A highly reactive imidazolium-bridged dinucleotide intermediate in nonenzymatic RNA primer extension T Walton, JW Szostak Journal of the American Chemical Society 138 (36), 11996-12002, 2016 | 97 | 2016 |
The mechanism of nonenzymatic template copying with imidazole‐activated nucleotides T Walton, W Zhang, L Li, CP Tam, JW Szostak Angewandte Chemie International Edition 58 (32), 10812-10819, 2019 | 77 | 2019 |
Structure of a microtubule-bound axonemal dynein T Walton, H Wu, A Brown Nature communications 12 (1), 477, 2021 | 74 | 2021 |
A quantitative model of normal Caenorhabditis elegans embryogenesis and its disruption after stress JL Richards, AL Zacharias, T Walton, JT Burdick, JI Murray Developmental biology 374 (1), 12-23, 2013 | 70 | 2013 |
Axonemal structures reveal mechanoregulatory and disease mechanisms T Walton, M Gui, S Velkova, MR Fassad, RA Hirst, E Haarman, ... Nature 618 (7965), 625-633, 2023 | 62 | 2023 |
A kinetic model of nonenzymatic RNA polymerization by cytidine-5′-phosphoro-2-aminoimidazolide T Walton, JW Szostak Biochemistry 56 (43), 5739-5747, 2017 | 51 | 2017 |
Quantitative Differences in Nuclear β-catenin and TCF Pattern Embryonic Cells in C. elegans AL Zacharias, T Walton, E Preston, JI Murray PLoS genetics 11 (10), e1005585, 2015 | 44 | 2015 |
Gene transcription is coordinated with, but not dependent on, cell divisions during C. elegans embryonic fate specification G Nair, T Walton, JI Murray, A Raj Development 140 (16), 3385-3394, 2013 | 41 | 2013 |
The Bicoid Class Homeodomain Factors ceh-36/OTX and unc-30/PITX Cooperate in C. elegans Embryonic Progenitor Cells to Regulate Robust Development T Walton, E Preston, G Nair, AL Zacharias, A Raj, JI Murray PLoS genetics 11 (3), e1005003, 2015 | 38 | 2015 |
Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex W Zhang, CP Tam, T Walton, AC Fahrenbach, G Birrane, JW Szostak Proceedings of the National Academy of Sciences 114 (29), 7659-7664, 2017 | 37 | 2017 |
Crystallographic observation of nonenzymatic RNA primer extension W Zhang, T Walton, L Li, JW Szostak Elife 7, e36422, 2018 | 35 | 2018 |
In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole–activated substrates T Walton, S DasGupta, D Duzdevich, SS Oh, JW Szostak Proceedings of the National Academy of Sciences 117 (11), 5741-5748, 2020 | 27 | 2020 |
Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension D Duzdevich, CE Carr, D Ding, SJ Zhang, TS Walton, JW Szostak Nucleic Acids Research 49 (7), 3681-3691, 2021 | 24 | 2021 |
Template-directed catalysis of a multistep reaction pathway for nonenzymatic RNA primer extension T Walton, L Pazienza, JW Szostak Biochemistry 58 (6), 755-762, 2018 | 24 | 2018 |
Synthesis of a nonhydrolyzable nucleotide phosphoroimidazolide analogue that catalyzes nonenzymatic RNA primer extension CP Tam, L Zhou, AC Fahrenbach, W Zhang, T Walton, JW Szostak Journal of the American Chemical Society 140 (2), 783-792, 2018 | 13 | 2018 |
Overlapping cell population expression profiling and regulatory inference in C. elegans J Burdick, T Walton, E Preston, A Zacharias, A Raj, JI Murray BMC genomics 17, 1-19, 2016 | 9 | 2016 |
Structural determination and modeling of ciliary microtubules T Walton, MH Doran, A Brown Acta Crystallographica Section D: Structural Biology 80 (4), 2024 | | 2024 |
Transmitotic persistence of Wnt pathway activity diversifies gene expression in C. elegans embryos. A Zacharias, T Walton, E Preston, J Murray MOLECULAR BIOLOGY OF THE CELL 25, 2014 | | 2014 |
Visualization of embryonic development with a downloadable 4D quantitative model AL Zacharias, T Walton, JT Burdick, JI Murray CTGC–a portal for distributing transgenic worms, 0 | | |