Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability IJ Hidalgo, TJ Raub, RT Borchardt Gastroenterology 96 (2), 736-749, 1989 | 2903 | 1989 |
In vitro models for the blood–brain barrier P Garberg, M Ball, N Borg, R Cecchelli, L Fenart, RD Hurst, T Lindmark, ... Toxicology in vitro 19 (3), 299-334, 2005 | 494 | 2005 |
Quantitative approaches to delineate paracellular diffusion in cultured epithelial cell monolayers A Adson, TJ Raub, PS Burton, CL Barsuhn, AR Hilgers, KL Audus, ... Journal of pharmaceutical sciences 83 (11), 1529-1536, 1994 | 335 | 1994 |
P-glycoprotein recognition of substrates and circumvention through rational drug design TJ Raub Molecular pharmaceutics 3 (1), 3-25, 2006 | 279 | 2006 |
Brain exposure of two selective dual CDK4 and CDK6 inhibitors and the antitumor activity of CDK4 and CDK6 inhibition in combination with temozolomide in an intracranial … TJ Raub, GN Wishart, P Kulanthaivel, BA Staton, RT Ajamie, GA Sawada, ... Drug Metabolism and Disposition 43 (9), 1360-1371, 2015 | 259 | 2015 |
Discovery of N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential … DG Wishka, DP Walker, KM Yates, SC Reitz, S Jia, JK Myers, KL Olson, ... Journal of medicinal chemistry 49 (14), 4425-4436, 2006 | 236 | 2006 |
Passive diffusion of weak organic electrolytes across Caco‐2 cell monolayers: Uncoupling the contributions of hydrodynamic, transcellular, and paracellular barriers A Adson, PS Burton, TJ Raub, CL Barsuhn, KL Audus, NFH Ho Journal of pharmaceutical sciences 84 (10), 1197-1204, 1995 | 213 | 1995 |
Permeability of bovine brain microvessel endothelial cells in vitro: barrier tightening by a factor released from astroglioma cells TJ Raub, SL Kuentzel, GA Sawada Experimental cell research 199 (2), 330-340, 1992 | 204 | 1992 |
Determination of the affinity of drugs toward serum albumin by measurement of the quenching of the intrinsic tryptophan fluorescence of the protein DE Epps, TJ Raub, V Caiolfa, A Chiari, M Zamai Journal of Pharmacy and Pharmacology 51 (1), 41-48, 1999 | 201 | 1999 |
The Alzheimer β-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells SL Kuentzel, SM Ali, RA Altman, BD Greenberg, TJ Raub Biochemical Journal 295 (2), 367-378, 1993 | 183 | 1993 |
A general, wide-range spectrofluorometric method for measuring the site-specific affinities of drugs toward human serum albumin DE Epps, TJ Raub, FJ Kezdy Analytical biochemistry 227 (2), 342-350, 1995 | 159 | 1995 |
How hydrogen bonds impact P-glycoprotein transport and permeability PV Desai, TJ Raub, MJ Blanco Bioorganic & medicinal chemistry letters 22 (21), 6540-6548, 2012 | 134 | 2012 |
The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice MJ Zamek-Gliszczynski, K Nezasa, X Tian, JC Kalvass, NJ Patel, TJ Raub, ... Molecular pharmacology 70 (6), 2127-2133, 2006 | 121 | 2006 |
Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists DP Walker, DG Wishka, DW Piotrowski, S Jia, SC Reitz, KM Yates, ... Bioorganic & medicinal chemistry 14 (24), 8219-8248, 2006 | 119 | 2006 |
Role of uteroferrin in transplacental iron transport in the pig. RM Roberts, TJ Raub, FW Bazer Federation proceedings 45 (10), 2513-2518, 1986 | 113 | 1986 |
Fluid-phase endocytosis by primary cultures of bovine brain microvessel endothelial cell monolayers FL Guillot, KL Audus, TJ Raub Microvascular research 39 (1), 1-14, 1990 | 108 | 1990 |
Neuroprotective efficacy of microvascularly-localized versus brain-penetrating antioxidants ED Hall, PK Andrus, SL Smith, JA Oostveen, HM Scherch, BS Lutzke, ... Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma, 107-113, 1996 | 107 | 1996 |
Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions TJ Raub American Journal of Physiology-Cell Physiology 271 (2), C495-C503, 1996 | 105 | 1996 |
Discovery of N-[(3R, 5R)-1-azabicyclo [3.2. 1] oct-3-yl] furo [2, 3-c] pyridine-5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo … BA Acker, EJ Jacobsen, BN Rogers, DG Wishka, SC Reitz, DW Piotrowski, ... Bioorganic & Medicinal Chemistry Letters 18 (12), 3611-3615, 2008 | 96 | 2008 |
Recycling kinetics and transcytosis of transferrin in primary cultures of bovine brain microvessel endothelial cells TJ Raub, CR Newton Journal of cellular physiology 149 (1), 141-151, 1991 | 92 | 1991 |