortezavi Villanova University, 2019 | | 2019 |