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Vasily Gelfanov
Vasily Gelfanov
在 indiana.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
JW Day, N Ottaway, JT Patterson, V Gelfanov, D Smiley, J Gidda, ...
Nature chemical biology 5 (10), 749-757, 2009
6902009
Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans
B Finan, T Ma, N Ottaway, TD Müller, KM Habegger, KM Heppner, ...
Science translational medicine 5 (209), 209ra151-209ra151, 2013
6202013
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
B Finan, B Yang, N Ottaway, DL Smiley, T Ma, C Clemmensen, ...
Nature medicine 21 (1), 27-36, 2015
6182015
Paclitaxel sensitivity of breast cancer cells with constitutively active NF-κB is enhanced by IκBα super-repressor and parthenolide
NM Patel, S Nozaki, NH Shortle, P Bhat-Nakshatri, TR Newton, S Rice, ...
Oncogene 19 (36), 4159-4169, 2000
3752000
Targeted estrogen delivery reverses the metabolic syndrome
B Finan, B Yang, N Ottaway, K Stemmer, TD Müller, CX Yi, K Habegger, ...
Nature medicine 18 (12), 1847-1856, 2012
2932012
Fibroblast growth factor 21 mediates specific glucagon actions
KM Habegger, K Stemmer, C Cheng, TD Müller, KM Heppner, N Ottaway, ...
Diabetes 62 (5), 1453-1463, 2013
2502013
Unimolecular polypharmacy for treatment of diabetes and obesity
MH Tschöp, B Finan, C Clemmensen, V Gelfanov, D Perez-Tilve, ...
Cell metabolism 24 (1), 51-62, 2016
2302016
Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic impact for metabolic disease
B Finan, C Clemmensen, Z Zhu, K Stemmer, K Gauthier, L Müller, ...
Cell 167 (3), 843-857. e14, 2016
1842016
Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism
PA Mroz, B Finan, V Gelfanov, B Yang, MH Tschöp, RD DiMarchi, ...
Molecular Metabolism 20, 51-62, 2019
1572019
Optimization of co‐agonism at GLP‐1 and glucagon receptors to safely maximize weight reduction in DIO‐rodents
JW Day, V Gelfanov, D Smiley, PE Carrington, G Eiermann, G Chicchi, ...
Peptide Science 98 (5), 443-450, 2012
1442012
Peptide lipidation stabilizes structure to enhance biological function
BP Ward, NL Ottaway, D Perez-Tilve, D Ma, VM Gelfanov, MH Tschöp, ...
Molecular metabolism 2 (4), 468-479, 2013
1192013
Glucagon regulation of energy metabolism
KM Heppner, KM Habegger, J Day, PT Pfluger, D Perez-Tilve, B Ward, ...
Physiology & behavior 100 (5), 545-548, 2010
932010
Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation
LD Cripe, VM Gelfanov, EA Smith, DR Spigel, CA Phillips, TG Gabig, ...
Leukemia 16 (5), 799-812, 2002
832002
Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions
E Altindis, W Cai, M Sakaguchi, F Zhang, W GuoXiao, F Liu, P De Meyts, ...
Proceedings of the National Academy of Sciences 115 (10), 2461-2466, 2018
792018
Optimization of the native glucagon sequence for medicinal purposes
JR Chabenne, MA DiMarchi, VM Gelfanov, RD DiMarchi
Journal of diabetes science and technology 4 (6), 1322-1331, 2010
712010
A glucagon analog chemically stabilized for immediate treatment of life-threatening hypoglycemia
J Chabenne, MDM Chabenne, Y Zhao, J Levy, D Smiley, V Gelfanov, ...
Molecular Metabolism 3 (3), 293-300, 2014
612014
A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1
JT Patterson, N Ottaway, VM Gelfanov, DL Smiley, D Perez-Tilve, ...
ACS Chemical Biology 6 (2), 135-145, 2011
582011
Transformation of interleukin-3–dependent cells without participation of Stat5/bcl-xL: cooperation of akt with raf/erk leads to p65 nuclear factor κB–mediated antiapoptosis …
VM Gelfanov, GS Burgess, S Litz-Jackson, AJ King, MS Marshall, ...
Blood, The Journal of the American Society of Hematology 98 (8), 2508-2517, 2001
552001
Chemical synthesis of insulin analogs through a novel precursor
AN Zaykov, JP Mayer, VM Gelfanov, RD DiMarchi
ACS Chemical Biology 9 (3), 683-691, 2014
472014
Synthesis of four-disulfide insulin analogs via sequential disulfide bond formation
F Wu, JP Mayer, VM Gelfanov, F Liu, RD DiMarchi
The Journal of Organic Chemistry 82 (7), 3506-3512, 2017
332017
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